ABclonal Technology’s Post

Intracellular protein detection from single cells? With whole transcriptome sequencing and cell surface protein detection? And with full length TCR/BCR sequencing? And sample multiplexing? YES, with Rhapsody platform. Maximise single cell data collection from your precious samples. #singlecellanalysis #multiomics #Immunology #CITE-seq

MTT Assay: Assessing Cell Health in a Snap The MTT assay is a popular tool in cell biology for gauging cellular metabolic activity. This activity indirectly reflects the number of viable cells present, making it a handy assay for: Cell viability: See if your cells are alive and well! Cell proliferation: Monitor cell growth over time. Cytotoxicity: Test the effects of drugs or other agents on cell health. Why it's great: Fast and easy: Get results in a few hours. Quantitative: Measure cell health through a colorimetric readout. High-throughput: Analyze many samples simultaneously. #cellbiology #cytotoxicity #cellproliferation #research

Redefine your CITE-Seq research by expanding its power to intracellular proteins. With our new Intracellular CITE-Seq Assay using BD® AbSeq Antibody-Oligos you can simultaneously detect RNA, surface proteins and intracellular proteins (such as cytokines and transcription factors) to get a full profile of your cells in one experiment like never before. Learn more here: 👉 https://lnkd.in/eUvMfUWT For Research Use Only. Not for use in diagnostic or therapeutic procedures. #IntracellularCITEseq #SingleCellMultiomics #BDRhapsody #BDBiosciences  

Molecular Regulators: Exploring Aladdin's Activin and Inhibin Pathways 🔬 Explore the cornerstone of scientific advancement with Aladdin Biochemical Reagent Company's Activin and Inhibin products! 🌟 Activin and Inhibin are not just proteins; they are essential players in understanding the intricacies of cellular signaling pathways, pivotal for groundbreaking scientific research and drug discovery. From deciphering developmental processes to uncovering potential therapies for diseases like cancer and infertility, Activin and Inhibin hold the key to unlocking new frontiers in biomedical science. Trust Aladdin for premium-grade reagents that fuel innovation and drive progress. Elevate your research today! #AladdinBiochemical #Activin #Inhibin #ScientificResearch #DrugDiscovery #AladdinScientific Aladdin：https://lnkd.in/g6qsm44R

Because What you're missing matters... #WYMM Comprehensive analysis of m6A methylome and transcriptome by nanopore sequencing in clear cell renal carcinoma  Correlation between m6A RNA modification and the progression of clear cell renal cell carcinoma (ccRCC) has been found, however the link between methylation and transcriptional regulation has remained elusive. Here the authors explored this link using direct RNA nanopore sequencing. They identified 5224 dysregulated genes, including four obesity-related genes which could be potential biomarkers for ccRCC. https://lnkd.in/dUpF7Gaz

For over a decade, Applied StemCell has been a trusted partner to scientists, expanding what you can accomplish through iPSCs. Our human iPSC lines are consistently generated and rigorously characterized, providing you with robust tools to advance your disease research, drug discovery studies, and cell-based medicine development. We understand that as a researcher, you need reliability and reproducibility. That’s why our iPSC lines are: - Pluripotency-Validated: Ensuring differentiation potential across all three germ layers. - Genetically Stable: Thoroughly tested to maintain integrity across passages. - Customizable: Tailored to meet the specific demands of your experimental design, including disease-relevant mutations and reporter lines. Whether you're modeling complex diseases or optimizing cell therapy approaches, our iPSCs are the high-quality foundation you need to produce. Join your peers who trust Applied StemCell to deliver the tools they need for cutting-edge discoveries. 👉 Explore our iPSC catalog and custom services: https://lnkd.in/gm3Gi3qF #iPSCResearch #StemCellModels #PhDResearch #DiseaseModeling #RegenerativeMedicine

Glucose transporter 1 (GLUT1) overexpression has been in the news by Crystal Mackall (https://lnkd.in/eFFb74Wp) and Michel Sadelain (https://lnkd.in/eZ4fN9ya). This has shown to increase #potency and #persistence by altering the cells metabolic pathways. Did you know that a simple method to increase GLUT1 expression for #cellandgenetherapy is altering the cell culture environment (mimicking #TME)? It also increases their persistent tumor killing capacity (https://lnkd.in/esAiqeV4). xcellbio bioreactor and Cytek Biosciences spectral FC analysis.

Molecular Regulators: Exploring Aladdin's Activin and Inhibin Pathways 🔬 Explore the cornerstone of scientific advancement with Aladdin Biochemical Reagent Company's Activin and Inhibin products! 🌟 Activin and Inhibin are not just proteins; they are essential players in understanding the intricacies of cellular signaling pathways, pivotal for groundbreaking scientific research and drug discovery. From deciphering developmental processes to uncovering potential therapies for diseases like cancer and infertility, Activin and Inhibin hold the key to unlocking new frontiers in biomedical science. Trust Aladdin for premium-grade reagents that fuel innovation and drive progress. Elevate your research today! #AladdinBiochemical #Activin #Inhibin #ScientificResearch #DrugDiscovery #AladdinScientific

There seems no limit to the number of different Fc variants that antibody engineers are able to produce! A new paper from scientists at The University of Texas Health Science Center at Houston (UTHealth Houston) and University of California, Riverside describes a novel approach to screen Fc variants from CHO libraries to generate variants with improved affinity for FcgRIIa, IIb and IIIa. In particular they focus on a couple of variants that show greatly enhanced ADCC in a PBMC assay. If you are looking to enhance the effector function of your therapeutic antibody this is probably worth a read! DOI: https://lnkd.in/evbpFYkz

#EastMabFocus | Featured Product   💡Driving Innovation in Cell Growth and Differentiation 🔬   Activin A is a member of the TGF-β superfamily and functions as a multifunctional cytokine. Various immune cells, including monocyte-macrophages, mast cells, and certain lymphocytes, can produce Activin A. It performs a wide range of biological functions, such as regulating hematopoietic cell proliferation, promoting neuronal differentiation, modulating pituitary hormone secretion, and supporting tissue repair.   📩 Contact us today to learn more about how our high-quality Activin A can elevate your projects!   #LifeScience #Biotechnology #Biotech #RecombinantProtein #StemCellResearch #CellCulture #Innovation #ActivinA