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Stay in Santa Cruz Region's best hotels!

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Superb: 9+ Very good: 8+ Good: 7+ Pleasant: 6+
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Cosmopolitano Hotel Boutique 5 stars

Hotel in Santa Cruz de la Sierra

Offering an outdoor pool, Cosmopolitano Hotel Boutique is located in the historical centre of Santa Cruz de la Sierra. Guests can enjoy the on-site bar. Amazing hospitality from the staff here, especially Valeria who we interacted with most during our stay. She has been very helpful and friendly :)! We really liked what they did here with the rooms and common areas, very thoughtful design and we felt like we were in an oasis! We had stayed here for 2 nights and wouldn't mind it to be longer 👍🏻

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9.1
Superb
1,067 reviews
Price from
HK$ 617
per night

Chairu Eco Hotel 4 stars

Hotel in Santa Cruz de la Sierra

Chairu Eco Hotel features a shared lounge, terrace, a restaurant and bar in Santa Cruz de la Sierra. This 4-star hotel offers a concierge service and a tour desk. really modern and clean. the shower was incredible too. the staff are friendly and nice too.

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9
Superb
820 reviews
Price from
HK$ 467
per night

TRYP by Wyndham Santa Cruz 4 stars

Hotel in Santa Cruz de la Sierra

Situated in Santa Cruz de la Sierra, 1.6 km from Gabriel Rene Moreno Autonomous University, TRYP by Wyndham Santa Cruz features accommodation with an outdoor swimming pool, free private parking, a... Great location. Friendly staff.

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9
Superb
514 reviews
Price from
HK$ 623
per night

YVY CASA HOTEL

Hotel in Samaipata

Located in Samaipata, 10 km from Samaipata Fort, YVY CASA HOTEL provides accommodation with a garden, free private parking and a terrace. Really loved the place. It's very cozy, quite and peaceful. I felt like i've visited my aunt, the ambience is very warm and homely. Perfect example of slow living. Thank you

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9.2
Superb
362 reviews
Price from
HK$ 292
per night

Marriott Santa Cruz de la Sierra Hotel 5 stars

Hotel in Santa Cruz de la Sierra

Marriott Santa Cruz de la Sierra Hotel has an outdoor swimming pool, fitness centre, a shared lounge and terrace in Santa Cruz de la Sierra. How we were welcomed by the receptionist Marcela. How Fabricio the bar tender was attentive and eager to please. How Rodrigo was great in the morning during breakfast. Just perfect. Thank you so much for this amazing experience. And again thank you to these three people mentioned above. They deserved to be rewarded.

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9.1
Superb
347 reviews
Price from
HK$ 811
per night

La Vida es Bella

Hotel in Samaipata

Set in Samaipata, 9 km from Samaipata Fort, La Vida es Bella offers accommodation with a garden, free private parking, a shared lounge and a terrace. Great location. Wonderful service. The best breakfast ever. A perfect place to rest and enjoy Samaipata.

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9.3
Superb
111 reviews
Price from
HK$ 467
per night

El Pueblito Hotel Boutique 4 stars

Hotel in Samaipata

Situated in Samaipata, 11 km from Samaipata Fort, El Pueblito Hotel Boutique features accommodation with an outdoor swimming pool, free private parking, a garden and a shared lounge. El Pueblito is a representation of a small town, each room representing parts if the town with exquisite decoration. You have a carpentry, bank, florist, artist’ house, chapel, etc… the view is magnificent. El Pueblito is a nice quiet place to relax. The food is very good as well. The family that owns and runs the hotel is very attentive and warm. 100% recommended!

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9.5
Exceptional
220 reviews
Price from
HK$ 723
per night

Alfonsina Hotel Boutique 5 stars

Hotel in Santa Cruz de la Sierra

Conveniently located only a 10-minute walk from Ventura Shopping Centre, Alfonsina Hotel Boutique. offers accommodations in Santa Cruz de la Sierra. It was an interesting structure well worth visiting just for that - Very modern in design

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9.4
Superb
402 reviews
Price from
HK$ 735
per night

Hotel Cortez 5 stars

Hotel in Santa Cruz de la Sierra

Boasting an outdoor swimming pool, gym and spa facilities, Hotel Cortez has chic and spacious rooms in Santa Cruz de la Sierra. Free WiFi access is available. The staff is very friendly and helpful. Everything is very clean. Excellent breakfast. Nice jacuzzi and great professional massages. Easy to get Uber rides.

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9
Superb
181 reviews
Price from
HK$ 910
per night

Hotel By Armonía Santa Cruz 3 stars

Hotel in Santa Cruz de la Sierra

Set in Santa Cruz de la Sierra, 1.6 km from Güembé Biocentre and Guazú Ivaga Park, Hotel By Armonía Santa Cruz offers accommodation with an outdoor swimming pool, free private parking, a garden and a... Very friendly and caring staff, absolutely everyone were very nice and friendly with us. We enjoyed the breakfast - we got it served, very fast, - it was very ample and nutritious; the swimming pool was warm, clean and deep enough; the interior as well as the exterior were fantastic, we enjoyed the garden and the location too - it was very quiet. Good wifi, excellent spacious shower room.

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9.1
Superb
58 reviews
Price from
HK$ 595
per night

Hotels with extra health and safety measures

Find hotels in Santa Cruz Region with added hygiene measures plus high cleanliness ratings

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