Ability Biologics’ Post

🌟 Join Us for an Exclusive Webinar! 🌟 Depixus is hosting a webinar on 9/10/24 (9am PT/ 12pm ET/ 6pm CET), entitled “See biology as it really happens – launch of a powerful magnetic force spectroscopy system to enable real-time study of the dynamics of individual molecular interactions at massive scale.” Depixus MAGNA One—the world’s first high-scale magnetic force spectroscopy platform—provides powerful new insights into how biomolecules interact. The technology opens the door to analyzing large numbers of individual interactions in parallel, revealing valuable details otherwise invisible to bulk measurement techniques. In this webinar, part of the MAGNA One commercial launch, Depixus’ CEO, Gordon Hamilton, will highlight this exciting new instrument system and its applications spanning fundamental research to drug discovery. In this webinar you’ll learn how their platform: 🧬Reveals biological variability in stunning detail by repeated analysis of thousands of individual interactions. 🔍 Gathers rich, detailed data from individual biomolecular interactions, revealing rare binding events often missed in bulk measurements. ⏱ Generates both kinetic & thermodynamic data. Don’t miss this chance to elevate your understanding of biomolecular interactions. Whether you’re involved in basic science, applied research, or drug development, the insights gained from Depixus MAGNA One could transform your work! Register here: https://lnkd.in/gzq-v2kx #RNATherapeutics #DrugDiscovery #Biotech #interactomics#Depixus

Finally published in Angewandte Chemie, our work on Taylor dispersion-induced phase separation (TDIPS). We present a novel application of the FIDA1 instrument by Fida Biosystems, which allows to screen conditions that modulate the liquid-liquid phase separation and condensation of a protein, using only a few tens of nanoliters per sample. The methods is very easy to use by anybody with access to the off-the-shelf FIDA1 instrument. I believe this method has the potential to be extremely useful for anybody interested in these phenomena in a biomedical or biotechnological context. And for the geeks (such as myself): there is some extremely rich non-equilibrium physical chemistry to be explored further. Check it out here: https://lnkd.in/d-At-y9e

Checkout the Fluorescent Dextran Derivatives by TdB Labs AB — available now at FroggaBio! Specialized fluorescent polysaccharides for studying permeability and transport in cells and tissues. 🧬🔬🔍 CONTACT US TO LEARN MORE: https://hubs.ly/Q02wlSlt0 TdB Labs' Fluorescent Dextran Derivatives are precise tools for investigating cellular and tissue permeability dynamics. With superior quality and reliability, these derivatives are crucial for drug delivery studies, microcirculation analysis, and molecular size indication. Their low polydispersity ensures consistent results, while a diverse range of fluorescent labels and molecular weights caters to varied experimental requirements. Illuminate your research with these advanced tools, enabling in-depth exploration of biological systems and enhancing our understanding of permeability phenomena. #FluorescentDextran #CellPermeability #TissueTransport #DrugDelivery #ResearchTools #Biology #Microscopy #FluorescenceImaging #ScientificResearch #FroggaBio #LabSupplies #Biotechnology #Innovation #Polysaccharides #CellularStudies #TdB_Labs #ScientificDiscovery #Biochemistry #PermeabilityAssays #MicrovascularFlow #Polydispersity #FluorescentLabels #MolecularBiology #ExperimentalTools #AdvancedResearch #LifeSciences #ScienceTools #LaboratoryInnovation #ExploreMore

At Enamine, we understand the critical role that high-quality chemical probes play in driving forward the frontiers of scientific research and drug discovery. That’s why we're thrilled to announce our newly developed library of chemical probes, designed to meet the diverse needs of researchers and scientists worldwide.   🔬 Why are chemical probes so essential? Chemical probes are invaluable tools in molecular biology, allowing researchers to study protein functions, dissect biological pathways, and validate new drug targets. Their precision and specificity make them indispensable for both basic research and the development of therapeutics.   📚 Highlighting Innovation A recent article in Nature (https://lnkd.in/dXk-XeDR) discusses the innovative approaches in chemical probe development and their transformative impact on biomedical research. Our new library is crafted with these cutting-edge insights in mind, ensuring that each probe meets the highest standards of efficacy and reliability.   👥 Join Us in Advancing Science We invite researchers, biologists, and chemists to explore our new chemical probe library and discover how our tools can accelerate your research projects. At Enamine Bioactive Compounds, we are committed to supporting your scientific endeavors with the best resources. More details: https://lnkd.in/duqk7BG4   #ChemicalProbes #DrugDiscovery #BiomedicalResearch #ScienceInnovation #EnamineBioactiveCompounds

