Managing Director at MD Bioproducts - Inflammation - Neurology - Immunology - A Life Science Research Products Company (A MD Biosciences Group Company). Co-Founder.
A new study has found an interesting link between gene mutations in blood #cancer and #arthritis. The publication explains how specific gene mutations in blood cancer can impact autoimmune diseases such as seronegative RA. The study suggests that effective metabolic therapies in treating blood cancer may help arthritis patients. → Conclusion: • IDH mutant myeloid neoplasms are associated with seronegative rheumatoid arthritis. • High levels of 2-hydroxyglutarate mediate IDH-associated activation of innate immune response. → Lih En Hong, Mihir D Wechalekar, and Devendra Hiwase led the research team at the Royal Adelaide Hospital in Australia for this study. → Publication: Hong, Lih En, et al. "IDH Mutant Myeloid Neoplasms are Associated with Seronegative Rheumatoid Arthritis and Innate Immune Activation." Blood (2024). 📖 Read on…https://lnkd.in/egV5am-P #Inflammation #Immunotherapy #DrugDevelopment
