The Alliance for Longevity Initiatives

We congratulate Rep. Brett Guthrie on his appointment as the next Chairman of the House Energy and Commerce Committee and Rep. Frank Pallone on his re-appointment as Ranking Member. We look forward to a busy and impactful two years ahead, as we advocate for the Advanced Approval Pathway for Longevity Medicine and advance our FY26 appropriations priorities to support cutting-edge research and innovation in aging biology!

The bipartisan renewal of the Older Americans Act in the Senate underscores the growing recognition of the challenges and opportunities posed by an aging population. This progress reinforces the importance of continued focus on policies and initiatives led by us at A4LI that prioritize preventative health through aging biology research and aim to increase healthspan, functional well-being, and overall quality of life. We look forward to the House’s decision on this critical bill, as their support would reflect an understanding of the needs of keeping our older population healthy and making healthspan a priority.

Are you interested in the future of aging science? 🌐 NIA is developing its Strategic Directions for Research, 2026-2030 and is seeking public input. By reviewing the draft and providing feedback, you help ensure research goals reflect real-world needs. Explore the 10-goal framework and share your insights by Jan. 31. https://lnkd.in/eYjYMREN #NIHAging #AgingScience #NIH

We are excited to see the following topics be a focus of NIA for the next 5 years. Additionally, the National Advisory Council on Aging advises the Secretary of U.S. Department of Health and Human Services (HHS), Director of The National Institutes of Health, and Director of National Institute on Aging (NIA) on its mission. The Council meets three times a year to consider novel research concepts and recommend funding for promising applications. These are the aging research concepts they approved back in September: https://lnkd.in/gAUDUZjg. Their next meeting, which will be virtual, is scheduled for January 28-29, 2025.

Great news! 🎉 GSK has entered a $45M upfront collaboration with Relation, an AI-powered biotech to identify targets for fibrotic diseases and osteoarthritis. This partnership marks a significant step forward in addressing Relation's first indication, osteoarthritis—a condition that affects millions worldwide. There's so much we still need to learn about osteoarthritis, particularly how it impacts women and men differently. Relation's “Lab-in-the-Loop” platform will leverage human genetics, single-cell multi-omics from human tissue, assays, and machine learning to identify novel targets. Advances like this not only offer hope for better treatments but also pave the way for more personalized approaches that can address these critical disparities. This is exactly the kind of innovation we need to tackle age-related diseases and improve quality of life for everyone. Congratulations Relation and GSK!

I had a great time giving an overview of what we do at A4LI! Thank you for the opportunity Longevity Global!

At the Obesity & Metabolic Innovation Forum today in Boston, BioAge COO & co-founder Eric Morgen, MD will join other biopharma thought leaders in a discussion that explores how combination therapies with the GLP-1 drugs will impact the broader treatment landscape for obesity and related metabolic disorders. BioAge’s lead compound azelaprag is currently in a Phase 2 trial in combination with tirzepatide for obesity. Eric will be joined by Disha Narang, M.D., Dipl of ABOM, CCMS of Endeavor Health, David Tingley of Olio Labs (YC23), and Ginnie (HsiuChiung) Yang of Wave Life Sciences.

It’s Giving Tuesday! We’re thrilled and beyond grateful to announce a generous matching campaign from AgelessRx, which has pledged an annual contribution of $15,000 to help fuel A4LI’s mission of advancing policies that prioritize healthy aging and longevity science. We also sit down with Co-founder and CEO, Anar Isman to discuss his passion for slowing down aging and making longevity science more accessible to the community. Join AgelessRx in supporting us by making a contribution today. Your donation will be matched dollar for dollar, doubling your impact and bringing us closer to a future where longer, healthier lives are a reality for everyone. Your support helps us: ✅ Advocate for policies that accelerate longevity-focused biomedical research. ✅ Raise awareness of the economic and social benefits of healthy aging. ✅ Bring together policymakers, scientists, and advocates to drive meaningful change. Let’s make Giving Tuesday count. Together, we can shape a future where healthy aging is achievable for all. Donate now and double your impact: https://lnkd.in/gsMfyrdE

Happy Thanksgiving! We want to take a moment to express our deepest gratitude to our incredible members and sponsors. Your unwavering support has been the driving force behind A4LI’s mission to advance healthspan and longevity through advocacy and action. Together, we have made strides in bringing longevity science to the forefront of policymaking, fostering critical conversations, and building a community dedicated to reshaping the future of health. From all of us at A4LI, thank you for standing with us every step of the way. As we look ahead to 2025, we're filled with excitement for the opportunities to come. This journey is far from over, and we hope you’ll continue to join us in pushing boundaries and championing the policies that will lead to longer, healthier lives for all. Here's to a bright and transformative new year! Stay safe and stay well! Warm regards, The A4LI Team

A4LI is thrilled to see Jim O'Neill, former CEO of SENS Research Foundation and a long-standing, passionate advocate for longevity science, nominated as Deputy Secretary of Health and Human Services. Jim’s deep interest and extensive experience in the aging biotech and longevity space bring renewed hope for meaningful support and advancements in our revolutionary field of biomedical research. These appointments make it clear that the new administration recognizes the urgent need to address chronic and age-related diseases head-on. The status quo is no longer sufficient when it comes to chronic illness in America, and this team is clearly committed to driving change. At A4LI, we share this vision and stand ready to collaborate on transformative health policies that extend healthy lifespans and improve quality of life for all. We congratulate Jim O’Neill, RFK Jr., Dr. Marty Makary, and Dr. Jay Bhattacharya on their nominations, and we look forward to working with them to help build a healthier future for every American. Jim O’Neill's Nomination Announcement: https://lnkd.in/gM8v9pqh