✨ **Excited to Announce a New Publication!** ✨  Proud to share our latest research: **"Innovative Approach of High-Throughput Screening in the Drug Discovery Quest for Chronic Bronchitis Treatment"** 📄 In collaboration with an incredible team, this study explores the power of high-throughput screening (HTS) to identify potential therapeutic compounds for chronic bronchitis. HTS is proving to be an invaluable tool, enabling us to rapidly screen large libraries of compounds and efficiently pinpoint potential treatments. Our hope is that this approach will significantly advance the development of effective therapies for chronic bronchitis, a condition affecting millions worldwide. Thank you to my co-authors Dr. Muhammad Naveed, Khushbakht Javed, Ali Zafar, and everyone involved in making this research possible! For more details, read the full paper (https://lnkd.in/duDbPwPg). #research #drugdiscovery #chronicbronchitis #biotechnology #innovation #teamwork

Interdisciplinary approaches ensure that scientific advancements are effectively translated into clinical practice. By fostering collaboration between chemists, biomedical researchers, and clinicians, we can accelerate the development of new therapies and enhance health outcomes for patients worldwide. 👉 Discover more about our Invited Speaker, Prof. Michael Decker from the University of Würzburg Can you guess who the other speakers are at the Cannabinoid Translational Science Symposium? Check out the agenda here! 👉 https://lnkd.in/dKTdeyyB #cannabinoidtranslationalscience

Our discovery solutions: the drug discovery engine of choice, for even the most challenging targets! We know that in early drug discovery, every cog matters. If one cog is missing, you might not find any compounds, let alone the best hit ⚙️ Having the RIGHT protein in the beginning is crucial. We can help you identify the right protein, alongside the right discovery technologies, cutting-edge structural biology, tailor-made assay development, wide ranges of screening library access options, combined with the full spectrum of biophysical mode-of-action methodologies. Welcome to our Discovery Solutions, we’ve been expecting you! Let’s work together to find the best hit compounds, and make your drug discovery program a success! 🎯 https://lnkd.in/ev33Ufs6 #DrugDiscovery #EarlyDrugDiscovery #DrugDevelopment #DrugDesign #StructuralBiology #AssayDevelopment #ProteinScience

The Research Corporation for Science Advancement chose Professor Aaron Leconte as one of 11 researchers to receive a 2024 Cottrell Plus SEED Award! Leconte, an associate professor of chemistry, is studying chemically modified forms of DNA (known as "XNA”). Leconte’s project is titled “Towards XNA PCR: Evaluating the Potential of Fusion Domains to Improve XNA Polymerases.” Leconte is exploring how to better synthesize XNAs. This research can have far-reaching biotechnological applications from medical diagnostics to therapeutics. #ScienceResearch #Chemistry #Cottrell #XNA

Successful translational science relies on the seamless collaboration of three fundamental player types: 👩🔬 👨🔬 Medicinal/Computational Chemists: These innovators design and synthesize the molecules that serve as the foundation for new therapeutics. 🔬 🧬 Biochemists/Pharmacologists: Once synthesized, these experts validate the effectiveness of these molecules both in vitro and in vivo, ensuring their potential benefits. 🩺 💊 Clinicians/Regulators: Finally, these professionals are essential for regulating and prescribing these molecules as approved drugs, translating scientific breakthroughs into real-world applications. The First Cannabinoid Translational Science Symposium will be an incredible opportunity for these players to confront and brainstorm about these critical processes. We’re honored to have Prof. Nadine Jagerovic from the CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS  as one of our keynote speakers, bringing her valuable chemical expertise to the forefront 🌐 👉 Discover more about the program and other keynote speakers at https://lnkd.in/d3ZPBj-S   Let’s drive innovation together! 💡✨ 😎 #TranslationalScience #Keynote #Innovation #Cannabinoids #Collaboration #CannabinoidTranslationalScience

Did you hear? Earlier this week we launched Depixus MAGNA One! As part of our launch, we’re thrilled to announce an exclusive webinar in partnership with the Biophysical Society! 📅 Date: October 9, 2024 ⏰ Time: 12:00 PM - 1:00 PM EST 🎤 Hosted by: Gordon Hamilton, CEO of Depixus Depixus MAGNA One is the world’s first large-scale magnetic force spectroscopy platform. It allows you to see biology as it really happens—offering unprecedented real-time insights into thousands of biomolecular interactions simultaneously. Our game-changing laboratory instrument can analyze individual and multi-way interactions between DNA, RNA, proteins and small molecules, including challenging targets such as RNA and protein-protein interactions. Whether you're exploring fundamental biological mechanisms or developing novel therapeutics, don’t miss this chance to explore how Depixus MAGNA One can transform your research. 👉 Register for the webinar here: https://lnkd.in/gzq-v2kx 👈 #Biophysics #DrugDiscovery #Interactomics #DrugDevelopment #Webinar