Better Bioeconomy’s Post

Protein engineering has always been hindered by slow, costly processes—until now. Cradle’s generative AI platform is rewriting the rules. By combining cutting-edge AI with a dual-model system, Cradle optimizes key properties like stability and manufacturability in ways that were previously unimaginable. Experimental cycles are slashed from 10–20 rounds to just 3–4, reducing costs by up to 90% and boosting enzyme activity by 4×—all in record time. Cradle isn’t just about efficiency; it’s about empowerment. The company aims to equip one million scientists with its platform, sparking breakthroughs across fields. In healthcare, this means accelerating the development of novel therapeutics, vaccines, and diagnostics, potentially reducing the time and cost to bring life-saving treatments to market. In agriculture, it offers tools to engineer improved enzymes and proteins for crop protection and sustainable food solutions, addressing global challenges like food security and environmental impact. However, scaling such transformative technology and ensuring its adaptability across diverse scientific applications pose significant challenges. Despite these hurdles, Cradle remains focused on overcoming them and pushing the boundaries of what’s possible in biotechnology. With $73M in Series B funding and collaborations with Novo Nordisk and Johnson & Johnson, Cradle is on track to not only push the limits of innovation but also profoundly reshape the future of human and planetary health.

𝐂𝐨𝐦𝐩𝐥𝐞𝐭𝐞 𝐆𝐮𝐢𝐝𝐞 𝐨𝐟 " 𝐔.𝐒. 𝐁𝐢𝐨𝐭𝐞𝐜𝐡𝐧𝐨𝐥𝐨𝐠𝐲" 𝐃𝐨𝐰𝐧𝐥𝐨𝐚𝐝 𝐅𝐫𝐞𝐞 𝐒𝐚𝐦𝐩𝐥𝐞 𝐑𝐞𝐩𝐨𝐫𝐭 𝐇𝐞𝐫𝐞 | 𝐈𝐦𝐦𝐞𝐝𝐢𝐚𝐭𝐞 𝐃𝐞𝐥𝐢𝐯𝐞𝐫𝐲 𝐀𝐯𝐚𝐢𝐥𝐚𝐛𝐥𝐞 : ( https://lnkd.in/dfU4NxdE )   The U.S. biotechnology market size was estimated at USD 552.49 billion in 2023 and is projected to hit around USD 1,794.11 billion by 2033, growing at a CAGR of 12.5% during the forecast period from 2024 to 2033. Government support plays a major role in propelling market growth, focusing on modernizing regulatory frameworks, enhancing approval processes and reimbursement policies, and standardizing clinical studies. The National Science Foundation (NSF) and Synthetic Biology Engineering Research Center (SynBERC) are responsible for conducting regular evaluations of synthetic biology. Biotechnology applications are experiencing a surge in market revenue thanks to the growth of personalized medicine and the development of orphan drug formulations. This has resulted in the emergence of many new and innovative biotech firms, contributing to the industry's expansion. The U.S. accounted for over 35.6% of the global biotechnology market 2023. The increasing demand for agricultural products like wheat, rice, and beans, driven by population growth, highlights the importance of biotechnology-based solutions. Scientists focus on advanced agricultural technologies through extensive research and development (R&D) to address challenges such as pest attacks, limited land availability, and water scarcity. Moreover, investments in agriculture R&D, exemplified by companies like Loopworm and initiatives like the USD 101 million investment by Unilever and others in regenerative agriculture, propel market growth. Supportive government guidelines, particularly in synthetic biology, and the decreasing costs of DNA sequencing are also significant drivers of the biotechnology market's expansion. 𝐊𝐞𝐲 𝐓𝐚𝐤𝐞𝐚𝐰𝐚𝐲𝐬: ➡DNA sequencing dominated this market and held the highest revenue market share of 18% in 2023 ➡ The others’ segment is anticipated to grow at the fastest CAGR of 28.1% during the forecast period. ➡ The health segment dominated the market and accounted for the largest revenue market share of 44.13% in 2023. ➡ Bioinformatics is expected to witness the fastest growth, with a CAGR of 17.2% during the forecast period. 𝐅𝐨𝐫 𝐌𝐨𝐫𝐞 𝐈𝐧𝐟𝐨𝐫𝐦𝐚𝐭𝐢𝐨𝐧- https://lnkd.in/dfU4NxdE

