Serán BioScience

This Thanksgiving, we're grateful for our work, and the friendships we've built with our colleagues, clients and partners. Wishing you an amazing holiday brimming with joy, adventure, and connection! Happy Thanksgiving! #thanksgiving #grattitude

Serán BioScience's approach to development of solid dosage forms enables manufacture of clinical trial materials at virtually any scale, from FIH clinical studies through commercial manufacturing. In this talk, Micah Tuttle, Sr. Engineer in Serán's Product and Process Development group, highlights the importance of flexible and advanceable drug product design to enable rapid clinical development. In this case study, Micah will illustrate how his team applies material sparing approaches and related drug product design to efficiently bring an enabled formulation to the clinic, allowing the dose flexibility required for early phase studies without sacrificing the robust product design expected for a commercial product. Watch the presentation to learn more about the benefits of Serán's Right from the Start® approach: https://hubs.li/Q02Y-ddh0 #efficientdevelopment #idrugproduct #processdesign #CDMO

Serán BioScience is pleased to welcome Drew Lawrence as Business Development Director. Drew brings a diverse background of pharmaceutical experience spanning analytical development, formulation development, process engineering, project management, engineering and operations. Drew will apply his expertise to collaborate with clients, identify their unique program needs, and develop tailored solutions, enabling clients to focus on their core mission—delivering innovative therapies to patients. He holds a degree in Chemical Engineering from UC Santa Barbara. Be sure to say hello when you see Drew out on the tradeshow circuit!

Today, we come together to celebrate and honor everyone who has bravely served in our Nation's military. Your sacrifice, courage, and dedication are deeply appreciated. We also extend our heartfelt gratitude to the families of service members for their unwavering strength and resilience. Your contributions to our country are invaluable, and we thank you wholeheartedly. #veteransday #veterans #thankyou

Be sure to watch this presentation by Dr. Cindy Chung exploring advancements in subcutaneous delivery for high-dose protein therapies. https://hubs.li/Q02XpQ3p0 Traditionally, protein therapeutics are delivered by intravenous infusion due to their low protein concentrations and high-dose requirements, but what if there was an alternative? By utilizing spray drying and particle engineering, we’re exploring high-concentration, stable, solid-state protein suspensions in non-aqueous vehicles to support subcutaneous administration—even at ultra-high concentrations. 🌟 Key Learnings: • Spray dried protein suspensions are a viable pathway to achieving high-dose subcutaneous formulations (> 400 mg/mL) • Particle property optimization enables efficient delivery at these concentrations • High-concentration bevacizumab suspensions demonstrate stability for 6+ months when stored at refrigerated conditions This case study on bevacizumab shows promising results and opens doors to broader applications in mAb therapy delivery. If you're working on protein therapeutics or delivery innovations, you won’t want to miss this! Connect with us and learn more at Serán BioScience. #ProteinTherapeutics #DrugDelivery #SprayDrying #FormulationDevelopment #SubcutaneousDelivery #BiopharmaInnovation

Looking for an outsourcing partner who specializes in developing versatile solid dosage forms? Serán BioScience's team offers expertise in development and production of capsules, tablets, powder-in-bottle formulations, and a wide variety of other engineered solutions tailored for optimal in vivo exposure and scalability from discovery to clinical trials. Serán's solid dosage forms are engineered for a wide range of formulation approaches such as overcoming solubility challenges and to enable extended-release. Connect with us to learn how Serán's experienced dosage form team can help bring your drug to market quickly and reliably. https://hubs.li/Q02WV4Ql0 #tabletdesign #cdmo #clinicaltrial #dosageform

Join Serán BioScience's team at Partnerships Opportunities in Drug Delivery (PODD) Oct. 28-29th. Serán's subject matter experts will be on hand and eager to hear about your latest innovations and drug development challenges. Mark Kastantin, PhD will present on spray drying to overcome cold storage of RNA-loaded LNPs. The results show that careful formulation of solid-state LNPs manufactured vis spray drying can provide a scalable path to more widely available LNP-based nucleic acid therapies with improved shelf stability as a dry powder. Jaspreet Arora, Phd will present Seran's approach to rapid clinical development. Serán develops scalable and commercially viable formulations starting at Phase I. Attend each talk to learn more and stop by our table #25 to meet with Mark, Jaspreet and Tanner! #PODD

Join Serán BioScience's team at Partnerships Opportunities in Drug Delivery (PODD) Oct. 28-29th. Serán's subject matter experts will be on hand and eager to hear about your latest innovations and drug development challenges. Mark Kastantin, PhD will present on spray drying to overcome cold storage of RNA-loaded LNPs. The results show that careful formulation of solid-state LNPs manufactured vis spray drying can provide a scalable path to more widely available LNP-based nucleic acid therapies with improved shelf stability as a dry powder. Jaspreet Arora, Phd will present Seran's approach to rapid clinical development. Serán develops scalable and commercially viable formulations starting at Phase I. Attend each talk to learn more and stop by our table #25 to meet with Mark, Jaspreet and Tanner! #PODD

We look forward to seeing you at AAPS this year! Serán BioScience's team is available to meet with you during the conference at booth #2338. Don't miss our expert presentations during the conference! We will have many speaker and poster sessions exploring our team's latest research. See our lineup here: https://hubs.li/Q02TL0tg0 Schedule a meeting with our executive team today: https://hubs.li/Q02TLnFm0 Get in on the debate at our Craft Beer Happy Hour on Tuesday at 3:30. Stop by to weigh-in: Oregon vs. Utah craft beer. #PharmSci360

During AAPS be sure to check out Serán BioScience's lineup of interesting topics presented by our exceptional team of speakers. Serán's SMEs are in the labs and working with our clients every day. Take this opportunity to hear about their innovative research and stop by our booth for live Q&A! Erica Schlesinger, PhD Prologue Title: High Dose SQ Delivery of Protein Therapeutics 2024 PharmSci 360 (https://hubs.li/Q02Tln880) – Online only Wesley Tatum, PhD Rapid Fire Title: Manufacturing and Formulation Impacts on Speciation in Amorphous Solid Dispersion Dosage Forms Poster: Manufacturing and Formulation Impacts on Colloidal Speciation in ASD Dosage Forms Cindy Chung, PhD Rapid Fire Title: High Concentration Protein Suspensions: A Bevacizumab Case Study (>400 mg/mL) Tanner Corrado, PhD Rapid Fire Title: Spray Drying to Overcome Cold Storage of RNA-Loaded Lipid Nanoparticles Quinn Rasmussen Poster Title: Engineering Spray Dried Protein Particles to Enable Subcutaneous Injection of High Concentration Protein Suspensions See more here: https://hubs.li/Q02TlG6R0 Schedule a meeting with our executive team at AAPS today: https://hubs.li/Q02TlHBs0 #PharmSci360