History of Medicine

Harnessing Gallic Acid & Resveratrol to Combat Triple-Negative Breast Cancer A new study highlights the potential of plant-derived compounds, gallic acid (GA) and resveratrol, in targeting triple-negative breast cancer (TNBC). Unlike conventional therapies, which often face challenges like drug resistance, this multi-target approach explores molecular docking with TNBC-associated receptors such as HER2, ER, PR, and BRCA1. 🧬 Why it matters: TNBC is one of the most aggressive breast cancer subtypes. Synergistic, less toxic alternatives are crucial to reducing recurrence and metastasis. 📖 DOI: https://lnkd.in/ehtM6tza #BreastCancerResearch #TripleNegativeBreastCancer #GallicAcid #Resveratrol #CancerTherapies

🌟 Evaluating Functional Outcomes in Clavicle Midshaft Fracture Repair 🌟 A recent study explores the effectiveness of plate fixation for displaced midshaft clavicle fractures, focusing on union rates, functional outcomes, and potential complications. Authored by Naeem Hussain and colleagues, this research assessed 20 patients between January and July 2024 using the Oxford Shoulder Score and radiological data. Results revealed: ✅ 75% achieved outstanding functional outcomes ✅ 15% reported good outcomes ✅ 10% experienced fair outcomes ⚠️ Minimal complications, such as plate prominence and hypertrophied scars, were noted. 📄 Published in History of Medicine (Vol. 10, No. 2, 2024, pp. 1849–1855). 🔗 https://lnkd.in/ekVm5P8u This study reinforces the reliability of surgical plating in enhancing recovery for clavicle fractures. #OrthopedicResearch #ClavicleFractures #PlateFixation #FunctionalOutcomes #HOM

🚨 Antibiotic Resistance in Salmonella typhimurium: Insights from Poultry and Goat Farms in Punjab, Pakistan 🚨 Antibiotic resistance in Salmonella typhimurium is a growing concern, especially in the context of poultry and livestock farming. This study by Iqra Asghar, Shazia Asghar, Fouzia Tanveer, @Hafiza Fizzah Riaz, @Yasir Nawaz, @Aayza Ashar, @Farman Ullah, @Muhammad Luqman, @Abdul Quyyum Mirza, and @Muhammad Thouseef examines the prevalence of Salmonella in chickens and goats, highlighting crucial antibiotic resistance trends. 🔑 Key Insights: Salmonella typhimurium found in both goats and chickens poses significant health risks. Antibiotics like Nitrofurantoin, Ceftazidime, and Ofloxacin show varying degrees of effectiveness in treating infections. Oxacillin and Ceftazidime should be used with caution due to resistance patterns. Overuse of antibiotics in animal farming has serious consequences for human health. These findings call for more stringent controls on antibiotic use in agriculture to prevent further resistance development. 📖 Dive into the full article here: https://lnkd.in/e5h8DZCs What actions can we take to curb antibiotic resistance in animal farming? Share your thoughts! #AntibioticResistance #AnimalHealth #FoodSafety #PoultryFarming #Research #PublicHealth

💙 Behavior Modification After a Heart Attack: Insights From Patients and Healthcare Professionals 💙 How can heart attack survivors be empowered to make lasting behavior changes that reduce the risk of future cardiac events? This insightful study by @Adnan Yaqoob and colleagues sheds light on patients' experiences and healthcare professionals' perspectives on behavior change post-myocardial infarction. Through in-depth qualitative research, the study identifies key themes: 1️⃣ The journey of behavior modification after a heart attack 2️⃣ Motivations driving change 3️⃣ Skepticism about the impact of behavior change 4️⃣ Challenges patients face in adopting new habits The findings emphasize the need for evidence-based behavior modification programs in routine clinical practices and cardiac rehabilitation to improve long-term outcomes and patient well-being. 📖 Read the full article here: https://lnkd.in/eRhXvdbt Let’s discuss: How can healthcare systems better support behavior change among cardiac patients? Share your thoughts below! #BehaviorModification #CardiacRehabilitation #PsychosocialHealth #HealthCareInnovation #AcademicPublishing #HOM

🌍 Prevalence of Diseases Among School-Going Children: Key Insights from Okara District 🏫✨ 📊 A recent study highlights the health challenges faced by school children in Okara District, Pakistan. Researchers assessed the prevalence of communicable and non-communicable diseases among students in public and private schools, uncovering crucial data that demands attention. 🔍 Key Findings: Out of 962 students surveyed, 16.21% were affected by communicable diseases. 22.14% had non-communicable diseases. Children aged 6–12 years were significantly impacted, raising concerns for early interventions. Analysis using ANOVA and Chi-square tests confirmed notable differences in disease distribution. Full Article: https://lnkd.in/dFKi69cq 📌 This retrospective study sheds light on the critical role of parental awareness and school-based healthcare in mitigating risks. Let’s prioritize children’s health and build a healthier future! 💪🌟 #ChildHealth #PublicHealth #SchoolWellness #DiseasePrevalence #GlobalHealth #IJPR

