Atlas of Variant Effects Alliance reposted this
Director of Program Operations for the Center for the Multiplex Assessment of Phenotype (CMAP), the Center for Actionable Variant Analysis (CAVA) and the Atlas of Variant Effects Alliance.
Incredible! Also, Dr Iris Cohn (& colleague Dr Michelle Axford) (The Hospital for Sick Children) were recently interviewed about their work on the Atlas of Variant Effects Alliance sponsored Variants and Us Podcast. You can learn more about this team and pharmacogenetics in Episode 3 “Your genes on drugs: context matter” 🎧https://lnkd.in/gQ-7z48Y (listen on our website) 🎧https://lnkd.in/gwdHusVd (listen directly on Spotify) 🗒️ https://lnkd.in/gZkMCvPs (transcript and show notes) #Podcast #Pharmacogenomics (VUSpod is produced by Alex N. Nguyen Ba and team at University of Toronto Mississauga)
This is Iris Cohn, a pharmacist at SickKids. She’s one of the few in Canada to use patients’ genetic data to determine how they’ll react to certain drugs. It’s called pharmacogenetic testing, a precision tool that can determine the right drug and dose for each patient to maximize effectiveness and avoid serious side effects. Though most patients respond to medications as expected, some children are rapid metabolizers, which means they break the drug down too quickly and it has no effect. Others are slow metabolizers, so their body breaks down the drug too gradually, putting the patient at risk for serious side-effects. Analyzing certain genes can reveal this critical knowledge and help personalize prescriptions. Through #PrecisionChildHealth, Iris and her team at The Hospital for Sick Children are working to integrate pharmacogenetic testing into clinical care and help us treat smarter and even predict drug reactions. Precision medicine at its best. #SickKidsVS #SKHealTheFuture