𝐂𝐨𝐦𝐩𝐥𝐞𝐭𝐞 𝐆𝐮𝐢𝐝𝐞 𝐨𝐟 " 𝐔.𝐒. 𝐁𝐢𝐨𝐭𝐞𝐜𝐡𝐧𝐨𝐥𝐨𝐠𝐲" 𝐃𝐨𝐰𝐧𝐥𝐨𝐚𝐝 𝐅𝐫𝐞𝐞 𝐒𝐚𝐦𝐩𝐥𝐞 𝐑𝐞𝐩𝐨𝐫𝐭 𝐇𝐞𝐫𝐞 | 𝐈𝐦𝐦𝐞𝐝𝐢𝐚𝐭𝐞 𝐃𝐞𝐥𝐢𝐯𝐞𝐫𝐲 𝐀𝐯𝐚𝐢𝐥𝐚𝐛𝐥𝐞 : ( https://lnkd.in/dijFgzMM )   The U.S. biotechnology market size was estimated at USD 552.49 billion in 2023 and is projected to hit around USD 1,794.11 billion by 2033, growing at a CAGR of 12.5% during the forecast period from 2024 to 2033. Government support plays a major role in propelling market growth, focusing on modernizing regulatory frameworks, enhancing approval processes and reimbursement policies, and standardizing clinical studies. The National Science Foundation (NSF) and Synthetic Biology Engineering Research Center (SynBERC) are responsible for conducting regular evaluations of synthetic biology. Biotechnology applications are experiencing a surge in market revenue thanks to the growth of personalized medicine and the development of orphan drug formulations. This has resulted in the emergence of many new and innovative biotech firms, contributing to the industry's expansion. The U.S. accounted for over 35.6% of the global biotechnology market 2023. The increasing demand for agricultural products like wheat, rice, and beans, driven by population growth, highlights the importance of biotechnology-based solutions. Scientists focus on advanced agricultural technologies through extensive research and development (R&D) to address challenges such as pest attacks, limited land availability, and water scarcity. Moreover, investments in agriculture R&D, exemplified by companies like Loopworm and initiatives like the USD 101 million investment by Unilever and others in regenerative agriculture, propel market growth. Supportive government guidelines, particularly in synthetic biology, and the decreasing costs of DNA sequencing are also significant drivers of the biotechnology market's expansion. 𝐊𝐞𝐲 𝐓𝐚𝐤𝐞𝐚𝐰𝐚𝐲𝐬: ➡DNA sequencing dominated this market and held the highest revenue market share of 18% in 2023 ➡ The others’ segment is anticipated to grow at the fastest CAGR of 28.1% during the forecast period. ➡ The health segment dominated the market and accounted for the largest revenue market share of 44.13% in 2023. ➡ Bioinformatics is expected to witness the fastest growth, with a CAGR of 17.2% during the forecast period. 𝐅𝐨𝐫 𝐌𝐨𝐫𝐞 𝐈𝐧𝐟𝐨𝐫𝐦𝐚𝐭𝐢𝐨𝐧- https://lnkd.in/dijFgzMM

