I wrote a post about why AI for Biology could eclipse LLMs—and the unique challenges we need to solve to get there. As often I'm the bio person in a circle of LLM researchers in San Francisco, I've had fascinating discussions about AI's future in biology. It's clear we can't simply copy-paste LLM strategies, but the potential impact could be enormous: from understanding life's origins to curing disease. In this post, I break down three critical challenges: - Why we can't just use "RLHF" for biology - Why data quality is more challenging than for LLMs - Why scaling laws alone won't solve our problems - And importantly: what we can do about it. It's not another doom post or hype piece—instead, it's a pragmatic optimist's perspective on building AI for biology. https://lnkd.in/gNYihCKM
Mammoth Biosciences
Biotechnology Research
Brisbane, California 49,429 followers
Improving lives by reading and writing the code of life.
About us
Mammoth Biosciences is a biotechnology company focused on leveraging its proprietary ultracompact CRISPR systems to develop long-term curative therapies, as well as other applications such as decentralized precision diagnostics. Founded by CRISPR pioneer and Nobel laureate Jennifer Doudna and Trevor Martin, Janice Chen, and Lucas Harrington, the company’s ultracompact proteins are designed to enable in vivo gene editing in difficult to reach tissues utilizing both nuclease applications and new editing modalities beyond double stranded breaks, including base editing, gene writing, and epigenetic editing. The company is building out its pipeline of potential in vivo gene editing therapeutics and capabilities and has partnerships with leading pharmaceutical and biotechnology companies to broaden the reach of its innovative and proprietary technology. Mammoth’s deep science and industry experience, along with a robust and differentiated intellectual property portfolio, have enabled the company to further its mission to transform the lives of patients and deliver on the full promise of CRISPR technologies.
- Website
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http://www.mammoth.bio
External link for Mammoth Biosciences
- Industry
- Biotechnology Research
- Company size
- 51-200 employees
- Headquarters
- Brisbane, California
- Type
- Privately Held
- Founded
- 2017
Locations
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Primary
Get directions
1000 Marina Blvd
Suite 600
Brisbane, California 94005, US
Employees at Mammoth Biosciences
Updates
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We are thrilled that California Life Sciences (CLS) has awarded Mammoth the #Pantheon2024 Emerging Innovations Award! Thank you to everyone who voted and shared our story: we're so proud of our innovative work with #CRISPR, and we're very grateful for this recognition from our community for our work.
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We're #hiring a new Director/Senior Director, Regulatory Affairs, Therapeutics in Brisbane, California. Apply today or share this post with your network.
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We're #hiring a new Associate Director / Director - CMC (Chemistry, Manufacturing, and Controls) in Brisbane, California. Apply today or share this post with your network.
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We're #hiring a new Associate Director / Director - CMC (Chemistry, Manufacturing, and Controls) in Brisbane, California. Apply today or share this post with your network.
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We're #hiring a new Associate Director / Director - CMC (Chemistry, Manufacturing, and Controls) in Brisbane, California. Apply today or share this post with your network.
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We're #hiring a new Associate Director / Director - CMC (Chemistry, Manufacturing, and Controls) in Brisbane, California. Apply today or share this post with your network.
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We're #hiring a new Director/Senior Director, Regulatory Affairs, Therapeutics in Brisbane, California. Apply today or share this post with your network.
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We're #hiring a new Director/Senior Director, Regulatory Affairs, Therapeutics in Brisbane, California. Apply today or share this post with your network.
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Today is Familial Chylomicronemia Syndrome (FCS) Awareness Day. FCS is a genetic disease, characterized by severely elevated triglycerides (TG). Mammoth would like to bring your attention to the 3000-5000 patients worldwide who suffer from this life-threatening disease; patients living with FCS face a host of challenges including chronic pain, diabetes, neurocognitive problems, depression, and potentially fatal acute pancreatitis. Strict adherence to an extremely low fat diet may help control the disease, but there are currently no FDA-approved medical treatments for FCS, nor cures. Mammoth is working to provide a one and done treatment for FCS and SHTG #CRISPR #FCSAwareness
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