Lachance Aquaculture Farming’s Post

🔊 《Effects of bile acids on the growth performance, lipid metabolism, non-specific immunity and intestinal microbiota of Pacific white shrimp (Litopenaeus vannamei)》 🦐 Shrimp (1.09 ± 0.04 g) were assigned randomly to 15 tanks (400 L, three tanks in each group, 60 shrimp in each tank) for 60 days.  1️⃣ Dietary supplementation of 0.2–0.3 g/kg bile acids could promote the growth performance. 2️⃣ Lipid metabolism and antioxidant capacity in shrimp, and enhance the immune response of shrimp mainly through NF-κB-mediated signalling pathway. 3️⃣ High- throughput sequencing analysis showed that bile acids exerted beneficial effects on the structure and function of intestinal microbiota, and the biotransformation process of bile acids completed by the microbiota was also found in the intestines of shrimp. Dietary supplementation with 0.5 g/kg bile acids had side effects on shrimp. 🦉 Considering the feed cost, we recommend the shrimp diet supplemented with bile acids at the 0.2 g/kg level. DOI：org/10.1111/anu.13338

This recently published study investigated the effects of supplementing laying hen diets with rosemary leaf powder (0.3%). It was found that feeding the rosemary powder enhanced the Haugh unit (a measure of egg white quality) and reduced the yolk n-6/n-3 polyunsaturated fatty acid (PUFA) ratio. From an #antioxidant capacity perspective, serum levels of superoxide dismutase (SOD), were increased with rosemary powder supplementation. Feeding rosemary powder upregulated the expression of jejunal zonula occludens-1 (ZO-1), a tight junction protein involved in maintaining gut barrier integrity. Supplementing the diet with rosemary powder was also found to alter the composition of cecal microbiota, increasing the relative abundance of beneficial bacteria such as  Rikenellaceae, Turicibacter, and butyrate-producing microbes. It would be interesting to follow up with studies evaluating the dose response to rosemary powder, and it would also be interesting to see how rosemary powder might interact with diets enriched in n-3 fatty acids. #botanical #egg #animalnutrition https://lnkd.in/gdSxGMNy

Homocysteine is an amino acid present in the body in tiny amounts. It is produced during the metabolism of methionine, an essential amino acid obtained from the diet, primarily through consuming meat, eggs, milk, and legumes. Under normal physiological conditions, homocysteine is converted into other compounds with the help of vitamins B6, B12, and folic acid. Homocysteine is considered high when it exceeds 16 µmol/L. Hyperhomocysteinemia can distinguish 3 risk classes, depending on the levels of homocysteine in the blood: • 16-30 μmol/L: moderate risk • 31-100 μmol/L: medium risk • >100 μmol/L: severe risk Hyperhomocysteinemia occurs due to the interaction of several factors: • Genetic factors (inherited or acquired diseases) • Environmental factors (such as a diet low in vegetables) • Use of certain medications An elevated homocysteine value may be linked to some diseases, including: • Pregnancy complications • Certain forms of cancer • Coronary artery disease • Atherosclerosis and peripheral vessel thrombosis • Deficits in cognitive function (especially in older people) It is important to monitor the level of homocysteine as it is implicated in numerous disease processes, including endothelial damage (it may, in fact, damage vessel walls, causing structural and functional problems), which is of considerable clinical importance. Excess homocysteine in the blood, or hyperhomocysteinemia, does not result in any clinical symptoms or signs. Therefore, a blood test is the only way to detect increased homocysteine levels. A blood test from a vein should be taken on an empty stomach after 10-12 hours of fasting. Before the blood draws, it is necessary to rest and refrain from smoking for at least 15 minutes. If hyperhomocysteinemia is not caused by genetic or other diseases but by insufficient intake of folic acid and vitamins B6 and B12, supplementing these elements by correcting the diet is necessary. In particular, the diet to combat hyperhomocysteinemia should be rich in raw fruit and vegetables. Vegetables must be fresh because the folates and vitamins they contain deteriorate quickly and with cooking. #hospitals #innovation #doh #research #homocysteine

