AM Technology’s Post

🔬 Have you heard about the batch reactor? It’s a fundamental tool in chemical manufacturing, especially for high-value products like pharmaceuticals. Batch reactors offer precise control over temperature, pressure, and reaction time, making them indispensable for industries that require flexibility and accuracy. Curious about how this reactor transforms raw chemicals into finished products in one go? Watch our latest video and explore more chemical engineering insights! 👨🔬 #BatchReactor #ChemicalEngineering #ProcessControl #PharmaceuticalEngineering #EngineeringInnovation #batchreactor #chemicalengineering #processcontrol #pharmaceuticalengineering #industrialchemistry #reactiontime #engineeringexplained #processengineering #chemicalprocess #scienceandengineering #engineeringprofessionals #chemicalindustry #engineeringinnovation #reactioncontrol #chemicalplant

Batch Reactor A batch reactor is a type of reactor used in chemical processing and other industrial applications. It is a closed system where the reactants are loaded, the reaction takes place, and the products are then removed. Some characteristics of a batch reactor: 1. Discrete Batches: Reactants are loaded into the reactor, the reaction occurs, and then the products are removed. This is done in discrete batches rather than continuously. 2. No Inflow/Outflow: There is no continuous flow of reactants in or products out during the reaction. The contents of the reactor remain static during the process. 3. Mixing and Heating: Batch reactors typically include mechanisms for mixing the contents and controlling the temperature to optimize the reaction. 4. Batch-wise Operation: The entire process of loading, reacting, and unloading happens in a discrete batch rather than continuously. Batch reactors are commonly used for reactions that require precise control, complex multi-step processes, or batch-wise production. Some examples include pharmaceutical manufacturing, specialty chemical production, and pilot-scale research and development. The batch-wise nature provides flexibility, but can be less efficient than continuous flow reactors for high-volume production. #reactors #reactions #valves #chemical #oilandgasindustry #petrochemical

What does process development mean in continuous-flow manufacturing? Well, specifically for the life sciences and pharmaceutical industry, our Coflore flow reactor range puts process development at the core of reaction design. Optimising the efficiency, safety, and productivity of reactions at any scale is made simple at AM Technology, with our development services leading various life science businesses to better, more consistent products and faster innovations. The development work that goes into producing a continuous chemical process aims to achieve high-quality product and yield, whilst maximising raw materials, reducing waste, improving energy efficiency and optimising reaction speed. With flow, the scale of a reaction is irrelevant. 📈📈📈 Once a process has been developed, we aim to ensure that you can take advantage of all the benefits no matter the reaction volume > https://lnkd.in/eaSdNkRM #processdevelopment #lifesciences #drugproduction

***Continuous Manufacturing with Centrifugal Partition Chromatography!*** Key Advantages: - Significantly increase the productivity of downstream chemical production. - Purify even unstable compounds with an expanded purification parameter window and a wide variety of solvents. - Separate overlapping peaks cyclically for high purity. - Minimize both CAPEX and OPEX. No need for restarting separations, silica gel, cartridges, or high solvent consumption, thanks to effective recycling. - The absence of batch-related constraints allows a smoother transition to higher production volumes without disrupting the overall process, making scale-up efforts easier. - Continuous manufacturing enables a seamless production flow, ensuring a steady output, maximizing productivity, and minimizing downtime. Predictive maintenance techniques can prevent equipment downtime and optimize equipment lifespan. - Continuous manufacturing requires significantly less space in your facility compared to other complicated instruments. - If a larger sample capacity is important, CPC offers higher productivity, resolution, and purity than MCSGP - Separate multiple components from a complex crude while using any grade purity of solvent instead of HPLC columns of SMB - Apply it for chiral separation, nucleotide purification, protein isolation, downstream purification process in flow chemistry Embrace innovation with Continuous CPC! Find more here: https://lnkd.in/dWdiKU9c #chromatography #laboratory #pharma #downstreamprocessing #purification #continuousmanufacturing #liquidchromatography #continuousbioprocessing #bioprocessing #pharmaceutical #pharmaceuticalindustry #manufacturing #downstreamprocessing #GMP #biopharma #biotech #biotechnology #cannabisresearch #medicalcannabis #SMB #MCSGP #flowchemistry #chiralseparation

Our course tutor Aaron Sarafinas is a recognized expert in process development and mixing technology in the chemical and pharmaceutical industries. He formed Sarafinas Process & Mixing Consulting LLC to help chemists achieve faster process development, scaling, and troubleshooting while leveraging advantaged mixing technology. Aaron will start off the 'Applied Mixing' course (held online on 8-11 April) looking into some essential basics of mixing technology. With those fundamentals, he will then progress through different mixing applications in increasing levels of complexity: single-phase (blending and heat transfer), multiple phase (solid-liquid, immiscible liquid, gas-liquid, and 3-phase), and mixing in competitive rate processes (reactions and crystallizations). Throughout, he will look at scale-up and scale-down by using examples from industrial processes which have a variety of mixing requirements.  A previous course attendee told us ‘The course was really great, the topics talked about were from really basic terms using simple case studies that were really helpful to understand. Also, if we had any questions that were not included in the handbook, Dr Aaron prepared an addendum and gave the answer in the next session, It’s really helpful. Thank You.’ Please visit our website for more information and to register at https://lnkd.in/eXUePsuk #mixingtechnology #processchemistry #organicchemistry #pharmaceuticalindustry #scaleup

