Alicia Cowley, MD, MBA’s Post

Hey Arizona, We Can and Should do Better. While the rate of #colon #cancer and #rectalcancer cases in the United States has been falling for decades, the proportion of cases involving #young people has been on the rise. That national trend is being reflected in #Arizona statistics as well, with an uptick in the rate of #colorectal cancer cases in the state in individuals under 50 years old. The Arizona Cancer Registry reports that #colorectalcancer is the fourth most diagnosed cancer in the state and is Arizona’s second leading cause of cancer death. State officials have been raising concern about the upswing in colorectal cancer cases diagnosed in younger people for more than a decade. Nationally, the U.S. Preventive Services Task Force in 2021 lowered the recommended age to begin cancer-screening colonoscopies from 50 to 45 years old. Mounting evidence nationally led to a 2020 online “think tank” involving more than 400 scientists from academia, industry and government, along with patient advocates and others, to address concerns about the increasing prevalence of colon and rectal cancers in younger populations. “Both young people and doctors need to shed the notion that colorectal cancer is an ‘old person’s disease,’ several meeting participants stressed,” a National Cancer Institute article about the event said. “People should get used to looking at their stool and noticing changes, they noted.” In addition, getting more people screened for colorectal cancer is challenging. A 2023 American Cancer Society report showed that Arizona was tied for having the fifth-lowest #screening rate among adults ages 45 to 54 years old, with only a third receiving the recommended screenings. Arizonan, there are many ways to screen for colorectal cancers including, colonoscopy, stool testing and blood testing. Even better, we can prevent colorectal cancer by removing polyps, the precursors of cancer. For #Youngadults, know your #familyhistory as you might quality for earlier screening than the general population. see the full article at the link below. #cancerscreening #cancerprevention

#OvarianCancer is one of the leading causes of cancer deaths among women. Individuals with ovaries have a 1 in 87 lifetime risk of getting ovarian cancer, and then a 1 in 130 lifetime chance of dying from ovarian cancer. World Ovarian Cancer Day is an initiative set forth by the World Ovarian Cancer Coalition, which aims to highlight the importance of educating clinicians, researchers, and patients with the goal of closing the gaps that remain in health care systems to enable timely access to diagnostic tests and improve care for this patient population. Despite advancements in treating ovarian cancer, ongoing challenges persist, namely emphasizing the need for continued research and collaborative efforts that enhance early detection tools and treatment options. Ovarian cancer incidence is declining but we currently don't have the best diagnostic tools for early detection; however, we can prevent or reduce the risk via opportunistic salpingectomy (surgically removing the fallopian tubes). Also, we need more funding for clinical trials that allow us to evaluate better treatment options for all patients. Symptoms of ovarian cancer can be very non-specific. A few include, bloating; feeling full after eating a small amount; difficulty eating; back pain; pressure in your pelvis or abdomen; changes with urination; changes in bowel [movements]; and constipation. If you are persistently suffering from and of these symptoms, it is recommended that you consult with a gynecologist to determine if you should be referred to see a gynecologic oncologist. https://lnkd.in/eap7rY33 #cancerresearch

Breast and colon cancers are rising among younger people (under 50 years). The global incidence of early-onset cancer increased by 79.1% and early-onset cancer deaths rose by 27.7% from 1990 to 2019, a 2023 study in BMJ Oncology found. Data published last year in the Journal of the American Medical Association showed that from 2010 to 2019 in the United States, breast cancer accounted for the highest number of cases in this younger population, while rates of gastrointestinal cancers were rising the fastest. If you think that this is solely due to changes in diet and activity, think again. This article argues that the rise also includes healthy, active people who eat well. Something is happening to cause these cancers in young people. The article also points out that often a young person’s cancer is found at a much later stage. The USPSTF lowered the breast cancer screening guidelines to 40 years of age. However, younger women tend to have dense breasts. Mammograms, including 3-D tomosynthesis, are less effective in younger, dense breast tissue. Younger women need supplemental screening to find tumors in their dense tissue. This is an issue that not just affects us older generation, but our daughters. #breastcancerscreening #breastcancer

Breast and colon cancers are rising among younger people (under 50 years). The global incidence of early-onset cancer increased by 79.1% and early-onset cancer deaths rose by 27.7% from 1990 to 2019, a 2023 study in BMJ Oncology found. Data published last year in the Journal of the American Medical Association showed that from 2010 to 2019 in the United States, breast cancer accounted for the highest number of cases in this younger population, while rates of gastrointestinal cancers were rising the fastest. #oncology #oncologie #oncologist #oncologia #cancer #healthcare #drugdevelopment

