Vascular and Endovascular Research Network

With ESVS Society 2024 conference coming to a close, this is a reminder & link/QR code for the major vascular RCTs currently in 🇬🇧/Europe. Please help produce proper high quality evidence, beyond the cohort studies Join as a site & recruit where/when you can. Details in the link, including trials' summaries:qr.codes/AjY1g2 NIHR (National Institute for Health and Care Research) & British Heart Foundation

🚨 Major Milestone for VERN! 🚨 We’re thrilled to announce the publication of the COVER Tier 2 Study, marking the third VERN paper accepted/published this month! 🌍📚 Huge thanks to the incredible efforts of Sandip Nandhra, Panagiota Birmpili, and Ruth A Benson for their contributions to this impactful research as well as all of our collaborators. This study, supported by Circulation Foundation, delivers vital insights into perioperative outcomes for vascular patients during the COVID-19 pandemic, driving improvements in care and outcomes. Explore the full research here: https://lnkd.in/evMg3yx2 Building on the success of VERN’s recent publications, now is the ideal time to get involved in VERN’s ongoing projects—both BLAST and ARMIES are actively recruiting vascular centres. BLAST (Blood Loss, Anaemia and Haemostasis management in Vascular Surgery) has surpassed a significant milestone, with over 300 patients enrolled in the database. The ARMIES (Arm iscahemia) survey has already been accepted for presentation at the prestigious Vascular Society ASM in Brighton. Join us in advancing vascular research and contributing to these groundbreaking studies. #VascularResearch #VERN #BLASTStudy #ARMIES #VascularSurgery #HealthcareInnovation #MedicalResearch #VascularSociety

Hot off the press, the Collaborative Acute Aortic Syndrome Project in now available, Open access, in BJS Open Coordinated by VERN and the UK National Interventional Radiology Trainee Research collaborative, this multicentre study evaluated Acute Aortic Syndrome (AAS) care pathways across 15 UK sites, analysing the critical timelines from symptom onset to treatment in 620 patients. 🩺 What you need to know: This study aimed to evaluate current pathways and understand chronology of AAS patient care, tracking mortality rates at 30 days and 6 months. ⏱ Key Timelines: Time to hospital presentation: 3.1 hrs (faster with sudden chest pain, delayed with migratory pain & hypertension). Time to imaging diagnosis: 3.2 hrs (faster with limb ischaemia, slower with family history of aortic disease). Time to treatment: 2 hrs (significantly delayed by interhospital transfers). 🔑 Key Findings: Delays in diagnosis are common in patients with migratory pain or hypertension. Hospital transfers and non-emergency presentations lead to treatment delays. Mortality predictors: Age over 70, complicated AAS, and lack of critical care admission increase mortality risk. Healthcare disparities: Patients from lower socioeconomic backgrounds, though closer to hospitals, didn’t present sooner—highlighting healthcare inequalities. 🏥 Conclusion: This data provides a crucial understanding of where delays occur in the AAS care pathway and can be used to prioritise research strategies to streamline patient care A remarkable collaboration between Vascular Surgery and Interventional Radiology, working together to improve outcomes for Acute Aortic Syndrome patients and pave the way for future groundbreaking research projects. Aminder Singh, Sandip Nandhra, Jim Zhong, Nawaz Safdar, Ganesh Vigneswaran

🚨 New Study Launch: ARMIES 🚨 Building on the publication success of CAASP and DEFINTIVE in high impact journals, VERN is excited to announce the launch of ARMIES – the Arm Ischaemia Study. Acute upper limb ischaemia is a critical vascular emergency that requires timely intervention. While surgical or endovascular treatment is standard for severe cases, patients with less critical presentations may benefit from medical management. Yet, no randomized controlled trials have directly compared these treatment options. ARMIES will bridge this evidence gap by evaluating current treatment strategies and clinical outcomes against ESVS guidelines. The study will provide crucial insights into AULI incidence, treatment approaches, patient outcomes, and risk factors, helping to shape the future of care for this serious condition. 🔗 Registration is now open – Data collection begins October 7th. 📚 Collaborative authorship and the opportunity to get involved in high quality research with the potential to be published in a high-impact journal await! Don’t miss your chance to contribute to groundbreaking research, sign up here - https://lnkd.in/eBeCnDgM #VascularSurgery #Research #AULI #HealthcareInnovation #HighImpactResearch #VERN #ARMIESStudy

