Institute for Protein Innovation

Throwback to our fall platform retreat in Essex Woods. We’re feeling especially grateful this week that we get to do science with such smart and hilarious colleagues!

The Baker Lab at the Institute for Protein Design, University of Washington, recently hosted this powerful webinar on computational protein design. Take a journey through the history of this groundbreaking field, guided by some of the greats!

The brain is full of mysteries — like how glypican proteins act in axon guidance, synapse organization and neuron migration. “They regulate so many processes … we’ve only seen the tip of the iceberg,” says Daniel Del Toro Ruiz of the Universitat de Barcelona. Read more about this enigmatic protein family in our latest blog ➡️ https://lnkd.in/etjhY_7u

Nature did a great job capturing both the problems and potential solutions in finding and developing reliable, reproducible antibodies. We’re happy to be part of the article. Read it here!

Antibody alert 📣📣 We’ve released new recombinant antibodies targeting glypican family members GPC1, GPC3 and GPC4! Browse our collection & order today! https://lnkd.in/e-ShaHM3

We hosted our first antibody workshop on our Neurexin/Neuroligin panel today! It was great to see our collaborator data using our beta-stage rAbs & hear research updates related to planar cell polarity, extracellular vesicle markers, synapse formation, axon guidance and more. Interested in joining us for future neurobiology target workshops? Email antibodies@proteininnovation.org for more information! Thanks Tabrez Siddiqui, Luís Ribeiro, Karl Murray, Dima Ter-Ovanesyan, Yimin Zou, Xin Yu, Rob Meijers, Mike Walden!

A big welcome to Marcus Sandaire, who recently joined us as a research associate! At IPI, he conducts quality control of recombinant antibodies using liquid chromatography-mass spectrometry. A recent graduate of the University of Massachusetts, Boston, with a bachelor’s in biochemistry, Marcus brings hands-on experience from an internship at Merck and research in Daniel Dowling’s lab at UMass Boston. He’s excited to contribute to IPI’s cutting-edge research and collaborate with a team passionate about antibody discovery. Outside of the lab, Marcus enjoys watching soccer and sharpening his chess skills. We’re happy to have him on the team!

Virtual seminar alert 📣📣 Tomorrow at 2 p.m. ET Sean J. of New England Biolabs joins us for an #IPISeminar on how to use computational methods to explore the natural and non-natural protein space. Find the link on our events calendar ➡️

Deborah Moshinsky's no-stone-left-unturned approach to quality control is raising the bar for antibody production at IPI, and in the wider the antibody reagent space. Find out more about her story and how she’s bettering IPI ➡️ https://lnkd.in/eEk2Dr3d

Take a look at this wonderfully comprehensive video from Quanta Magazine! Shows the significance of advances in computational protein design and protein structure prediction, as recognized with the 2024 Nobel Prize in Chemistry!