ISOS Project EU

✨ 𝐏𝐚𝐫𝐭𝐧𝐞𝐫 𝐒𝐩𝐨𝐭𝐥𝐢𝐠𝐡𝐭: 𝐅𝐫𝐚𝐮𝐧𝐡𝐨𝐟𝐞𝐫 𝐒𝐨𝐜𝐢𝐞𝐭𝐲 (𝐅𝐫𝐚𝐮𝐧𝐡𝐨𝐟𝐞𝐫 𝐈𝐧𝐬𝐭𝐢𝐭𝐮𝐭𝐞 𝐟𝐨𝐫 𝐂𝐞𝐥𝐥 𝐓𝐡𝐞𝐫𝐚𝐩𝐲 𝐚𝐧𝐝 𝐈𝐦𝐦𝐮𝐧𝐨𝐥𝐨𝐠𝐲 𝐈𝐙𝐈) ✨ We are excited to spotlight the 𝐅𝐫𝐚𝐮𝐧𝐡𝐨𝐟𝐞𝐫 𝐒𝐨𝐜𝐢𝐞𝐭𝐲, particularly the 𝐅𝐫𝐚𝐮𝐧𝐡𝐨𝐟𝐞𝐫 𝐈𝐧𝐬𝐭𝐢𝐭𝐮𝐭𝐞 𝐟𝐨𝐫 𝐂𝐞𝐥𝐥 𝐓𝐡𝐞𝐫𝐚𝐩𝐲 𝐚𝐧𝐝 𝐈𝐦𝐦𝐮𝐧𝐨𝐥𝐨𝐠𝐲 𝐈𝐙𝐈 (Fraunhofer IZI), as a key partner in our EU ISOS Project, funded by the prestigious #EICPathfinder! With extensive expertise in 𝐩𝐫𝐨𝐭𝐞𝐢𝐧 𝐚𝐧𝐚𝐥𝐲𝐬𝐢𝐬, 𝐩𝐫𝐨𝐭𝐞𝐨𝐦𝐢𝐜𝐬, 𝐚𝐧𝐝 𝐭𝐡𝐞 𝐝𝐞𝐯𝐞𝐥𝐨𝐩𝐦𝐞𝐧𝐭 𝐚𝐧𝐝 𝐞𝐯𝐚𝐥𝐮𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐛𝐢𝐨𝐦𝐚𝐭𝐞𝐫𝐢𝐚𝐥𝐬, Fraunhofer is leading efforts to 𝐢𝐝𝐞𝐧𝐭𝐢𝐟𝐲 𝐚𝐧𝐝 𝐬𝐞𝐥𝐞𝐜𝐭 𝐭𝐡𝐞 𝐦𝐨𝐬𝐭 𝐭𝐡𝐞𝐫𝐚𝐩𝐞𝐮𝐭𝐢𝐜𝐚𝐥𝐥𝐲 𝐞𝐟𝐟𝐞𝐜𝐭𝐢𝐯𝐞 𝐨𝐟 𝐭𝐡𝐞 𝐝𝐞𝐬𝐢𝐠𝐧𝐞𝐝 𝐩𝐞𝐩𝐭𝐢𝐝𝐞𝐬. Their experience and know-how are crucial in ensuring that our project adheres to rigorous 𝐛𝐢𝐨𝐬𝐚𝐟𝐞𝐭𝐲 𝐬𝐭𝐚𝐧𝐝𝐚𝐫𝐝𝐬, 𝐫𝐞𝐠𝐮𝐥𝐚𝐭𝐨𝐫𝐲 𝐜𝐨𝐦𝐩𝐥𝐢𝐚𝐧𝐜𝐞, 𝐚𝐧𝐝 𝐆𝐋𝐏/𝐆𝐌𝐏 𝐩𝐫𝐚𝐜𝐭𝐢𝐜𝐞𝐬. Through the characterization and selection of effective inhibitors, as well as the analysis of biomaterial-cell and biomaterial-tissue interactions, Fraunhofer plays a vital role in 𝐚𝐬𝐬𝐞𝐬𝐬𝐢𝐧𝐠 𝐭𝐡𝐞 𝐢𝐦𝐩𝐚𝐜𝐭 𝐨𝐟 𝐛𝐢𝐨𝐟𝐮𝐧𝐜𝐭𝐢𝐨𝐧𝐚𝐥𝐢𝐳𝐞𝐝 𝐬𝐜𝐚𝐟𝐟𝐨𝐥𝐝𝐬 𝐨𝐧 𝐭𝐡𝐞𝐫𝐚𝐩𝐞𝐮𝐭𝐢𝐜 𝐨𝐮𝐭𝐜𝐨𝐦𝐞𝐬. Together with Fraunhofer and our consortium, we are committed to 𝐚𝐝𝐯𝐚𝐧𝐜𝐢𝐧𝐠 𝐬𝐚𝐟𝐞 𝐚𝐧𝐝 𝐢𝐧𝐧𝐨𝐯𝐚𝐭𝐢𝐯𝐞 𝐬𝐨𝐥𝐮𝐭𝐢𝐨𝐧𝐬 𝐟𝐨𝐫 𝐭𝐡𝐞 𝐭𝐫𝐞𝐚𝐭𝐦𝐞𝐧𝐭 𝐨𝐟 𝐜𝐡𝐫𝐨𝐧𝐢𝐜 𝐝𝐢𝐬𝐞𝐚𝐬𝐞𝐬. #FranunhoferIZI #HealthcareResearch #Proteomics #InnovationInHealth #protein #ISOS_ProjectEU #EICPathfinder #EUResearch #HorizonEurope