🚀 Another Publication 🚀 Our latest research, "The Definite Study," has been approved for publication in British Journal of Surgery . This international, multicenter study highlights the discrepancies between guidelines and actual practices in treating diabetes-related foot disease. Despite global recommendations from the International Working Group on the Diabetic Foot and the Global Vascular Guidelines, our findings indicate a widespread lack of adherence, affecting clinical outcomes. Thank you to all those who contributed. Stay tuned for more information, including a link to the published paper. If you're interested in participating in VERN projects and exploring collaborative authorship opportunities, the BLAST study is currently open for recruitment. For further details, reach out to the team at Blast.VERN@gmail.com or fill out the registration form provided below.

🌍 Join the BLAST Study: A Global Initiative in Vascular Surgery 🌍 The BLAST study is still open for recruitment. This study is designed to illuminate the current management of perioperative bleeding in major open vascular surgery—a critical area where significant blood loss is common, and 60% of patients require peri-operative transfusions. Despite this, there remains no clear consensus on the use of local and systemic haemostatic agents. Join the growing global community of vascular centres from countries like Italy, Greece, and Australia that have already registered. With over 200 patients entered into the database, there’s still time for your centre to contribute to this important research and benefit from collaborative authorship opportunities. Participants will also gain access to valuable data for local presentations. 🔗 Learn more about the study, view the full protocol and to register please visit our website https://lnkd.in/guhBHyCJ For more information or any questions, feel free to reach out to our research team at blast.VERN@gmail.com. Don’t miss your chance to be part of this vital initiative! #BLASTStudy #VascularSurgery #MedicalResearch #Collaboration

Dragon's Den is back! Do you have an innovative vascular research project that you are passionate about bringing to life? Would you like the chance to receive VERN support and funding to make it happen? We are thrilled to announce the return of Dragon's Den at this year's Vascular Society Annual Scientific Meeting! This is your opportunity to present your groundbreaking research proposal at a national conference.  Since its inception, Dragon's Den has awarded over £20,000, kickstarting more than five published studies and propelling vascular research across the UK. How to Participate: Submit a 300-word project proposal to vern.arterial.disease@gmail.com. Your proposal should include the following: Background: Provide context and the significance of your research. Aims: Clearly outline the goals and objectives of your project. Methods: Describe the methodology and approach you will take. How VERN Will Contribute: Explain how VERN's support will help achieve your research goals.

We are excited to announce that our paper on aortic dissection has been accepted for publication in BJS Open.  This accomplishment is the result of an excellent effort from all collaborators, yielding important findings for patients with aortic dissection. The study was coordinated by two trainee-led research collaboratives, VERN and UNITE, fostering close links between trainees in vascular surgery and interventional radiology. We are also grateful for the support from the The Aortic Dissection Charitable Trust which has been instrumental in our success. We will release further details and including a link to the paper once it has been published.

📢Site Recruitment Extension📢 We have extended the recruitment period for BLAST until the 31st of December. Thank you to all the centres that have already signed up, we now have over 100 patients entered onto the database and it is not too late to get involved. BLAST is an international study focused on examining the management of perioperative bleeding in major open vascular surgery. Vascular surgery has a comorbid population and often involves significant blood loss. While 60% of patients require perioperative transfusion, there is no consensus on the utilisation of local and systemic hemostatic agents. Registration is now open, so seize the opportunity for collaborative authorship! Please feel free to contact us at blast.VERN@gmail.com with any questions or for more information including the study protocol please visit our website at https://lnkd.in/edrN53c6

VERN is thrilled to announce the launch of our LinkedIn and the initial phase of our upcoming research initiative, ARMIES. This project aims to explore treatment approaches and clinical results for individuals with acute upper limb ischaemia. Acute upper limb ischaemia (AULI) is a severe vascular condition. Immediate revascularisation is vital for cases involving paralysis or paraesthesia, while patients experiencing only pain and pallor may receive medical treatment or surgical intervention based on their specific situation. Currently, there is a lack of evidence to direct the management of AULI, particularly in Rutherford IIa cases, regarding the utilization of medical therapy alone or in combination with surgical intervention. The first phase includes a survey to gather data that will shape a future trial. Survey participants will have exclusive early access to the ARMIES project and information on how to participate, including collaborative authorship opportunities. If you would like to get involved we would be grateful if you could complete the following short survey- https://lnkd.in/ekY6Ma6c