Ab Studio’s Post

Excited to see Ab Studio’s first outlicensed Fc+ TCE asset, GB261 got a new deal by the licensee (Genorbio): https://lnkd.in/gis8nSSa Happy to see the first baby from our patent granted Fc+ TCE platform will move forward to autoimmune disease field. Since the world’s first Fc+ TCE, Catumaxomab, showed dose dependent hepatotoxicity in patients with EPCAM-positive cancers and one patient died from acute liver failure after receiving 10ug of catumaxomab, almost all major players in the TCE field either removed or silenced Fc effector function. GB261 is the world’s second Fc+ TCE entered into clinical trials and the world’s first Fc+ TCE showed great safety, efficacy balance in human at as high as 300mg dosage. The clinical POC data suggested that Ab Studio’s computer aided design platform could resolve challenges that traditional technologies can not. We hope our platforms, technologies and new assets to be outlicensed continue to support more partners!

Third Rock and Arie Belldegrun’s firm come together for CD20/CD3 bispecific out of China

Third Rock and Arie Belldegrun’s firm come together for CD20/CD3 bispecific out of China

endpts.com

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