Manager/Senior Manager, Logistics

The Company

Verve is a clinical-stage genetic medicines company established with a mission to solve the global health epidemic of cardiovascular disease. Founded by world-leading experts in cardiovascular medicine, human genetics and gene-editing, Verve is pioneering a new approach to the care of cardiovascular disease, potentially transforming treatment from chronic management to single-course gene editing medicines. The company’s initial three programs – VERVE-101, VERVE-102, and VERVE-201 – target genes that have been extensively validated as targets for lowering low-density lipoprotein cholesterol (LDL-C), a root cause of cardiovascular disease. VERVE-101 and VERVE-102 are designed to permanently turn off the PCSK9 gene in the liver and are being developed initially for heterozygous familial hypercholesterolemia (HeFH) and ultimately to treat atherosclerotic cardiovascular disease (ASCVD) patients not at goal on oral therapy. VERVE-201 is designed to permanently turn off the ANGPTL3 gene in the liver and is initially being developed for homozygous familial hypercholesterolemia (HoFH) and ultimately to treat patients with refractory hypercholesterolemia. In 2023, Verve was named a Top Place to Work by The Boston Globe for the third consecutive year. Verve is headquartered in Boston, Massachusetts.

The Position

Reporting to the Associate Director, Clinical Supplies & Logistics, the Manager/Sr. Manager, Logistics, will be responsible for providing global logistical support for the end-to-end supply chain for Verve’s gene editing programs, coordinating movement of raw materials, drug substance, drug product, and equipment in support of manufacturing and supply activities at external vendors across various geographies. The candidate must have significant technical experience related to logistics management practices in the pharma/biotech space, with a strong understanding of GxP concepts, cold chain shipping, and global trade regulations related to the import and export of materials across customs borders. The ideal candidate will demonstrate ownership of all shipping activities and will be able to confidently speak to topics related to the Logistics function to both internal and external stakeholders.

Job Responsibilities

• Manage global cold chain logistics:
• Coordinate shipments of GMP and non-GMP bulk and sample material between storage sites, CDMOs, Verve, and CLOs.
• Classify Verve materials for customs and generate necessary customs documentation when needed (e.g. invoices, USDA statements, end use letters etc.).
• Manage relationships with third party logistics partners and customs brokers.
• Coordinate shipping activities with Quality Assurance to ensure material is transferred in a manner compliant with Verve procedures and industry regulations; initiate deviations and CAPAs related to product shipping as required.
• Assess shipping systems for suitability for packout and transport of Verve’s clinical phase production materials.
• Internal logistics infrastructure:
• Ownership of logistics infrastructure by authoring, implementing, and maintaining SOPs related to the function.
• Support implementation of internal ERP inventory management system.
• Represent Technical Operations as the SME for Logistics related to change controls, technology transfers, new vendor introductions, and ad-hoc cross-functional projects.
• Coordinate with internal and external stakeholders on shipping process to proactively implement process improvements to reduce risk and costs and drive efficiencies within supply chain.
• Business support:
• Contract and budget support for logistics service providers and consultants
• Track and coordinate VAT and customs duties spend and reclaims with external vendors.
• Other duties as assigned.

Qualifications

• Bachelor’s degree in a business, scientific, or related field
• 5+ years of experience in a biotechnology or pharmaceutical company (position level dependent on candidate experience)
• Experience interfacing with external contract manufacturing organizations.
• Experience in international and domestic cold chain logistics, specifically within the BioPharma industry. Preference for candidates with experience managing shipment of frozen materials.
• Working knowledge of global customs procedures, including ability to independently research and assign global harmonization codes and an understanding of VAT exposure and reclaim procedures.
• Strong organizational and interpersonal skills with ability to manage activities supporting many different stakeholders, both internal and external.
• Excellent communication skills, with an emphasis on clear, accurate, and detailed verbal and written correspondences.
• Demonstrated ability to competently author GxP compliant documents and reports such as shipping forms, deviations, investigations, and CAPAs is required.
• Knowledge of gene or cell therapy supply chain preferred.
• Experience with commercial shipping validation preferred but not required.
  
  

Don’t check off every box in the requirements listed above? Please consider applying anyway. We want the best candidates for the job, and those candidates don’t always meet 100% of the qualifications listed. At Verve, we are dedicated to building diverse and inclusive teams who embody the values we share: grit, spirit, drive, and passion. We look forward to learning more about your unique background.

EEO Statement

Verve Therapeutics is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.

Recruitment & Staffing Agencies

Verve Therapeutics does not accept agency resumes unless contacted directly by internal Verve Talent Acquisition. Please do not forward resumes to Verve employees or any other company location; Verve Therapeutics is not responsible for any fees related to unsolicited resumes.