The Manhattan Street Fund

Akamis Bio, a Cambridge, MA-based clinical-stage oncology company, raised $60M in funding. The company intends to use the funds to support its work to advance NG-350A through a Phase 1b clinical proof-of-concept (PoC) study in patients with locally advanced rectal cancer (LARC). #FundingNews #BiotechFunding #OncologyResearch

Cala Health, a San Mateo, CA-based non-invasive bioelectronic medicine company, raised $50M in funding. The company intends to use the funds to expand operations and its development efforts. #CalaHealth #BioelectronicMedicine #HealthcareInnovation

Ossio, a medical device company based in Woburn, MA, raised $27.6M in equity funding. The company intends to use the funds to increase patient access to metal-free OSSIOfiber® surgical implants. #FundingNews #MedicalDevices #Ossio #EquityFunding 

Adcendo, a Copenhagen, Denmark-based biotech company focused on the development of ADCs for the treatment of cancers with a high unmet medical need, raised $135M in funding. The company intends to use the funds to advance, broaden, and accelerate the development of its ADC pipeline, including the ADCE-T02 (Tissue Factor ADC), ADCE-D01 (uPARAP ADC), ADCE-B05 and A0401 programs. #Biotech #Copenhagen #Denmark #Adcendo 

Zenflow, Inc., a South San Francisco, CA-based medical device company developing a minimally invasive treatment for urinary obstruction caused by enlarged prostate, or benign prostatic hyperplasia (BPH), closed a $24m financing round. The company intends to use the funds for Pre-Market Approval (PMA) submission and preparation for commercialization upon FDA approval of its Spring® System. #ZenflowInc #MedicalDevices #MinimallyInvasiveTreatment 

ZAP Surgical Systems, a San Carlos, CA-based non-invasive robotic brain surgery company, raised $78M in funding. The company intends to use the funds to advance the commercialization of its ZAP-X® Gyroscopic Radiosurgery® platform. #ZAPSurgicalSystems #BrainSurgery 

Protein-Design Startup Archon Adds $20M to Show How ‘Cages’ Can Change Antibody Drugs. Archon Biosciences’ antibody cages change the structure of an antibody to control how a drug distributes in the body. The startup comes from the lab of David Baker, the University of Washington professor of biochemistry recently awarded the Nobel Prize in Chemistry for his work in computational protein design. #ProteinDesign #BiotechStartup #ArchonBiosciences 

PeopleOne Health, a Pittsburgh, PA-based company that specializes in value-based primary care, raised up to $32.3M in funding. The company intends to use the funds to accelerate its growth, enhance its ability to scale operations, invest in talent and technology, and continue innovating its care model. #PeopleOneHealth #HealthcareInnovation 

Seaport Therapeutics, a Boston, MA-based biopharmaceutical company that is developing novel neuropsychiatric medicines, raised $225M in funding. The company intends to use the funds to advance its clinical-stage pipeline of first and best-in-class medicines through important clinical milestones as well as further advance the capabilities of the Glyph™ technology platform. #SeaportTherapeutics #Biopharma #BostonBiotech

Maven Clinic, the world's largest virtual clinic for women's and family health, today announced that it has raised a $125 million in funding. Maven Clinic offers the only global benefit to cover the entire reproductive life cycle on one platform, from preconception and family building to pregnancy, parenting, menopause and midlife. More than 2,000 clients in 175 countries trust Maven to support their employees, including Amazon, Microsoft, AT&T, Morgan Stanley and L'Oreal. #MavenClinic #WomensHealth #FamilyHealth