Arc Institute

Want to start your own lab out of grad school? Our Science Fellow program gives you a springboard to launch your independent career! https://lnkd.in/gjDn-aBb As a Science Fellow, you’ll enjoy: 💸Unrestricted funding to support your research and a team of 2-4 people 🧪Freedom to pursue curiosity-driven research 🤝Opportunities for cross-discipline collaboration 🔬Robust scientific infrastructure and access to cutting edge Technology Centers So far, Arc has welcomed 2 Science Fellows, Jingtian Zhou and Uche Medoh, PhD, who have already started building their research programs in quantitative modeling of gene expression dynamics and discovering metaboprotein therapeutics for age-related diseases, respectively. Arc is accepting applications for our next Science Fellow to start their lab in 2025. This year, we are looking for an exceptional scientist conducting research in Neurobiology or Immunology to join Arc. Individuals receiving their PhD, MD, or MD/PhD between spring 2023 and summer 2025 are eligible to apply. Make sure to apply by January 15, 2025! https://lnkd.in/gkBGe-tT Want to learn more? Join Arc co-founder and Core Investigator Dr. Patrick Hsu for a virtual Information Session and Q&A on Friday, December 6, from 10-11am PST. Register here: https://lnkd.in/gATbGvHg

Are you excited to join a scientific community that enables you to pursue your most innovative ideas? Applications for our Core Investigator, Science Fellow, and Innovation Investigator searches are open! https://lnkd.in/gh3tBsNH What does it mean to be an Arc faculty or fellow? 💸 Guaranteed, annual, no-strings attached funding for you and your lab 🔓 Autonomy to pursue your boldest research 🔬 Access to cutting-edge equipment and technologies through collaborations with Arc’s Technology Centers 🤝 Engagement with an innovative group of scientists across Stanford University, University of California, Berkeley and University of California, San Francisco. This cycle, we’re conducting five searches for new faculty and fellows to join our community: We’re thrilled to partner with Stanford University and University of California, San Francisco for two Core Investigator searches. With Stanford’s Department of Bioengineering, we’re looking for a senior faculty (Associate or Full Professor) leading the field in computational biology/machine learning, neurobiology, or immunology. https://lnkd.in/gFCid7-n With UCSF’s Department of Neurology, we’re seeking a scientist (open rank) aspiring to groundbreaking research in neurobiology or neuroimmunology. https://lnkd.in/ge8pKVig For current faculty at Stanford University, University of California, Berkeley, and University of California, San Francisco with a focus on neurobiology, immunology, or machine learning there are two ways to join the Arc community. We are looking to grow our Innovation Investigator community, where you receive unrestricted funding over 5 years to pursue your boldest ideas. https://lnkd.in/gRS6XeyG Arc also welcomes applications from faculty to our Core Investigator program, where you keep your faculty appointment AND benefit from everything running a lab at Arc has to offer. https://lnkd.in/gn5Qua5W We additionally plan to welcome an early-career scientist (PhD, MD, or MD/PhD who graduated in 2023-2025) ready to launch their own lab at Arc in immunology or neurobiology through our Science Fellows program. https://lnkd.in/gkBGe-tT At Arc, we believe great science happens when creative minds can pursue their boldest ideas. We encourage researchers excited to engage with Arc’s research mission, model, and community to apply!

Are you excited to join a scientific community that enables you to pursue your most innovative ideas? Applications for our Core Investigator, Science Fellow, and Innovation Investigator searches are open! https://lnkd.in/gh3tBsNH What does it mean to be an Arc faculty or fellow? 💸 Guaranteed, annual, no-strings attached funding for you and your lab 🔓 Autonomy to pursue your boldest research 🔬 Access to cutting-edge equipment and technologies through collaborations with Arc’s Technology Centers 🤝 Engagement with an innovative group of scientists across Stanford University, University of California, Berkeley and University of California, San Francisco. This cycle, we’re conducting five searches for new faculty and fellows to join our community: We’re thrilled to partner with Stanford University and University of California, San Francisco for two Core Investigator searches. With Stanford’s Department of Bioengineering, we’re looking for a senior faculty (Associate or Full Professor) leading the field in computational biology/machine learning, neurobiology, or immunology. https://lnkd.in/gFCid7-n With UCSF’s Department of Neurology, we’re seeking a scientist (open rank) aspiring to groundbreaking research in neurobiology or neuroimmunology. https://lnkd.in/ge8pKVig For current faculty at Stanford University, University of California, Berkeley, and University of California, San Francisco with a focus on neurobiology, immunology, or machine learning there are two ways to join the Arc community. We are looking to grow our Innovation Investigator community, where you receive unrestricted funding over 5 years to pursue your boldest ideas. https://lnkd.in/gRS6XeyG Arc also welcomes applications from faculty to our Core Investigator program, where you keep your faculty appointment AND benefit from everything running a lab at Arc has to offer. https://lnkd.in/gn5Qua5W We additionally plan to welcome an early-career scientist (PhD, MD, or MD/PhD who graduated in 2023-2025) ready to launch their own lab at Arc in immunology or neurobiology through our Science Fellows program. https://lnkd.in/gkBGe-tT At Arc, we believe great science happens when creative minds can pursue their boldest ideas. We encourage researchers excited to engage with Arc’s research mission, model, and community to apply!