Continuous Manufacturing with Centrifugal Partition Chromatography! Revolutionize your #purification processes with Continuous CPC! Key Features: High productivity: Significantly increase the productivity of downstream chemical production. Pure compounds with specific needs: Purify even unstable compounds with an expanded purification parameter window and a wide variety of solvents. High purity, optimized results: Separate overlapping peaks cyclically for high purity. Cost-Effective: Continuous CPC minimizes both CAPEX and OPEX. No need for restarting separations, silica gel, cartridges, or high solvent consumption, thanks to effective recycling. Improved Ability to Scale Up: The absence of batch-related constraints allows a smoother transition to higher production volumes without disrupting the overall process, making scale-up efforts easier. Fast and Continuous Operation: Continuous manufacturing enables a seamless production flow, ensuring a steady output, maximizing productivity, and minimizing downtime. Predictive maintenance techniques can prevent equipment downtime and optimize equipment lifespan. Decreased footprint: Continuous manufacturing requires significantly less space in your facility compared to other complicated instruments. Continuous CPC vs MCSGP: If larger sample capacity is important, CPC offers high productivity, resolution, and purity Continuous CPC vs SMB: Separate multiple components from a complex crude while using any grade purity of solvent instead of HPLC columns Application fields: chiral separation, nucleotide purification, protein isolation, downstream purification process in flow chemistry Embrace innovation with Continuous CPC – the future of #chromatography is here! Find more here: https://lnkd.in/dWdiKU9c #chromatography #laboratory #pharma #downstreamprocessing #purification #continuousmanufacturing #liquidchromatography #continuousbioprocessing #bioprocessing #pharmaceutical #pharmaceuticalindustry #manufacturing #downstreamprocessing #GMP #biopharma #biotech #biotechnology #cannabisresearch #medicalcannabis #SMB #MCSGP #flowchemistry #chiralseparation

50% of all chemical, pharmaceutical and food products are bulk materials. But what makes particle collectives so special and why is it more difficult to model solids processes? While a bulk material from particles at a statice state can transfer compressive and tensile stresses and behaves more like a solid, in a moving or "fluidized" state it exhibits liquid-like properties. Heavy objects sink in a fluidized particle bed and light ones float on top. If you are working with bulk materials, what are the hurdles you face in your processes? #mysteriesofbulksolids #processsimulation #digitalization #solidsprocesses

[Smart process] At SEQENS, we empower innovation to bring the best solutions to our customers, with a constant concern for sustainability. 🌍 In the manufacturing of Active Pharmaceutical Ingredients (APIs), significant effort is being deployed to reduce resource usage by driving process intensification. Best practices and technologies that have a positive impact contribution should be considered. Typically, solvents and water are the largest contributions to mass intensity. 💧   For illustration, flow chemistry provides the opportunity for decreased solvent usage through the increased implementation of more atom-efficient reactions. ♻️   The process intensification afforded by flow chemistry can enable significant improvements in yield, product quality, and efficiency. It may also facilitate the expansion of the Green Chemistry “toolbox” of favorable chemical reactions.   📖 For more information, visit our knowledge center and download our white paper about the 𝗗𝗲𝘀𝗶𝗴𝗻 𝗼𝗳 𝗔𝗱𝘃𝗮𝗻𝗰𝗲𝗱 𝗧𝗼𝗼𝗹𝘀 𝗳𝗼𝗿 𝗦𝗺𝗮𝗿𝘁 𝗣𝗿𝗼𝗰𝗲𝘀𝘀 ➡️ https://lnkd.in/d9jJRtar   #ourscienceforyourfuture #flowchemistry #processintensification #whitepaper #chemicalprocess #greenchemistry #chemicalengineering #smallmolecules

Our latest webinar is now available on demand! Critical strength: perfecting catalyst and pellet crush testing. Catalysts must be strong to keep operations smooth and avoid costly disruptions. This webinar covers essential testing for single pellets and bulk catalysts to ensure they meet rigorous strength requirements. What You’ll Learn in the Webinar and Live Demo: • Overview of pellet and catalyst testing • Industries where testing is required • Selecting ideal testers and test fixtures • Factors that affect repeatability and consistency Who should watch? Manufacturing, production, and quality managers and engineers involved in: • Plastics and packaging • Petroleum, oil, and gas • Medical and pharmaceutical container manufacturing Watch now: https://hubs.la/Q02WMfVT0 #ondemandwebinar #CatalystTesting #QualityControl #MechanicalTesting

📣 Ensuring Purity with Precision: Discover the Power of Liquid Particle Count Testing with BIOCHEM! Liquid Particle Count (LPC) testing is a method used to measure and analyze the number and size of particulate contaminants in a liquid sample. This type of testing is critical in various industries, including pharmaceuticals, biotechnology, and electrical & electronics, where the purity of liquids is essential for product quality, safety, and performance. The purpose of LPC testing is to ensure:- 1.) The products meet specified cleanliness and purity standards 2.) Monitor the manufacturing processes to detect contamination and prevent defects 3.) Used in developing new products to ensure that formulations meet required purity levels Many companies are required to test for LPC in order to comply with regulatory requirements set by agencies such as the FDA, EMA, or ISO standards. 💦 BIOCHEM has the capability to support you in ensuring the purity and quality of products to meet stringent quality and safety standards, thereby protecting consumers and maintaining compliance with regulatory requirements. 📢 WhatsApp us now for free consultation at: www.wasap.my/60124259368, or email your inquiries to: info@biochem.com.my Read More: https://lnkd.in/gZShfuwZ 👉🏼Follow our Website: www.biochem.com.my 👉🏼Follow our Facebook: https://lnkd.in/g2Jxr7aQ 👉🏼Follow our Instagram: https://lnkd.in/g8u8mdsH #LiquidParticleCountTesting #LPCtest #QualityControl #ContaminationControl #Biochem #LabAnalysis #IndustrialQuality #ProductSafety