Cyclodextrins a "super molecules" Cyclodextrins are cyclic oligosaccharides composed of glucose units linked by α-1,4-glycosidic bonds. Their structure forms a toroidal or doughnut-shaped molecule with: Hydrophobic interior: This allows them to encapsulate non-polar molecules. Hydrophilic exterior: This makes them soluble in water. The most common types are: α-Cyclodextrin: Six glucose units. β-Cyclodextrin: Seven glucose units. γ-Cyclodextrin: Eight glucose units. Why It's a "Super Molecule" Encapsulation Capability: Cyclodextrins can form inclusion complexes by trapping guest molecules in their hydrophobic cavity. This property is used for stabilizing, solubilizing, and protecting various compounds. Environmental Friendliness: They are biodegradable, non-toxic, and derived from starch, making them an eco-friendly option in various industries. Versatility in Applications: Pharmaceuticals: Enhance drug solubility, stability, and bioavailability. Food Industry: Mask unpleasant tastes or odors and stabilize flavors. Cosmetics: Stabilize active ingredients and improve delivery. Environmental Science: Remove organic pollutants from water through encapsulation. Chemical Modifications: Cyclodextrins can be chemically modified (e.g., methylation, hydroxypropylation) to tailor their properties for specific applications. Self-Assembly: Cyclodextrins can act as building blocks for supramolecular assemblies, enabling the creation of nanomaterials, sensors, and drug delivery systems. Scientific and Industrial Impact Cyclodextrins exemplify the principles of supramolecular chemistry, where molecular recognition and host-guest interactions are key. Their use has revolutionized several fields, demonstrating the power of molecular engineering. If you'd like to explore specific applications or dive deeper into their chemistry, contact to CarboHyde

Enzymes are everywhere, including in nature. They are an essential part of the functioning of our bodies. Enzymes can be used as medicines. They also have additional applicaitons in industrial and agricultural uses. Allozymes is a company which is developing a method for discovering brand new enzymes. In a lab, it’s possible to screen hundreds of enzymes in a single day. Their device makes it possible to screen millions per day because of a microchemistry based approach they have developed for screening enzymes This is a real innovation that is helping new discoveries to be made! #stem #tech #biotech #biotechnology https://lnkd.in/gygmbKDS

Hi Everyone I am going to share my Article On The Topic Biotechnology #snsinstitution #snsdesginthinking #designthinkers . . . Term biotechnology was first used by Károly Ereky in 1919to refer to the production of products from raw materials with the aid of living organisms. The core principle of biotechnology involves harnessing biological systems and organisms, such as bacteria, yeast, and plants, to perform specific tasks or produce valuable substances. Biotechnology had a significant impact on many areas of society, from medicine to agriculture to environmental science. One of the key techniques used in biotechnology is genetic engineering, which allows scientists to modify the genetic makeup of organisms to achieve desired outcomes. This can involve inserting genes from one organism into another, and consequently, create new traits or modifying existing ones. Other important techniques used in biotechnology include tissue culture, which allows researchers to grow cells and tissues in the lab for research and medical purposes, and fermentation, which is used to produce a wide range of products such as beer, wine, and cheese. The applications of biotechnology are diverse and have led to the development of products like life-saving drugs, biofuels, genetically modified crops, and innovative materials.It has also been used to address environmental challenges, such as developing biodegradable plastics and using microorganisms to clean up contaminated sites.

