Bruker Biosensors’ Post

Spatial biology companies Vizgen and Ultivue are merging amid Vizgen's ongoing lawsuits with 10x Genomics. Ultivue CEO Rob Carson will lead the combined company, which will go by the name Vizgen. It will continue offering both spatial proteomics (Ultivue) and spatial transcriptomics (Vizgen) tools. Former Vizgen CEO Terry Lo will remain on the board. Read more in my story for Endpoints News: https://lnkd.in/eDt5jMZN #spatialbiology #genomics #spatialbio #spatialproteomics #proteomics #spatialtranscriptomics #transcriptomics #singlecell #singlecellseq #RNAseq #sequencing

Data Art: Coincidence or Artifact? There is something exciting in the HDX-MS data from my recent experiment! The kinetic profile of two different protein samples shows a surprising pattern resembling a cyclohexane ring. It's amazing how data can self-organize into such stable molecular structures. 😅 Fascinating correlation between protein dynamics and the beauty of scientific data visualization! However, I'd like to point out a small issue: the peaks in this mass spec analysis need to be manually assigned for accurate deuterium uptake quantification, something that should be automatically done by the software. Hoping Waters Corporation will consider updating DynamX to streamline this process in future versions, as it would save a lot of time and improve accuracy. Despite this, I'm excited about the insights this data reveals on the dynamX of protein. #hdxms #chemistry #protein #biophysics #structuralbiology

I was on a very interesting panel about the democratization of science, about communicating science to the people, about synthetic biology, and all sorts of cool, interrelated concepts. It was also filmed at a really neat studio space at Concordia University. If you have any interest in these topics, go watch the video now! #scicomm #syntheticbiology #synbio #sciencejournalism #trust #biology #sciencemuseum #scienceeducation https://lnkd.in/eQDmcduh

We surveyed 1,100 executives across various industries and found that around half believe that #EngineeringBiology will disrupt their industry within the next five years. This explains why 96% of organizations are embracing engineering biology. With 40% at an exploratory stage — and 56% engaging more actively in experimentation, pilots, or scaled deployments. Download our full report now to find out more: bit.ly/3Mv86yo #EngineeringBiology #DNA #SyntheticBiology #Innovation

What does it take to run a core facility? Why not ask Erin Telley Tranfield and Pablo Hernández-Varas, the new heads of our BioImaging Core? In this interview (👉 https://lnkd.in/e5_3tXKj) we talk to them about their journey, their vision, and the advice they have for young scientists.

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Scientific progress shouldn't be limited by cell line challenges. Our new poster explores how CellRaft® Technology helped six researchers overcome unique obstacles. Get inspired and unlock your research potential! DOWNLOAD POSTER: https://lnkd.in/eH2yZHkK hashtag #CellLineDevelopment hashtag #CellRaftTechnology hashtag #SenescentCells hashtag #SingleCellAnalysis hashtag #SingleCellTech hashtag #CellularHeterogeneity hashtag #SingleCellResearch hashtag #CellularBiology

Happy #DNADay, a great opportunity to recognize the profound impact of DNA on science, medicine and society and celebrate its future. We're committed to propelling biology from the era of reading DNA to the era of writing DNA without limitations. Here's to pushing the boundaries of DNA synthesis to unlock new possibilities! #DNAsynthesis #longDNA #Ansamers #biotech #synbio #SyntheticDNA #DNAInnovation #complexDNA #customDNA #AnsamerAnswers.

Yesterday marked the end of NanoString Technologies, Inc. 20-year journey as an independent company and my 14-year tenure as CEO of NanoString. We have found in Bruker a wonderful home for the enterprise so many people worked so hard to build. I know our customers will be well cared for, and my colleagues will continue our mission to Map the Universe of Biology. I have been reflecting on how much the NanoString team has accomplished. I joined a scrappy team of about 70 NanoStringer. Our nCounter gene expression platform was early in its life cycle, in a few dozen labs and generating just $12M in annual revenue. Our goal was clear: to increase nCounter adoption in research labs and advance it into clinical diagnostics. We succeeded and then some! We launched four generations of nCounter instruments and a much-emulated menu of RNA panels that powered immuno-oncology research. We took the Prosigna Breast Cancer Assay through FDA review, into treatment guidelines, and gained reimbursement.  Today, nCounter is the market leader in mid-plex gene expression, with >1,100 installed units and annual revenue >$60 million. Our scientific customers have used it to publish more than 7,000 peer-reviewed papers, and their scientific output continues to exceed 1,000 studies per year. Challenged by our scientific customers to advance our technology to reveal the locations of RNA and protein within tissue, we pioneered a new field and decided to call it “Spatial Biology.” We invented two revolutionary platforms: the GeoMx Digital Spatial Profiler and the CosMx Spatial Molecular Imager. Recently, we demonstrated the holy grail of biology: the ability to visualize the RNA from every gene in the genome, cell-by-cell, in an intact tissue sample. Just four years after the first instrument shipped, our Spatial Biology franchise generated annual revenue exceeding $100 million. Throughout this journey, we opted for a “big tent” strategy of shared success with many leading companies in biotechnology. We built cancer diagnostics with Celgene, Medivation, Astellas Pharma, Merck, and Veracyte, Inc.. We partnered with Lam Research to develop the CosMx platform. And we created a leading spatial biology ecosystem through partnerships with abcam, @AWS, Bio-Techne, Illumina, Leica Biosystems, NVIDIA, Visiopharm and others. These achievements were made possible through the hard work of hundreds of colleagues - extraordinarily gifted scientific, commercial, manufacturing, finance, HR, IT, lawyers, and Board members. Together, we made it from struggling start-up to global life sciences brand and formed friendships within the company, with our customers, and across our industry that will last a lifetime. To my NanoString teammates past and present: you have much to be proud of. I hope you carry with you our culture of Ambition, Authenticity, Customer-focus, Grit, and Ingenuity to whichever organization you are connected to in the future. We will always be NanoStringers!

Discover the art of determining cell confluency! Learn how to read visual cues and hone your skills with practice. Explore more cell culture practices on our website: www.lablife.video. #CellConfluency #Microscopy #ImagingSoftware #CellCulture #Science #Research #CellCulture #LabLife