🧬 Evo, the first foundation model trained at scale on DNA, is a Rosetta Stone for biology. DNA, RNA, and proteins are the fundamental molecules of life—and cracking the code of their complex language is an ongoing grand challenge. 🔬 Today in Science Magazine, the labs of Arc Innovation Investigator Brian Hie and Arc Co-Founder Patrick Hsu explain how Evo captures two fundamental aspects of biology: the multi-modality of the central dogma and the multi-scale nature of evolution. Evo excels at prediction and generation tasks across all of these molecules and their interactions. An exciting example of what Evo can do: the team used it to design a totally new CRISPR system, including a guide RNA that makes Cas9 cut even better. Evo can also design DNA sequences over one million base pairs in length, reaching the size of many real genomes. 🧠 Check out the paper now in Science: https://lnkd.in/gXNd6pT9

A new generation of young scientists trained in top CRISPR labs are leading the charge in gene editing. Among them are 10 U.S.-based researchers including... 🧑🔬 Jonathan Gootenberg & Omar Abudayyeh, Molecular engineers, Harvard Medical School - These two do almost everything together, including running their own joint lab at Harvard Med focused on developing tools capable of tackling some of the field’s toughest problems. 🧑🔬 Patrick Hsu, Assistant professor of bioengineering, University of California, Berkeley; Co-founder, Arc Institute - Hsu has become a leader in merging machine intelligence with biology to mine for and design new CRISPR systems. 🧑🔬 Britt Adamson, Assistant professor of molecular biology, Princeton University - Since starting her own lab at Princeton, Adamson has continued to develop cutting-edge genomics tools, both for screening and editing. 🧑🔬 Alex Marson, Director, Gladstone-UCSF Institute of Genomic Immunology (Gladstone Institutes); and scientific director of human health, Innovative Genomics Institute - Marson has worked out ways to deliver CRISPR systems to specific cell types in vivo, using a combination of antibodies and cell-penetrating peptides. 🧑🔬 Krishanu Saha, Associate professor of biomedical engineering and medical history and bioethics, University of Wisconsin-Madison - Saha is leading a five-year, $29 million NIH project to develop CRISPR-based treatments for two inherited eye conditions that cause blindness. See the full list and read more about these scientists here: https://trib.al/E43HhhF #science #geneediting #CRISPR #research #genetics

We are thrilled Dave Burke is joining us as Chief Technology Officer as we forge ahead at the interface of biology and AI to build a computational model of the cell. Dave most recently led Android engineering as VP Engineering at Google Dave will also keep his hand in at Google advising on special projects there. We are excited to have a leader who has scaled Android to nearly half of humanity… to say nothing of his PhD in biomedical engineering. Welcome to Arc, Dave! We’ve got work to do!

Arc was founded so that brilliant minds can pursue their boldest ideas. Today, our newest Investigators and Awardees join the Arc community. These exceptional scientists are pioneering research into critical questions about complex human disease. Join us in welcoming: 🧑🔬Core Investigators Felix Horns, Isha Jain, and Christoph Thaiss 🔬Science Fellow Uche Medoh, PhD 🦠Innovation Investigators Maayan Levy and Theo Roth 💥Ignite Award recipient Will Allen. We’re also excited to let you know that our 2025 faculty search applications are now open! Core Investigator candidates can apply now through coordinated searches with University of California, San Francisco, Department of Neurology or Stanford University Bioengineering Department, or through our open call! Potential Science Fellows and Innovation Investigators may apply through our open searches: https://lnkd.in/gCcPc-yh Head to our blog for more on our new scientists: https://lnkd.in/gqyb4fg8

Exciting collaborations old and new are flourishing at our first Investigator Retreat. Thank you Hani Goodarzi, Chun Jimmie Ye, Xiaojie Qiu, Silvana Konermann, Patrick Hsu, Jingtian Zhou, Luke Gilbert, Andrew Yang, Anna Molofsky, Nathanael Gray, Alanna Schepartz, Isha Jain, and William Greenleaf for sharing your progress yesterday and sparking new ideas. See everyone next year!

It’s not often we catch all of our Core Investigators in one place, standing still, but we did it! Welcome Dr. Felix Horns - Patrick Hsu, Silvana Konermann, Lingyin Li, Luke Gilbert, Hani Goodarzi and Arc Science Fellows Uche Medoh, PhD and Jingtian Zhou are glad you're here.

🎉 Today, Arc welcomes our newest Core Investigator, Dr. Felix Horns! Dr. Horns joins the Arc community as a Core Investigator and Stanford University School of Medicine as Assistant Professor of Genetics. The Horns lab works at the interface of synthetic biology and genomics to discover the fundamental principles governing how cells and tissues operate, particularly within the immune system and the brain. At Arc, the Horns lab will create and apply new technologies for monitoring and manipulating living cells, shedding light into how cells change over time and how therapeutics could be delivered directly to cells within the body. Welcome to Arc, Dr. Horns! 🥼