The cast of “One Tree Hill” will reunite for an upcoming charity basketball game to benefit the V Foundation for cancer research. Fans can watch the game via a live stream on “House of Highlights,” a leading TNT sports brand.

On May 18, Friends With Benefit Charity Events will reunite the cast “One Tree Hill” basketball team for a game at Laney High School in Wilmington, North Carolina — the gym the Tree Hill Ravens played at in the show and the court where Michael Jordan played high school basketball.

Cast members confirmed to participate include James Lafferty, Robbie Jones, Bryan Greenberg, Paul Johansson, Craig Sheffer, Tyler Hilton, Cullen Moss, Brett Claywell, Stephen Colletti, Lee Norris, Antwon Tanner and Texas Battle. Chad Michael Murray will be making a virtual appearance.

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The game, which is sold out, will be globally live-streamed via House of Highlights YouTube channel at 11 a.m. ET.

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V Foundation for Cancer Research was founded in 1993 by ESPN and North Carolina State University basketball coach, Jim Valvano. It holds an important place in the hearts of many “One Tree Hill” cast members, including Sheffer and Johansson.

“Team Keith versus Team Dan! I’m so excited to lead a team against my friend PJ to raise money and awareness for the V Foundation for cancer research,” Sheffer, who portrayed Keith Scott in the series, said in a statement. “I am a cancer survivor, and have experienced the radiation and crippling anxiety that comes with a cancer diagnosis, so I am happy to be a part of this amazing livestream event to combat the brutal beast that is cancer.”

Johannson added, “Craig and I will be battling for the honor of Tree Hill Basketball superiority! All of us are proud and excited to come together on behalf of the V Foundation. I’ve personally been inspired by the legendary Jimmy V and his courage as a man and his coaching success story and hope to lead our team to victory in the game like the V Foundation is leading the path towards victory over cancer.”

Fans still have the opportunity to attend this sold-out event by entering a charity auction here.

Other cast members from the show will be in Wilmington, NC, for the Friends With Benefit Charity Events weekend. On May 17, Lafferty and Colletti will host a screening of their show, “Everyone Is Doing Great” at TRIC. Later that night, Hilton, Jana Kramer, Kate Voegele and Michael Grubbs will be performing a concert.

After the game, FWB is hosting “Tree Hill High Prom,” with many cast members available for photo ops. Attending talent include James Lafferty, Bryan Greenberg, Tyler Hilton, Robbie Jones, Lee Norris, Antwon Tanner, Brett Claywell, Cullen Moss, Bethany Joy Lenz, Lindsey McKeon, Shantel VanSanten, Danneel Ackles, Joe Manganiello, Vaughan Wilson, Colin Fickes, Amber Wallace, Texas Battle, Drew Seeley, Grace Holcomb, Jaden Harmon and more.

Lastly, on Sunday, May 18, cast members will be available for autographs and photo ops. Many of the above talent will be attending, as well as Sophia Bush, Austin Nichols, Barbara Alyn Woods, Ashley Rickards, Bevin Prince and Kieren Hutchison. Tickets to all events are available at OTHMerch.com.

“One Tree Hill” aired on The WB/The CW from 2003 to 2012, with 187 episodes.

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