𝗧𝗵𝗲 𝗝𝗼𝘆 𝗮𝗻𝗱 𝗣𝗲𝗿𝗶𝗹 𝗼𝗳 𝗧𝗶𝗻𝗸𝗲𝗿𝗶𝗻𝗴 Biotechnology has a reputation that’s as intriguing as it is ominous. That’s understandable—today, we’re essentially tinkering with the source code of life. Biotechnology had humble beginnings, rooted in ancient agricultural practices. Selective breeding was our first venture into biotechnology. Dogs, anyone? Every biological process we’ve developed, starting with fermentation, has furthered biotechnology’s reach. Think bread, cheese, beer and and a chilled Grüner Veltliner. The discovery of DNA transformed biotechnology, it gave us the tools to hack evolution. Today, we use our endless curiosity to experiment with gene manipulation in labs, where we cut, copy, and modify DNA with precision. Recently, the focus has turned to RNA, the powerful molecules that can switch DNA on or off. This has opened brand new scientific areas, especially in treating complex diseases like cancer. Tinkering with DNA and the famous CRISPR has other promising areas. One of my favorite is the efforts to create plastic-eating bacteria, a possible solution to environmental waste. 𝗧𝗔𝗥𝗚𝗘𝗧 𝟭𝟳 𝗦𝘁𝗿𝗲𝗻𝗴𝘁𝗵𝗲𝗻 𝗕𝗶𝗼𝘀𝗮𝗳𝗲𝘁𝘆 𝗮𝗻𝗱 𝗗𝗶𝘀𝘁𝗿𝗶𝗯𝘂𝘁𝗲 𝘁𝗵𝗲 𝗕𝗲𝗻𝗲𝗳𝗶𝘁𝘀 𝗼𝗳 𝗕𝗶𝗼𝘁𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝘆 The uses of biotechnology are ancient and brand new, amazing and dangerous. This target focus on to two key aspects: A. Keeping it safe (you know, whatever happened or didn't happen in Wuhan), and B. Sharing its benefits equitably (think of life-saving innovations like penicillin, insulin, and the mRNA COVID-19 vaccines). The design of this made us scratch our heads. We wanted to show it safe and contained and, at the same time, shared. They merged when Christina drew a network of shared information that also formed an shield that keeps us safe. Download all the icons here: https://lnkd.in/ds9-BYBT

Application of Biotechnology 1. Medicine and Healthcare: Biotechnology has made a significant impact on the field of medicine and healthcare. It has enabled the development of new treatments and drugs, improved diagnostic techniques, and made gene therapy a possibility. 2. Agriculture: Biotechnology has revolutionized agriculture by developing genetically modified crops that are more resistant to pests and diseases, have increased yield and nutritional value, and can grow in harsh environments. 3. Environmental Conservation: Biotechnology has played a vital role in environmental conservation by developing sustainable solutions for waste management, pollution control, and bioremediation of contaminated sites. 4. Industrial Production: Biotechnology has been used to improve industrial processes, such as fermentation, to produce enzymes, chemicals, and biofuels. 5. Forensics: Biotechnology has been instrumental in forensic science by aiding in the identification of suspects through DNA analysis and helping to solve crimes. 6. Genetic Engineering: Biotechnology has allowed scientists to manipulate the genetic makeup of organisms to produce desired traits. This has led to the development of disease-resistant crops, enhanced livestock, and new medical treatments. 7. Biopharmaceuticals: Biotechnology has enabled the production of biopharmaceuticals, which are drugs made from biological sources. 8. Personalized Medicine: Biotechnology has made personalized medicine a reality by allowing for the identification of genetic markers that can predict an individual's response to certain treatments. 9. Bioinformatics: Biotechnology has played a crucial role in the field of bioinformatics, which involves the use of computer technology to analyze and interpret biological data. 10. Food and Beverage Industry: Biotechnology has had a significant impact on the food and beverage industry by developing methods for food processing, preservation, and quality control.

