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The 2024 Nobel Prize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation. By ensuring that only certain genes are activated in each cell type, miRNA regulate cellular differentiation, a process that is fundamental for the development and function of organisms. On the other hand, abnormal regulation by miRNA can lead to cancer or other diseases. More info in the article #NobelPrize #Medicine #Innovation #MedicalResearch #microRNA #Healthcare

🎉 Exciting news! The 2024 Nobel Prize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for their pioneering discovery of microRNA (miRNA). This tiny but mighty molecule regulates gene expression by binding to specific mRNA sequences, affecting protein production and influencing cell development and disease mechanisms. This will transform our understanding of gene regulation and holds significant implications for cancer, genetic disorders, and more. 🌟🔬 #NobelPrize2024 #GeneRegulation #microRNA #ScienceNews

Congratulations to the winners of the 2024 Nobel Prize in Physiology or Medicine, Victor Ambros and Gary Ruvkun, for the discovery of microRNA and its role in post-transcriptional gene regulation!   While microRNA (miRNA) has been around since 1993, its role in gene regulation still impacts the way scientists conduct their research every day.   To briefly explain what microRNAs are, here is a metaphor:   Our bodies function like traffic systems, with microRNA acting as traffic lights and gatekeeper genes or transcriptional factors as the police. Just as traffic lights regulate flow automatically, miRNA controls gene expression after protein transcription. If miRNA regulation fails—like a broken stoplight—the police regulators step in, but less effectively. When miRNA malfunctions, often due to issues in protein transcription, it can lead to diseases like heart disease.   https://lnkd.in/eFU7DuZf

The Nobel Prize in Physiology or Medicine 2024 has been awarded for the groundbreaking discovery of microRNA and its role in post-transcriptional gene regulation! Huge congratulations to Victor Ambros and Gary Ruvkun 🎉 MicroRNAs, a novel class of tiny RNA molecules, have unveiled a whole new dimension to gene regulation, proving to be fundamentally important for the development and functioning of organisms, including humans. This discovery has shed light on a completely new principle of gene regulation crucial for multicellular organisms. Explore Victor and Gary's journey and key publications in the official press release

The 2024 Nobel Prize in Physiology or Medicine has been awarded today to Victor Ambros and Gary Ruvkun for their discovery of microRNA and its role in post-transcriptional gene regulation. They identified microRNA, a novel class of small RNA molecules that play a crucial role in gene expression control. Their seminal discovery was reported in two papers published back-to-back in Cell in 1993 (Lee, Feinbaum and Ambros, 1993; Wightman, Ha and Ruvkun, 1993). It is now known that the human genome encodes over a thousand microRNAs, adding a whole new layer to the complexity of gene regulation. Their remarkable discovery has opened an unexpected and revolutionary dimension to our understanding of biology. Congratulations to the honorees! And of course, a big thank you for their invaluable contributions to RNA research and gene regulation. 👏 For the second year in a row, RNA takes center stage at the Nobel Prize in Medicine. At Sylentis, we proudly celebrate the growing awareness of this vital molecule for life, around which our work revolves. #oligonucleotides #RNA #microRNA #siRNA #Sylentis #NobelPrize 👉 https://lnkd.in/eFU7DuZf

https://lnkd.in/dhs748nW 🎉 Exciting news for the medical community! This year's Nobel Prize in Medicine is awarded to Victor Ambros and Gary Ruvkum for the discovery of microRNA and its role in post-transcriptional gene regulation. 🔬Their discovery of microRNA has transformed our understanding of gene regulation, revealing how these small molecules control essential cellular processes. As someone with a background in researching the role of microRNAs in cancer and autoimmunity, I've seen firsthand how microRNAs dysregulation can drive disease progression by disrupting immune response and cellular balance. This Nobel prize underscores the potential of RNA therapies, that could restore balance in gene regulation offering hope for better treatments. 🌏 A huge leap forward in both basic science and clinical medicine!!

This year’s medicine laureates Victor Ambros and Gary Ruvkun discovered a new principle of gene regulation, mediated by a previously unknown type of RNA, microRNA. They published their results in 1993 but were initially met with almost deafening silence from the scientific community. Although the results were interesting, the unusual mechanism of gene regulation was considered likely irrelevant to humans and other more complex animals. That perception changed in 2000 when Ruvkun's research group published their discovery of another microRNA that was highly conserved and present throughout the animal kingdom. Ruvkun's article sparked great interest, and over the following years, hundreds of different microRNAs were identified. Today, we know that there are more than a thousand genes for different microRNAs in humans, and that gene regulation by microRNA is universal among multicellular organisms. Intriguingly, a single microRNA can regulate the expression of many different genes, and conversely, a single gene can be regulated by multiple microRNAs, thereby coordinating and fine-tuning entire networks of genes. The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation. Learn more Press release: https://bit.ly/3BiM2o9 Advanced information: https://bit.ly/3N6vAtK

This year’s #NobelPrize celebrates #VictorAmbros and #GaryRuvkun for the discovery of microRNAs, a new class of tiny RNA molecules pivotal in gene regulation. Their work sheds light on new horizons in medical research. The breakthrough promises transformative possibilities for personalized medicine. Can't wait to witness how this groundbreaking discovery can impact the landscape of drug development. #NobelPrize #MicroRNAs #MedicalResearch #DrugDevelopment

The 2024 Nobel Prize in Physiology or Medicine is awarded jointly to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation This year’s Nobel Prize honors two scientists for their discovery of a fundamental principle governing how gene activity is regulated. Victor Ambros and Gary Ruvkun were interested in how different cell types develop. They discovered microRNA, a new class of tiny RNA molecules that play a crucial role in gene regulation. Their groundbreaking discovery revealed a completely new principle of gene regulation that turned out to be essential for multicellular organisms, including humans. It is now known that the human genome codes for over one thousand microRNAs. Their surprising discovery revealed an entirely new dimension to gene regulation. MicroRNAs are proving to be fundamentally important for how organisms develop and function.