IHI-PROMINENT

We're proud to announce a new Innovative Health Initiative (IHI) funded IHI-PROMINENT publication! Our recent study in Alzheimer's Research & Therapy explains how a stepwise, data-driven approach can enhance dementia diagnostics. Using the Clinical Decision Support System (CDSS) by Combinostics, streamlines diagnostic pathways for syndrome diagnosis, identifying dementia etiology, and determining eligibility for disease-modifying therapies. Key findings include: The tools helps to efficiently reduce unnecessary testing while maintaining diagnostic accuracy. It supports clinicians in selecting the most relevant diagnostic tools. This contributes to ensure that patients will receive more timely and accessible diagnoses in future. 👉 Read the full paper: https://lnkd.in/eqCw5sHy Congratulations to the authors: Aniek van Gils, Antti Tolonen, Argonde van Harten, Sinthujah Vigneswaran, Frederik Barkhof, Leonie (N.C.) Visser, Juha Koikkalainen, Sanna-Kaisa Herukka, Steen Gregers Hasselbalch, Patrizia Mecocci, Anne Remes, Hilkka Soininen, Afina Lemstra, Charlotte Teunissen, Linus Jönsson, Jyrki Lötjönen, Wiesje van der Flier & Hanneke Rhodius- Meester

** paper alert! ** https://lnkd.in/defKuBqR Aniek van Gils published a data-driven approach to efficiently guide stepwise diagnostic testing for three clinical scenarios: 1) syndrome diagnosis, 2) etiological diagnosis, and 3) eligibility for DMT. Using a digital cognitive test cCOG, as prescreener, and a AI based classfier, we were able to create accurate and efficient diagnostic pathways. As such, a data-driven tool holds promise for assisting clinicians in selecting tests of added value across different clinical contexts. This becomes especially important with DMT availability, where the need for more efficient diagnostic pathways is crucial to maintain the accessibility and affordability of dementia diagnoses. In IHI-PROMINENT we will test this approach clinically. Many thanks to all co-authors for a great collaboration: Antti Tolonen, Argonde van Harten, Sinthujah Vigneswaran, Frederik Barkhof, Leonie (N.C.) Visser, Juha Koikkalainen, Patrizia Mecocci, Hilkka Soininen, Evelien Lemstra, Charlotte Teunissen, Linus Jönsson, Wiesje van der Flier, Amsterdam UMC - Alzheimercentrum Amsterdam And to ZonMw: Geestelijke gezondheid (ggz) for supporting this work through a Memorabel grant 4D-FUTURE

🌟 Event Highlight: The Innovative Health Initiative (IHI) funded IHI-PROMINENT consortium meeting in Barcelona. 🌟UEF Brain Research Unit | UEF Aivotutkimusyksikkö representatives director Eino Solje and coordinator Kaisa Paldanius had the privilege of attending the IHI-Prominent event held in Barcelona this November. This gathering brought together IHI-PROMINENT partner organizations in #health #innovation and #research, fostering #collaboration and sharing groundbreaking advancements. The event was a testament to the power of interdisciplinary cooperation in driving forward scientific discovery and innovation. University of Eastern Finland UEF Brain Research Unit | UEF Aivotutkimusyksikkö is a partner in IHI-PROMINENT consortium and it is led by professor Alina Solomon from UEF part. #IHIProminent2024 #HealthInnovation #Neuroscience #UEFBrainResearch #ScientificCollaboration #teamwork

🌟 Event Highlight: The Innovative Health Initiative (IHI) funded IHI-PROMINENT consortium meeting in Barcelona. 🌟It was a pleasure to represent the UEF Brain Research Unit | UEF Aivotutkimusyksikkö together with Eino Solje in the IHI-Prominent gathering, which brought together IHI-PROMINENT partner organizations in #health #innovation and #research, fostering #collaboration and sharing groundbreaking advancements. 🧠 University of Eastern Finland UEF Brain Research Unit | UEF Aivotutkimusyksikkö is a partner in IHI-PROMINENT consortium and it is led by professor Alina Solomon from UEF part. 🔗 Read more about Precision medicine in #neurodegeneration IHI-PROMINENT project https://lnkd.in/eQJEmu6j #IHIProminent2024 #HealthInnovation #Neuroscience #UEFBrainResearch #ScientificCollaboration #teamwork #ClinicalStudies