🚨 Exciting Breakthrough in Cervical Cancer Screening! 🚨 I’m thrilled to share an incredible development in the fight against cervical cancer, highlighted by Dr. Mike Broadly. Cervical cancer, the fourth most common cancer in women worldwide, has long been a major health concern. Traditional screening methods like Pap smears can be uncomfortable and invasive, often deterring women from regular testing. 🌟 The Breakthrough: Researchers have developed a noninvasive urine test to detect HPV16 E7 oncoproteins, a key marker for cervical cancer. Published in the Microorganisms journal, this test could revolutionize how we approach cervical cancer screening. 📝 Study Highlights: • Involved women with various stages of cervical intraepithelial neoplasia (CIN), a precursor to cervical cancer. • Successfully detected E7 proteins in: • 80% of women with CIN1 • 71% with CIN2 • 38% with CIN3 • Particularly effective in early stages of HPV-related changes, vital for early intervention. 🌍 Why This Matters: This new urine test offers a much more accessible and less invasive alternative to current screening methods. By making screening easier, we can encourage more women to get tested regularly, which is crucial for early detection and treatment. 💰 Health and Financial Benefits: Early detection through this new test could significantly reduce the incidence of cervical cancer and related complications, such as heart disease and neurodegenerative diseases. Moreover, it can save on healthcare costs by preventing advanced cases. Professor Etsuro Ito from Waseda University, who led the research, highlighted the potential of this urine test in preventing cervical cancer, aligning with global health goals, especially in low- and middle-income countries. For detailed findings, you can read more about this breakthrough on Waseda University News. From my perspective, this new method holds great promise for making cervical cancer screening more accessible and practical, potentially saving countless lives through early detection and intervention. As we continue to advance in medical research, such innovations bring us closer to overcoming the challenges posed by chronic diseases. Let’s stay informed and proactive about our health! Thank you for reading, and I’d love to hear your feedback on this important health matter. https://lnkd.in/dNqZ-Tqh #HealthInnovation #CervicalCancer 

🚨 The latest study from the American Cancer Society paints a concerning picture of cancer trends in the United States. According to the report published in CA: A Cancer Journal for Clinicians, Americans are facing higher rates of various cancers, with diagnoses occurring at younger ages, marking a significant shift in the landscape of cancer incidence. Colorectal cancer, once a less common concern for individuals under 50, has now surged to the forefront, emerging as the leading cause of cancer deaths for men and the second leading cause for women in this age group. These findings underscore the pressing need for heightened awareness and proactive measures to address the evolving nature of cancer risk. While the report notes a decline in overall cancer deaths, experts caution that the rise in diagnoses of some of the most lethal forms of cancer could potentially lead to an increase in mortality rates. It's a stark reminder of the ongoing battle against this pervasive disease and the importance of continued research, early detection, and access to quality care. As we absorb this sobering data, let's reaffirm our commitment to advancing cancer prevention, treatment, and support for those impacted by this disease. Together, we can strive to make a meaningful difference in the fight against cancer. #CancerResearch #PublicHealth #CancerAwareness #Healthcare #AmericanCancerSociety https://lnkd.in/ec5JGDjP

🔬 Cervical Cancer: Understanding the Disease, Progress, and Treatment 🔬 As we continue to advance in medical research, it's crucial to shed light on prevalent health issues like cervical cancer. This disease affects millions worldwide, but with increased awareness and innovation, we're making significant strides in both understanding and treating it. Cervical cancer primarily develops from human papillomavirus (HPV) infection, highlighting the importance of HPV vaccination and regular screenings. Early detection through Pap smears or HPV tests can lead to timely interventions, potentially saving lives. In recent years, there have been remarkable advancements in cervical cancer treatment. From targeted therapies to immunotherapies, the arsenal against this disease is expanding. Additionally, precision medicine approaches are tailoring treatments based on individual genetic profiles, optimizing outcomes for patients. Furthermore, ongoing research is exploring novel therapeutic avenues, such as therapeutic vaccines and gene therapies, offering hope for improved outcomes and quality of life for patients. Let's continue to raise awareness, support research efforts, and empower individuals with knowledge about cervical cancer prevention and treatment. Together, we can make strides towards a future where cervical cancer is not just treatable, but preventable. #cervicalcancerawareness #medicaladvancements #healthcareinnovation https://lnkd.in/gz39D7H6