✨ Partner Spotlight: Universitaet Leipzig (ULEI) ✨ We’re excited to introduce Leipzig University (ULEI), a key partner in our ISOS Project EU, funded by the prestigious #EICPathfinder! 📍 ULEI leads the critical work on computer-aided deisgn of anti-VEGF peptides and proteins, leveraging their expertise in #protein and #peptide design to develop innovative solutions for chronic disease treatment. Their work focuses on creating high-affinity binders to block the interaction between VEGF and its receptor, a key factor in diseases like age-related macular degeneration (wAMD). 🔹 Together with ULEI and our consortium partners, we’re pushing the boundaries of personalized medicine and biotechnology to revolutionize chronic disease treatment. #InnovationInHealth #ProteinDesign #PeptideEngineering #Biotechnology #ISOS_ProjectEU #EICPathfinder #EUResearch #HorizonEurope

✨ Partner Spotlight: Universidad Complutense de Madrid (UCM) ✨ We are proud to shine the spotlight on Universidad Complutense de Madrid, a crucial partner in our ISOS Project EU, funded by the prestigious #EICPathfinder! 📍 As one of the most renowned universities in Europe, UCM brings world-class research and expertise to the forefront of our project. UCM leads Work Package 1 (WP1), focusing on in-silico studies and the design of genetically engineered bacteria (GEB) ecosystems in the ISOS Engineered Living Material (ELM). Their team is pioneering innovations in #biomaterials, #ELMs, #microbiology and advanced personalized therapies, playing a pivotal role in developing the groundbreaking technologies for in-situ fabrication and auto-renewed delivery of therapeutic compounds. 🔹 Together with UCM and our consortium partners, we’re revolutionizing chronic disease treatment and driving advancements in personalized medicine and biomedical research. #GeneticEngineering #Microbiology #PersonalizedMedicine #InnovationInHealth #RegenerativeMedicine #ISOSProjectEU #ChronicDiseaseTreatment #EICPathfinder #EUResearch

✨ Partner Spotlight: Silk Biomed SL ✨ We’re excited to introduce Silk Biomed SL (Silk), the Coordinator and a key player in our ISOS Project EU, funded by the prestigious #EICPathfinder! Born from the CTB-UPM Centro de Tecnología Biomédica, Silk Biomed leads in the creation of smart #biomaterials and advanced therapeutic products, based on silk fibroin, stem cells, and genetically-modified bacteria. Their groundbreaking innovations are paving the way for tissue repair and regenerative medicine, delivering safe and innovative solutions to modern healthcare challenges. Together with Silk Biomed and our consortium partners, we’re on a mission to revolutionise chronic disease treatment with cutting-edge biomaterials and genetic engineering. #InnovationInHealth #SilkFibroin #TissueEngineering #RegenerativeMedicine #ISOS_ProjectEU #StemCells #GeneticEngineering #EICPathfinder #EUResearch #GenericallyModifiedBacteria #EuropeanCommission #EUFunding #HorizonEurope

🚀 Driving Innovation with EIC Pathfinder Grant! We are thrilled to announce that our project, ISOS, has been awarded by the European Commission under grant agreement No. 101130454! 🎉 ISOS Project EU aims to revolutionise chronic disease treatment by developing the first biomedical product capable of in-situ fabrication and auto-renewed delivery of therapeutic compounds. Using complex ecosystems of genetically engineered bacteria within a biomaterial-based bioreactor, ISOS will produce therapeutic molecules "on demand", responding directly to the patient's pathological environment. This innovative approach will personalise treatment for conditions like age-related macular degeneration, potentially replacing repeated intraocular injections with a single implantable bioreactor. This groundbreaking project could pave the way for a new generation of therapeutic products, offering personalised treatments with rigorous control of drug production and delivery. We look forward to working with our incredible consortium partners (Silk Biomed SL (Silk), Universidad Complutense de Madrid, Leipzig University, Fraunhofer IZI, Alien Technology Transfer, Northumbria University) to drive this innovation and make a lasting impact on healthcare! 🌍 🔬 💡 🔗 Learn more about the project by visiting our ISOS website, and follow us on LinkedIn and X. https://lnkd.in/eaKgVRQj #EuropeanCommission #EUFunding #HorizonEurope #EIC #PathFinder #ResearchAndInnovation #ISOS #Innovation #BiomedicalResearch #ChronicDiseaseTreatment