Dr. Amine ZORGANI’s Post

Sample collection, transport and handling are important factors in the design of nutritional surveys. Here we show the effect of changes to the sampling protocol on individual nutritional biomarkers.

What Is The Difference Between Prebiotics, Probiotics, And Postbiotics? #Mythoughts I am happy to share my latest thoughts on the importance of understanding and clearly communicating the differences between prebiotics, probiotics, and postbiotics, in collaboration with the Biocodex Microbiota Institute. These terms are often used interchangeably, which can cause confusion, especially for those outside the scientific community. Accurately explaining their distinct roles is crucial because each contributes differently to health. Educating the public on these concepts empowers people to make informed decisions about their diet and supplements, ultimately improving gut health and overall well-being. HAPPY to hear your THOUGHTS and stay POSITIVE! #Myinspiration Link to the article here: “Discipline is the bridge between goals and accomplishment” Jim Rohn https://lnkd.in/ek6zpvyN #microbiome #science #biology #health #pharma #diet #nutrition #probiotics #therapeutics #startup #biotech

Through technology and rigorous, world-class science, we are committed to uncovering the mysteries of the #microbiome and translating this knowledge into actionable insights for our customers. #microbiota  #microbiomeanalysis #microbiomeresearch #microbiomesequencing #nutrition #bioinformatics #clinicalresearch #Metagenomics #Metabolomics #clinicaltrials

Why choose a Methylated Supplement over Traditional Supplements? 🤓🔥💪 Understanding Methylation is Key to Optimal Wellness! ❤️ Methylation is a vital chemical process in the body that influences gene expression and numerous bodily functions. From energy metabolism to DNA repair, proper methylation is crucial for maintaining overall health. Why does it matter? When methylation isn't functioning optimally, it can lead to various symptoms and health issues, including fatigue, mood swings, and digestive problems.😭😴 As a 🔟❌ Health Ambassador I’m excited to share this knowledge so YOU can empower empower yourself and take control of your own health journey. DM me ➡️ It’s time to explore the role of methylation in your wellness and consider genetic testing to uncover potential gene mutations and nutrient deficiencies so you can prioritize your health with knowledge and understanding! 💡 ✨https://lnkd.in/eXyVr5RF As a Certified 🔟❌ Coach, certified Personal Trainer & Nutrition Coach, 🔟❌ Health Ambassador, Trainer and Speaker I ❤️ being able to bring amazing opportunities for growth, success, and healthy living to you! #AbsoluteLiving365 💎 #10X #empire #lifestyle #goalsetting #success #goals #entrepreneur #75hard #coach #FitnessJourney #absoluteliving365 #WellnessJourney #MethylatedVitamins #personaltrainer #SuperhumanProtocol #WellnessJourney #MethylationMatters #OptimalWellness #GeneticTesting #personalexcellence #nutritioncoach #vitamins #supplements #healthylifestyle

4-HYDROXYINDOLE: A GUT MICROBIOTA-DERIVED METABOLITE AGAINST ENDOMETRIOSIS Endometriosis is a chronic inflammatory disorder that afflicts up to 198 million women worldwide and is characterized by the growth of endometrium outside the uterus in the form of inflamed lesions that cause severe pain. The gynecological pathology is a major health concern that substantially affects the quality of life of women, and, in serious cases, renders them infertile. Its diagnosis is achieved through invasive procedures such as exploratory laparoscopy, while surgical removal of lesions for its treatment has an immediate effect on post-treatment conceptions. Although the disease is not neoplastic, the symptoms recur in up to 75% of cases. Therefore, the need to rethink the diagnosis and management of endometriosis is acknowledged. Scientists from Baylor College of Medicine combined the gut metabolomic and microbiota signatures in the stool samples from women with endometriosis to identify a gut-bacteria-derived therapeutic intervention candidate, 4-hydroxyindole. They demonstrate that 4-hydroxyindole prevents the formation of endometriotic lesions, augments their regression, and reduces disease-associated pain. A unique bacteria-derived metabolite signature intricately linked to endometriosis. An altered fecal metabolite profile exhibits also a strong correlation with that observed in inflammatory bowel disease (IBD), revealing intriguing connections between these two conditions. In particular, scientists observed that 4-hydroxyindole is lower in endometriosis stool samples. Extensive in vivo studies found that 4-hydroxyindole suppressed the initiation and progression of endometriosis-associated inflammation and hyperalgesia in heterologous mouse and in pre-clinical models of the disease. Besides, they also identified altered bacteria-derived distinct metabolites that could potentially be used for non-invasive diagnosis of the disease. #endometriosis #4Hydroxyindole #GutMetabolites #IBD https://lnkd.in/dbPQ44YN

