In order to use clipping and masking in web design, it is essential to understand the syntax and properties of CSS, SVG, and canvas. Additionally, you need to take into account the browser support, compatibility, and fallback options for each technique. For example, with CSS, you can use the clip-path property that takes a shape or a path as a value, or the clip property which takes a rectangle as a value (although this is deprecated). To mask an element with CSS, you can use the mask-image property which takes an image or a gradient as a value, or the mask property which is a shorthand for several mask-related properties. With SVG, you can use <clipPath> or <mask> elements to define clipping or masking regions and then reference them with the clip-path or mask attributes on the target element. Lastly, with canvas you can use context.clip() or context.globalCompositeOperation methods to define clipping or masking operations and then draw shapes or images that you want to clip or mask on the canvas.