At Eve we know all too well the devastating impact that a diagnosis of ovarian cancer can have. Most often diagnosed at Stage three or four and with one in five people dying within three months of diagnosis. Today, research hit the headlines which shows two very exciting steps forward. That if women and people with ovaries with symptoms are referred quickly for investigation and treatment, that the complete surgical removal of cancer is possible even in more advanced disease, and that symptoms awareness in patients and doctors is key! This news shows the life-saving power of raising awareness of the signs, symptoms and risk factors of ovarian cancer. And that even for ovarian cancer, a disease with symptoms that are often described as ‘vague’, how effective it is to make people aware of recognising changes in their bodies and seeking medical help as soon as possible. What’s then vital, is that there is referral through the fast-track pathway and that women and people with symptoms of ovarian cancer are seen on time. Currently, waiting times to first treatment from referral for the gynae cancers is lagging behind others. Getting people referred and seen on time is essential. We have lots of information on the signs and symptoms of ovarian cancer on our website. Our Ask Eve nurses are also here to help with free and confidential information and advice on nurse@eveappeal.org.uk or 0808 802 0019. Read more about the news in The Guardian: https://lnkd.in/dhWXrwEm #CancerNews #OvarianCancer #EveAppeal #TheEveAppeal

**Pandemic Had Temporary Negative Effect on Breast Cancer Screening** The COVID-19 pandemic had a transient negative effect on breast cancer screening overall and a prolonged negative effect on follow-up screening, according to a study published in the May/June issue of the Annals of Family Medicine. **Key Findings:** 1. **Initial Screening Disruptions:** The pandemic caused a temporary decline in initial breast cancer screenings as healthcare resources were reallocated and lockdown measures were implemented. 📉 2. **Prolonged Impact on Follow-Up:** While initial screenings eventually resumed, the study found that follow-up screenings faced prolonged disruptions. This delay in follow-up care could have significant implications for early detection and treatment outcomes. ⏳ 3. **Healthcare System Strain:** The strain on the healthcare system during the pandemic contributed to these disruptions. Clinics and hospitals were overwhelmed, leading to rescheduling or cancellation of routine follow-ups. 🏥 4. **Implications for Patients:** The delayed follow-up screenings could result in later-stage diagnoses, which are typically more difficult to treat and have poorer prognoses. This highlights the need for healthcare systems to prioritize the resumption and continuity of cancer screening services even during public health crises. 👩⚕️ 5. **Future Preparedness:** The findings underscore the importance of developing robust healthcare strategies that ensure continuity of critical services like cancer screenings during pandemics or other emergencies. 🔄 In summary, while the immediate negative impact of the pandemic on breast cancer screening was temporary, the prolonged effect on follow-up screenings raises concerns about potential delays in cancer detection and treatment. This study emphasizes the need for healthcare systems to maintain essential services during crises to mitigate long-term health impacts. #BreastCancer #CancerScreening #Healthcare #COVID19

Reflections on Evolution of Breast Cancer Care in India Over the Past 4 Decades As per the latest trends, a higher proportion of the disease is being diagnosed among the younger age group in India (median age, 40–50) and the very young age group (median age, 20–35) as compared with the West (median age, > 60).[2]  The incidence in premenopausal women is increasing, especially in low- and middle-income countries.[3] In India, nearly 60% of breast cancer cases are diagnosed at stage III or IV of the disease,6 as compared to 30% in the United States.[7] https://lnkd.in/gbDx9FJN [2] India State-Level Disease Burden Initiative Cancer Collaborators: The burden of cancers and their variations across the states of India: The Global Burden of Disease Study 1990–2016. Lancet Oncol 19:1289-1306, 2018. [3] Heer E, Harper A, Escandor N, et al: Global burden and trends in premenopausal and postmenopausal breast cancer. Lancet Glob Health 8:e1027-e1037, 2020 [7] American Cancer Society: Breast Cancer Facts & Figures 2019-2020. Atlanta, American Cancer Society, 2019. Dr.Kavita Yadav By Rakesh Chopra, MD; Dr.Kavita Yadav Kavita Yadav, BDS, MPH; Vivek Agarwala, MD, DM, DNB; and Ravi Mehrotra, MD, DPhil, FRCPath #breastcancer #india #incidence