We're beginning to connect the dots between #endometriosis and #gut #health. While this study was small, it brings to light a potential research path for a new diagnostic marker, and maybe even a new therapy. #womens #health #microbiome

A Microbiome-Derived Metabolite Shows Efficacy in Reducing the progression of Endometriosis #Mysummary The study included 18 women with endometriosis (ranging from stage I to IV) and 31 healthy controls. Its aim was to identify metabolites linked to the onset and progression of endometriosis. Key results: 🔹Key Metabolite – 4-Hydroxyindole (4HI): The levels of the gut-derived metabolite 4-hydroxyindole (4HI) were significantly lower in the stool samples of women with endometriosis. 🔹Therapeutic Potential of 4HI: The bacteria-derived metabolite 4HI shows promise in reducing inflammation, lesion mass, and pain in endometriosis, making it a candidate for future therapies. 🔹Link to Inflammatory Bowel Disease (IBD): The metabolite signature observed in endometriosis shares several similarities with inflammatory bowel disease (IBD), hinting at a possible connection between these two conditions. 🔹Potential for Non-Invasive Diagnostics: These findings suggest that certain metabolites could be non-invasive diagnostic biomarkers for endometriosis. #Mythoughts 4HI is a gut microbiota-derived metabolite produced from the bacterial metabolism of tryptophan. Key bacteria involved in its production include Faecalibacterium and Lachnospiraceae, which are generally associated with a healthy gut microbiome. A decrease in these beneficial bacteria may lead to lower levels of 4HI, which could play a role in the pathogenesis of conditions like endometriosis. Tryptophan is the precursor to indole derivatives like 4HI. Including tryptophan-rich foods like eggs, turkey, salmon, dairy, seeds, and nuts can help ensure the availability of this amino acid for bacterial metabolism. HAPPY to hear your THOUGHTS and stay POSITIVE! #Myinspiration “Just when you think it can't get any worse, it can. And just when you think it can't get any better, it can.” Nicholas Spark Link to the paper here: https://lnkd.in/e8jhjY8m #microbiome #science #biology #health #pharma #diet #nutrition #probiotics #therapeutics #startup #biotech

Clever detective work by Dr. Amine Zorgani that shows additional benefits from what we already know about the value of following a healthy diet including rich foods like eggs, turkey, salmon, dairy, seeds, and nuts. And thanks to Dr. Borges for sharing the post.

Will You Build Your Brand on the Legacy of Yesterday or the Foundation of the Future? Liposomal and micronization technologies have been game-changers in the nutraceutical space, offering enhanced delivery solutions and setting higher standards. These innovations have paved the path for better health outcomes and have been instrumental in shaping the industry. But in a world where health and wellness are evolving rapidly, relying on yesterday’s solutions is no longer an option. As we continue to push the boundaries of what’s achievable, we recognize that every technology has its limits. Liposomal and micronization delivery, despite their strengths, will always be bound by certain fundamental constraints, no matter how many times they are re-engineered. That’s where BioSNEDS™ steps up. By respecting the legacy of the past and addressing its limitations, BioSNEDS™ is revolutionizing nutraceutical delivery with a bioavailability boost of up to 18,000%. It's not just a solution for today but an adaptable technology designed to meet the challenges of the future. With targeted delivery to cells, the blood-brain barrier, and soon, the mitochondria, BioSNEDS™ offers precision and efficiency like never seen before. It’s not just about replacing the old; it’s about building a brighter future by evolving to meet the ever-growing needs of our industry and those we serve. The future of your brand lies in the decisions you make today. #Supplements #Bioavailability #Nutraceuticals #VerdantNatureINC #BioSNEDS #HealthandWellness #Liposomal #FunctionalFood #Nutrition #DietarySupplements

Have you ever wanted to be part of a global community, full of like-minded individuals…within a projected multi-billion dollar company offering the ability to be a FOUNDER and earn shares of a 2% Global Revenue Share Pool for the lifetime of the company? Got questions? I’ve got answers! #Health #Wellness #Business #Nutrition #Phytonutrients #Vitamins #Cellular #Absorption #Delivery #Technology #Bioavailability #Epigenetics #Physicians #PhysiciansDeskReference #PDR