Alloy Therapeutics, Inc.’s Post

Follow along as BioSpace keeps you up-to-date on the latest pharma and biotech layoffs. Today's Biopharma Layoff Tracker 2024 updates include Lykos Therapeutics, Galera Therapeutics, Inc., GRAIL and more. https://hubs.li/Q02LJCPF0 #layoffs #pharma #biotech #biospace

Thoughts on this? >> BioMarin sheds 170 jobs in wake of narrowed R&D refocus - Fierce Biotech >> Comment below! >>> lqventures.com #strategy #competitiveintelligence #marketing #biotech #healthcare #pharmaceutical #pharma #competitivemarketing

Thoughts on this? >> BioMarin sheds 170 jobs in wake of narrowed R&D refocus - Fierce Biotech >> Comment below! >>> lqventures.com #strategy #competitiveintelligence #marketing #biotech #competitivemarketing #pharma #healthcare #pharmaceutical

The monitoring of cell cultures is crucial for gaining a deeper understanding of the process and ensuring the production of safe and high-quality therapeutics. Introducing One-batch calibration,the innovative approach greatly simplifies the Raman calibration phase while providing comparable levels of accuracy for real-time monitoring compared to standard modeling methods involvingmultiple calibration batches. To know more, please follow the application note

Thoughts on this? >> BioMarin confirms layoffs and R&D cuts - LabPulse >> Comment below! >>> lqventures.com #strategy #competitiveintelligence #marketing #pharma #biotech #healthcare #pharmaceutical #competitivemarketing

Thoughts on this? >> BioMarin confirms layoffs and R&D cuts - LabPulse >> Comment below! >>> lqventures.com #strategy #competitiveintelligence #marketing #competitivemarketing #biotech #healthcare #pharma #pharmaceutical

A major challenge has emerged from the increasingly rapid timelines required for achieving IND-ready processes for clinical development. There is a bottleneck in the provision of toxicology data to support INDs for new therapeutics and the delivery of FIH studies. By turning to earlier Tox material generation, you gain more time to complete toxicology studies without impacting the IND submission experience. Dig deeper into the science in this article from Drug Target Review authored by my colleagues Alejandro Fernandez Martell, Global Principal Scientist, and James Berrie, Technical Director, Global Process Development. https://lnkd.in/dC9qCqEu

https://lnkd.in/eV6v2PGU Preclinical Toxicology vs Clinical: Key Considerations in Using Lipid-Based Formulations: Anette Müllertz, PhD, Grace Furman, PhD, and Lisa Caralli say developers should first understand the developability challenges for their molecule, then a toolkit of enabling technologies can be identified to overcome those factors and individually leveraged to create fit for purpose formulations for use in preclinical and clinical studies.

In the in vitro screening stage of small nucleic acid drugs, there are dozens to hundreds of candidate sequences, and different drug treatment concentrations and biological replicates need to be considered. This means that a lot of time is needed to pre-treat the samples before starting RT-qPCR screening. Therefore, it is necessary to establish a high-throughput and efficient small nucleic acid sequence screening program：High Throghuput Screening Solution For Candidate Molecules of Small Nucleic Acid Drugs！

Invitae (a cancer testing lab) was once worth $7B and is likely be purchased out of bankruptcy for $239M. That's 3% of peak value! Invitae cites poorly-timed acquisitions, macroeconomic headwinds and EMPLOYEE TURNOVER as the main reasons... Do those issues ring a bell for anyone in cannabis? Turnover is a metastatic disease for ANY laboratory. Once that malignancy has a foothold in the lab (it only takes 1-2 key employees) it's hard to cure without long-term, toxic side effects. This is where E4 Bioscience comes in. They provide technical recruiting to labs and use VALIDATED technology and HR science to identify high-value employees that STAY. And, unlike most labs, they provide 100% transparency by sharing all validation data with anyone who asks nicely for a good reason. https://lnkd.in/gfTFbdQa #recruiting #cannabis #cannabisbusiness #laboratory