🧠 Understanding Gliomas: IDH Mutations as a Game-Changer 🧬 Our research team is proud to present a groundbreaking study on the frequency of isocitrate dehydrogenase (IDH) mutations in glioma patients at Hayatabad Medical Complex (HMC), Peshawar. Authors: Muhammad Ibrahim Afridi (Principal and Corresponding Author), Resident Neurosurgery, Hayatabad Medical Complex (HMC), Peshawar. Sonia Umar Afridi, Ph.D. Scholar in Anatomy, Khyber Girls Medical College, Peshawar. Dr. Sohaib Ali, Resident Neurosurgery, HMC, Peshawar. Tauseef Ullah, Resident Neurosurgery, HMC, Peshawar. 🔍 Why this matters: IDH mutations are pivotal biomarkers that not only improve glioma diagnosis but also influence treatment outcomes and survival rates. This study reveals: 57% of glioma cases showed IDH mutations. Mutations were most prevalent in Grades 2 and 4 gliomas, with statistically significant differences across age groups and grades. This work highlights the crucial role of genetic analysis in advancing neuro-oncology and offering patients personalized care. 📄 Dive deeper: Read our findings in History of Medicine 👉 https://lnkd.in/ehXMn5B5 We welcome collaborations and conversations! Let’s work together to push the boundaries of brain tumor research. #Gliomas #IDHMutations #Neurosurgery #MedicalResearch #BrainTumors #Collaboration

🌟 Call for Papers: History of Medicine (ISSN 2409-5583) 🌟 We are now accepting submissions that delve into the fascinating journey of medicine through the ages. Topics of interest include: 🩺 Ancient medical practices 📜 Influential figures and breakthroughs 🌍 Traditional healing systems ⚖️ Medical ethics in history 🎨 Medicine in art and literature Submit Article: https://lnkd.in/e2FY6Gke Join us in uncovering how the past shapes the future of medicine! 💡 #HistoryOfMedicine #CallForPapers #MedicalHistory #ResearchOpportunity

💡 Improving Healthcare Access and Satisfaction in Lahore: A Study on Sehat Insaf Card Muhammad Hamza Taufeeq, @Sayyad Ali, @Syed Alauddin, Ismail Jadoon, Mudassir Khattak, Jamil UrRahman, Mian Shahzeb Haroon, and Tawseef Ahmad's study assesses the utilization of the Sehat Insaf Card and patient satisfaction with the Sehat Sahulat Program in Lahore, Pakistan. Key Findings: ✔️ Majority of participants were young men (77%, ages 21-25). ✔️ 88% awareness of the program's benefits, but 62% unaware of ambulance fees. ✔️ Satisfaction rates: 54% with hospital staff, 58% with doctors, and 31% with hospital conditions. ✔️ Private vs. public hospitals showed significant satisfaction differences (p=0.017). Conclusion: While the Sehat Sahulat Program improves access to healthcare, addressing gaps in knowledge and service quality can further enhance its impact. 📖 Corresponding Author: @Tawseef Ahmad (tausifsafi95@gmail.com) #HealthcareAccess #SehatInsafCard #PatientSatisfaction #SehatSahulatProgram #PakistanHealthCare

🌟 Exploring the Genetic Mysteries of Dandy-Walker Syndrome 🌟 We are excited to share the remarkable research "Unveiling the Molecular Landscape of Dandy-Walker Syndrome" by Dr Arslan wajid, Muhammad Adnan Shahid, Amina Arif, @Muhammad Ajmal, and their esteemed collaborators. This groundbreaking study investigates the genetic factors contributing to Dandy-Walker Syndrome (DWM), a rare neurodevelopmental condition affecting 1 in 5000 live births. Key insights include: 🔬 The role of chromosomal anomalies, duplications, and de novo mutations in the development of DWM. 🧬 Identification of critical genetic loci (3q24 and 6p25.3) and their association with cerebellar granule neuron precursors (GNPs). 📈 A call for Whole Exome Sequencing (WES) to uncover unexplored pathogenic variants. This work deepens our understanding of DWM and paves the way for advanced molecular diagnostics. For a closer look: https://lnkd.in/ejqSxxg2 Let’s celebrate these strides in genetics and neurodevelopmental research! 🚀 #DandyWalkerSyndrome #GeneticResearch #Neurodevelopment #MolecularBiology #ScienceCollaboration #HOM #HistoryofMedicine

🧠 Elongation Techniques vs. Sub-Occipital Muscle Inhibition: Treating Text Neck Syndrome 📱 A collaborative study by a team of expert physiotherapists sheds light on effective treatments for text neck syndrome, a growing concern due to excessive mobile device use. 👩🔬 Authors: @Raiqa Rafique (Bhatti Hospital, Kasur) @Hafiza Noor (Al-Noor Physiotherapy Clinic, Faisalabad) Muhammad sohaib Roomi (Khairpur Institute of Physiotherapy) Mahnoor Shehzadi (Master’s in Advanced Physiotherapy) Dr. Muneeba Najeeb (CMH Lahore Medical College) @Maryam Shahzadi (University of Lahore) Dr Mahrukh PT (GCU Faisalabad) Muhammad Assad Abbas Bajwa (Corresponding Author, GCU Faisalabad) 🔍 Key Findings: ELDOA technique showed greater effectiveness in reducing pain and disability compared to the sub-occipital muscle inhibition technique. The study highlights innovative physiotherapy approaches for tech-related health issues. Full length Article: #TextNeck #Physiotherapy #HealthResearch #ELDOA #PainManagement