𝗧𝗼𝗽 𝗕𝗶𝗼𝘁𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝘆 𝗜𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝗼𝗻𝘀! 🌟 From genetically engineered plants to cutting-edge protein synthesis, these breakthroughs are making waves in the science world. Here are some highlights: 1. 𝗚𝗲𝗻𝗲𝘁𝗶𝗰𝗮𝗹𝗹𝘆 𝗘𝗻𝗴𝗶𝗻𝗲𝗲𝗿𝗲𝗱 𝗣𝗹𝗮𝗻𝘁𝘀 🌾    - Scientists at the University of Pennsylvania have developed plants that can resist environmental stresses by overexpressing a gene called GRP8. This helps plants absorb more nutrients and water, reducing the need for fertilizers! 🌿 2. 𝗖𝗲𝗹𝗹-𝗳𝗿𝗲𝗲 𝗣𝗿𝗼𝘁𝗲𝗶𝗻 𝗣𝗿𝗼𝗱𝘂𝗰𝘁𝗶𝗼𝗻 🧬    - Researchers at the Australian National University have created a new method for producing proteins without living cells, using eCells. This makes protein production faster and more cost-effective! 🔬 3. 𝗡𝗮𝗻𝗼𝗽𝗮𝗿𝘁𝗶𝗰𝗹𝗲𝘀 𝗳𝗼𝗿 𝗔𝗻𝘁𝗶𝗺𝗶𝗰𝗿𝗼𝗯𝗶𝗮𝗹 𝗧𝗿𝗲𝗮𝘁𝗺𝗲𝗻𝘁𝘀 💊    - SynCell Biotechnology is using selenium nanoparticles from MRSA bacteria to create wound dressings that target infections without harming beneficial bacteria. Say goodbye to antibiotic resistance! 🚑 4. 𝗕𝗶𝗼𝗱𝗲𝗴𝗿𝗮𝗱𝗮𝗯𝗹𝗲 𝗣𝗹𝗮𝘀𝘁𝗶𝗰𝘀 🌍    - A new strain of E. Coli developed by scientists at SUNY can produce tailor-made biodegradable plastics, helping reduce plastic waste and its environmental impact. ♻️ 5. 𝗗𝗶𝘀𝘂𝗹𝗽𝗵𝗶𝗱𝗲 𝗕𝗼𝗻𝗱𝗲𝗱 𝗣𝗿𝗼𝘁𝗲𝗶𝗻𝘀 💉    - Oulu University has developed a system to produce stable, disulphide bonded proteins in bacteria, making protein production more efficient and scalable for various industries! ⚗️ #Biotech #Innovation #Sustainability #Healthcare #EnvironmentalScience #FutureTech #GreenScience #ProteinSynthesis #BiodegradablePlastics #Nanotechnology #GeneticEngineering

"Biotechnology Innovations: Towards Sustainable Health and a Secure Future" - ## Introduction: The Importance of Biotechnology in the Modern Era Biotechnology is one of the fundamental pillars supporting progress in many fields, from healthcare to agriculture and environmental protection. With the increase in chronic disease rates and environmental challenges, it has become essential to rely on innovative scientific solutions to ensure a healthy and sustainable future. Recent statistics indicate that the global biotechnology market may reach $727.1 billion by 2025, reflecting a growing trend in this field. The qualitative leaps in areas such as genomics, the development of biological drugs, and agricultural technologies illustrate the shift towards using technology to address contemporary challenges. In this context, the article seeks to explore the key innovations in biotechnology and how they can contribute to improving quality of life and achieving environmental sustainability.## Innovations in Healthcare Amid the rapid medical innovations, biotechnology is a cornerstone in the development of new treatments and drugs that target diseases more precisely. Techniques such as gene editing are among the most prominent advancements, utilizing tools like CRISPR to modify genes associated with genetic diseases. This allows for the correction of genetic defects before symptoms appear, contributing to a reduction in the incidence of both rare and common diseases. Moreover, biotechnology enables the development of immunotherapies, such as enhanced therapy, which works to bolster the immune system’s ability to combat cancer. By using genetically modified antibodies, scientists can improve the body’s response to tumors in ways that were previously unimaginable. This has transformed the landscape of cancer treatment, providing hope to many patients. ## Agricultural Applications of Biotechnology Biotechnology also significantly contributes to improving agricultural productivity by developing pest- and disease-resistant crops. By utilizing modern technologies such as genetic engineering, it is possible to create plant varieties that can withstand harsh climatic conditions and require less water and other agricultural resources. This positively affects food security amid a growing population and climate change. Additionally, biotechnology can be used to produce biostimulants that enhance plant growth and increase their ability to absorb nutrients. Thanks to these innovations, it is possible to reduce reliance on harmful chemicals, contributing to the health of the environment and biodiversity. ## Environmental Protection Biotechnology plays a pivotal role in environmental protection strategies by developing innovative solutions to address environmental problems. For example, genetically modified microbes are used to clean soil and water from toxic pollutants, aiding in the restoration of damaged ecosystems. This field is known as environmental ...