BMC’s Post

As tumoroid culture becomes more accessible, easy to use, and standardized, we anticipate that they will be widely adopted in cancer research due to their increased biological relevance compared to spheroids generated from immortalized cancer cell lines

Immortalized cancer cell lines are widely available, and many assays and cell stains developed for 2D monolayers translate well to spheroid models

"Scientists have developed a booster treatment that could improve the efficiency of existing CAR T-cell therapies for cancer by addressing their major shortcoming: a high rate of relapse, even in patients whose cancer goes into full remission. The team created the CAR-Enhancer (CAR-E) therapeutic platform to spur CAR T cells to be more active and persist longer in the body, enabling them to remain in battle mode until all tumor cells are eliminated. The platform also prompts CAR T cells to form a memory of the cancer cells so they can spring back into action if the cancer recurs." https://lnkd.in/edndDahW

As tumoroid culture becomes more accessible, easy to use, and standardized, we anticipate that they will be widely adopted in cancer research due to their increased biological relevance compared to spheroids generated from immortalized cancer cell lines

As tumoroid culture becomes more accessible, easy to use, and standardized, we anticipate that they will be widely adopted in cancer research due to their increased biological relevance compared to spheroids generated from immortalized cancer cell lines Ask me about how we can support your 3D research needs! #oncopro #tumoroids

A study from Tampere University, published in Nature Communications, highlights a link between immunosuppression and a specialized epithelial subtype in prostate cancer. Analyzing 120 patients, researchers found that club-like epithelial cells, which resist androgen deprivation therapy, interact with myeloid-derived suppressor cells, leading to treatment resistance. This interaction is associated with poor prognosis in advanced cases. The study emphasizes the need for innovative strategies to overcome treatment resistance. Utilizing advanced spatial technologies, the research offers new insights into cell interactions within the tumor microenvironment, potentially guiding future therapeutic approaches.

🔬 Exploring the differences between cancer spheroids and organoids! Spheroids offer a simplified, cost-effective 3D model, while tumoroids provide a more accurate, patient-specific representation of tumors. Discover their unique strengths and applications in advancing cancer research.

🔬 Exploring the differences between cancer spheroids and organoids! Spheroids offer a simplified, cost-effective 3D model, while tumoroids provide a more accurate, patient-specific representation of tumors. Discover their unique strengths and applications in advancing cancer research.

🔬 Exploring the differences between cancer spheroids and organoids! Spheroids offer a simplified, cost-effective 3D model, while tumoroids provide a more accurate, patient-specific representation of tumors. Discover their unique strengths and applications in advancing cancer research.

🔬 Exploring the differences between cancer spheroids and organoids! Spheroids offer a simplified, cost-effective 3D model, while tumoroids provide a more accurate, patient-specific representation of tumors. Discover their unique strengths and applications in advancing cancer research.