Beckman Coulter Diagnostics’ Post

Understanding the complex biomarker landscape is key to advancing Alzheimer's disease research. Our recent webinar sheds light on core and emerging biomarkers for amyloid, phospho-tau and neurodegeneration (ATN), offering key insights for those working to identify and validate diagnostic and prognostic biomarkers. Watch the full recording to hear from our scientific leaders. #Alzheimers #Biomarkers #Neurodegeneration #Amyloid

📃Scientific paper: Salivary biomarkers: The early diagnosis of Alzheimer's disease Abstract: The precise identification of Alzheimer's disease and other prevalent neurodegenerative diseases remains a difficult issue that requires the development of early detection of the disease and inexpensive biomarkers that can replace the present cerebrospinal fluid and imaging biomarkers. Blood biomarkers, such as amyloid and neurofilament light, have been emphasized as an important and practical tool in a testing or examination procedure thanks to advancements in ultra‐sensitive detection techniques. Although saliva is not currently being researched for neurodegenerative diseases, it is an important source of biomarkers that can be used for the identification of diseases and has some advantages over other biofluids. While this may be true for most people, getting saliva from elderly people presents some significant challenges. In this overview, we will first discuss how saliva is created and how aging‐related illnesses may affect the amount and kind of saliva produced. The findings support the use of salivary amyloid protein, tau species, and novel biomarkers in the diagnosis of Alzheimer's disease. Continued on ES/IODE ➡️ https://etcse.fr/j7E1 ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you. #alzheimer #science #health

📃Scientific paper: Salivary biomarkers: The early diagnosis of Alzheimer's disease Abstract: The precise identification of Alzheimer's disease and other prevalent neurodegenerative diseases remains a difficult issue that requires the development of early detection of the disease and inexpensive biomarkers that can replace the present cerebrospinal fluid and imaging biomarkers. Blood biomarkers, such as amyloid and neurofilament light, have been emphasized as an important and practical tool in a testing or examination procedure thanks to advancements in ultra‐sensitive detection techniques. Although saliva is not currently being researched for neurodegenerative diseases, it is an important source of biomarkers that can be used for the identification of diseases and has some advantages over other biofluids. While this may be true for most people, getting saliva from elderly people presents some significant challenges. In this overview, we will first discuss how saliva is created and how aging‐related illnesses may affect the amount and kind of saliva produced. The findings support the use of salivary amyloid protein, tau species, and novel biomarkers in the diagnosis of Alzheimer's disease. Continued on ES/IODE ➡️ https://etcse.fr/j7E1 ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you. #alzheimer #science #health

I was encouraged by the increased attention to the role of immune cells in Alzheimer’s disease at #AAIC24. With age and cell damage, microglia and other immune cells may shift from protective to destructive. ICYMI: a new study supported by Cure Alzheimer's Fund funding, and led by Dr. David Holtzman, reveals that mice with loss of brain tissue caused by toxic tau, similar to that in Alzheimer’s, also have more peripheral immune T cells in their brains, attracted there by the brain-resident microglia. Understanding the role of these circulating immune cells in neurodegeneration may lead to new therapeutic strategies. Read more https://lnkd.in/guF_meBB #TCells #ImmuneCells #AlzheimersResearch

📃Scientific paper: Salivary biomarkers: The early diagnosis of Alzheimer's disease Abstract: The precise identification of Alzheimer's disease and other prevalent neurodegenerative diseases remains a difficult issue that requires the development of early detection of the disease and inexpensive biomarkers that can replace the present cerebrospinal fluid and imaging biomarkers. Blood biomarkers, such as amyloid and neurofilament light, have been emphasized as an important and practical tool in a testing or examination procedure thanks to advancements in ultra‐sensitive detection techniques. Although saliva is not currently being researched for neurodegenerative diseases, it is an important source of biomarkers that can be used for the identification of diseases and has some advantages over other biofluids. While this may be true for most people, getting saliva from elderly people presents some significant challenges. In this overview, we will first discuss how saliva is created and how aging‐related illnesses may affect the amount and kind of saliva produced. The findings support the use of salivary amyloid protein, tau species, and novel biomarkers in the diagnosis of Alzheimer's disease. Continued on ES/IODE ➡️ https://etcse.fr/j7E1 ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you. #alzheimer #science #health

🧠 Transforming Alzheimer’s Diagnostics: NULISAseq CNS Disease Panel 120 🧬 Exciting news from the University of Pittsburgh! Researchers have validated a new blood test, the NULISAseq CNS Disease Panel 120, capable of measuring over 100 biomarkers for Alzheimer’s disease (AD). This innovative approach promises to revolutionize early detection by identifying neuroinflammation and brain blood vessel dysfunction through a simple blood draw—significantly reducing the need for invasive procedures. Dr. Thomas Karikari states, “Alzheimer’s disease should not be looked at through one single lens.” This comprehensive panel could enhance our ability to identify at-risk individuals before cognitive symptoms emerge. We look forward to seeing how this advancement will shape the future of AD diagnostics! 🔗 For more details, check out the full study in Molecular Neurodegeneration. - https://hubs.li/Q02YbWlZ0 #AlzheimersDisease #HealthcareInnovation #BioTouch

📃Scientific paper: Salivary biomarkers: The early diagnosis of Alzheimer's disease Abstract: The precise identification of Alzheimer's disease and other prevalent neurodegenerative diseases remains a difficult issue that requires the development of early detection of the disease and inexpensive biomarkers that can replace the present cerebrospinal fluid and imaging biomarkers. Blood biomarkers, such as amyloid and neurofilament light, have been emphasized as an important and practical tool in a testing or examination procedure thanks to advancements in ultra‐sensitive detection techniques. Although saliva is not currently being researched for neurodegenerative diseases, it is an important source of biomarkers that can be used for the identification of diseases and has some advantages over other biofluids. While this may be true for most people, getting saliva from elderly people presents some significant challenges. In this overview, we will first discuss how saliva is created and how aging‐related illnesses may affect the amount and kind of saliva produced. The findings support the use of salivary amyloid protein, tau species, and novel biomarkers in the diagnosis of Alzheimer's disease. Continued on ES/IODE ➡️ https://etcse.fr/j7E1 ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you. #alzheimer #science #health

Aging-us.com ("Aging (Albany NY)" by Medline/PubMed, "Aging-US" by Web of Science) is a traditional, peer-reviewed, open-access journal covering all areas of research on aging & age-related diseases—including cancer & COVID-19 vulnerability as an age-dependent syndrome

March is MS Awareness Month Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system. The theme for World MS Day 2024-2025 is diagnosis. Most people with MS are diagnosed between the ages of 20 and 40. Molecular biomarkers can complement MRI and clinical markers in different phases of MS disease and these include diagnosis and prognosis of the disease. #msawarenessmonth #NeurodegenerativeDiseases #MolecularTesting

Welcome back to Pub Crawl! Today, we are highlighting a comparative study evaluating key plasma phosphorylated tau 217 (p-tau217) assays for the detection of Alzheimer’s disease, featuring data from Lund University.   🔬 Pub Crawl #4: A comprehensive head-to-head comparison of key plasma phosphorylated tau 217 biomarker tests   👉 Crawl the pub: https://lnkd.in/gqg9TdSQ   Stay tuned for more scientific highlights! Follow us to keep up with the series. #Alzheimers #Biomarkers #NeurodegenerativeDiseases