The Innovative Health Initiative (IHI) funded IHI-PROMINENT consortium held its 2nd Annual Meeting on 20–21 November in Barcelona, hosted by Fundación Pasqual Maragall. Representatives from all 18 partner organisations reviewed progress and planned the next steps for precision medicine in neurodegenerative diseases. Key updates included prediction models, diagnostic algorithms, digital platform validation, and Public Involvement. Presentations also covered real-world evidence, anti-amyloid therapies, and project milestones https://lnkd.in/eKtrPJTF

The Innovative Health Initiative (IHI) funded IHI-PROMINENT consortium held its 2nd Annual Meeting on 20–21 November in Barcelona, hosted by Fundación Pasqual Maragall. Representatives from all 18 partner organisations reviewed progress and planned the next steps for precision medicine in neurodegenerative diseases. Key updates included prediction models, diagnostic algorithms, digital platform validation, and Public Involvement. Presentations also covered real-world evidence, anti-amyloid therapies, and project milestones https://lnkd.in/eKtrPJTF

Our IHI-PROMINENT consortium, funded by the Innovative Health Initiative (IHI), held its 2nd Annual Meeting on 20–21 November in Barcelona (Spain), hosted by Fundación Pasqual Maragall. Representatives from all 18 partners discussed progress and next steps for precision medicine in neurodegenerative diseases. Key updates included prediction models, diagnostic tools, digital platform validation, real-world evidence, anti-amyloid therapies & Public Involvement. Read more about the meeting’s highlights: https://lnkd.in/eB-YQ_hS

🙏 Thank you BarcelonaBeta Brain Research Center Fundación Pasqual Maragall for hosting a very productive consortium meeting for the IHI-PROMINENT project. It was great hearing the progress made across work packages and having many valuable conversation with the other partners! ℹ️ IHI-PROMINENT, is a European collaborative project in precision medicine and neurodegenerative diseases with the goal of creating a digital platform for better diagnostics and treatment. IHE - The Swedish Institute for Health Economics leads the part of the project that aims at designing, implementing, and evaluating a process to gather real-world evidence from the digital platform for the evaluation of new technologies.  

The IHI-PROMINENT Management Team, led by our colleague Andrea Martí del Rio from SYNAPSE and Anna Hansson from Karolinska Institutet, works to integrate efforts across all work packages and ensure proper progress of the project, including good internal communication tools to facilitate work dynamics. More information about the project: 👉 ihi-prominent.eu

The second day of our Innovative Health Initiative (IHI)funded IHI-PROMINENT consortium meeting started with a presentation by Sofie Persson (IHE - The Swedish Institute for Health Economics) about real-world evidence for new health technologies. This was followed by Lena Sannemann who spoke about the implementation, evaluation and validation studies that will be conducted to ensure that our digital platform meets the needs of both specialists as well as patients. Next, we discussed the private sector contributions in PROMINENT with a presentation by Lennart Thurfjell (Combinostics). Before moving onto our networking coffee break we took a nice group photo at the beautiful premises of Fundación Pasqual Maragall. Shortly after, Christophe Bintener (Alzheimer Europe) presented on the communication activities, followed by Sebastien Libert (Alzheimer Europe) introducing the work on Public Involvement. Last but definitely not least, our excellent Project Managers Andrea Martí del Rio (SYNAPSE Research Management Partners) and Anna Hansson (Karolinska Institutet) presented on the management aspects of the project, noting that the consortium is well aligned with the planned timeline and deliverables. We'd like to thank all consortium members for their great contributions and wish them safe travels home!