CHEBI:9506 - tetrodotoxin

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ChEBI Name tetrodotoxin
ChEBI ID CHEBI:9506
Definition A quinazoline alkaloid that is a marine toxin isolated from fish such as puffer fish. It has been shown to exhibit potential neutotoxicity due to its ability to block voltage-gated sodium channels.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Biological Role(s): marine metabolite
Any metabolite produced during a metabolic reaction in marine macro- and microorganisms.
animal metabolite
Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals.
bacterial metabolite
Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
voltage-gated sodium channel blocker
Any sodium channel blocker that interferes with the activity of voltage-gated sodium channels.
neurotoxin
A poison that interferes with the functions of the nervous system.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
Related Structures
tetrodotoxin is a Functional Parent of
(11S,13S)-3-Amino-5,12,13,14-tetrahydroxy-14-(hydroxymethyl)-8,10-dioxa-2-aza-4-azoniatetracyclo[7.3.1.17,11.01,6]tetradec-3-en-9-olate
Mass : 319.270
182163
(11s,13s)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1~7,11~.0~1,6~]tetradec-3-ene-5,9,12,13,14-pentol
Mass : 319.270
229828
(+/-)-tetrodotoxin
Mass : 319.270
209255
Anhydrotetrodotoxin
Mass : 301.255
221694
tetrodotoxin is a Conjugate Base of
tetrodotoxin(1+)
Mass : 320.277
Formula : C11H18N3O8
180459
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