Modern sows face increased nutritional challenges due to rapid genetic improvements in reproductive performance. These enhancements have led to larger litter sizes and heavier piglets, increasing the nutrient demands on sows during gestation and lactation. Effective nutritional management strategies are crucial to address the increased demands and ensure the well-being and performance of both sows and piglets. This review highlights the importance of updating feeding programs and utilizing bioactive compounds to support modern sows' nutritional needs. Current issues: - Since 2012, litter size at birth has increased by 2.26 pigs, and foetal weight has increased by 0.22 kg per piglet. - Modern sows require 31% more lysine during gestation compared to current feeding programs. - Current feeding programs are insufficient, leading to excessive maternal tissue loss and reproductive failure. - Nutritional deficiencies can lead to lameness, affecting sow longevity and productivity. - High oxidative stress can negatively impact colostrum and milk quality. - There is also an increased risk of pelvic organ prolapse due to larger litters and higher metabolic demands. Potential Solutions: - Feeding programs need to be revised to support the enhanced reproductive capabilities of modern sows. - Incorporating bioactive compounds in feed can help mitigate physiological challenges and improve overall sow and piglet performance. - Different bioactive compounds have been investigated for their potential to reduce disease, improve colostrum and milk quality, and support intestinal health. - Examples include selenium sources, catechins, plant extracts, calcium chloride, phytase, algae, yeast derivatives, fibre sources, and probiotics. Source: https://lnkd.in/eUkS7jB3 #sows #nutrition #performance #feedingprograms

Cholesterol (CHO) is an expensive essential nutrient for shrimp and bile acids (BA) are emulsifiers responsible for lipid absorption in vertebrates.  This study was carried out to investigate the interactive effects of dietary CHO and BA on the growth performance, lipid metabolism, immune response and intestinal microbiota of Litopenaeus vannamei and explore the sparing effect of BA on CHO in shrimp diets.... #cholesterol #BA #vannamei #shrimp_diet

SCI Sharing of BA in commom carp (Cyprinus carpio L.) This study was conducted to investigate the tolerance dose of bile acids as a feed additive in high plant protein (PP) diets of common carp, by evaluating the responses in growth performance, hepatopancreas and intestinal histology, and glucose and lipid metabolism regulation.  👉 Safety margin of dietary bile acids of common carp in a high plant protein diet is 600 mg/kg, 10-fold of recommended level. 👉 Dietary bile acids supplementation can enhance growth performance, and decrease hepatopancreas lipid content. 👉 Dietary bile acids supplementation plays important roles to mitigate intestinal lesions and fatty liver induced by high plant protein diet. 👉 Dietary bile acids supplementation can alleviate metabolic disorders through regulation of glucose and lipid metabolism. 👉 Dietary bile acids inclusion can improve cell proliferation and self-repair by activation of phosphorylated ERK1/2 pathways. #SCI #BA #common_carp #plant_protein #intestinal #fatty_liver

Cobalamin (Vitamin B12) & Folate: Essential Nutrients for Optimal Health 🌟 #HealthNutrition   Cobalamin (Vitamin B12) and folate are vital for our biochemistry, especially in methylation processes crucial for DNA synthesis/repair & amino acid metabolism. Their synergy is key for effective methylation, emphasizing the need for a diet rich in both nutrients. 🥬🥩   Cobalamin, found mainly in animal products, acts as a cofactor for methionine synthase, essential for converting homocysteine to methionine, a process also needing folate. Folate, abundant in leafy veggies, is vital for creating THF, necessary for methionine synthesis from homocysteine, impacting protein synthesis and DNA methylation. 🧬   Both nutrients are crucial for maintaining low homocysteine levels, linked to health risks when elevated, and preventing megaloblastic anemia, characterized by large, immature red blood cells due to impaired DNA synthesis. 🩸   Studies highlight the importance of a balanced intake of cobalamin and folate, showing that cobalamin deficiency impairs folate function, affecting the transfer of single-carbon units essential for our body's biochemistry, even causing issues in the absence of methylTHF trapping. Methionine's metabolism provides formate, and both formylTHF and methionine can counteract cobalamin deficiency effects, illustrating their interlinked roles. 🔄   For optimal health and methylation, incorporating both animal products (for cobalamin) and leafy vegetables (for folate) into our diet is essential. Understanding their partnership helps in formulating dietary strategies to improve methylation processes and avoid deficiencies. 🍽️   Let's embrace the importance of cobalamin and folate for our well-being! 💪 #VitaminB12 #Folate #DNARepair #Methylation #NutritionTips #HealthyEating

📢 Exciting News! I’m thrilled to announce the publication of my latest research article in the Turkish Journal of Science & Technology! 🎉 The study explores the effect of dietary zinc on antioxidant parameters in juvenile common carp (Cyprinus carpio), focusing on how zinc influences the fish's muscle and liver tissues. This research adds valuable insights into improving fish nutrition and health through dietary supplementation. You can check out the full article here: https://lnkd.in/dWW-95cJ #Research #Aquaculture #Antioxidants #FishHealth #ZincSupplementation #Biology #FishScience #AcademicPublication