Caitlyn Fastenau’s Post

Additionally, in 2019, at the Third International Congress of Biomedical Sciences, together with my esteemed colleague, Ms. Seyedeh Kosar Mahmoudi, we presented a therapeutic approach for Huntington's disease using molecular biology tools based on our own theory. #neurodegenerative

Journal of Experimental Medicine (JEM) is pleased to present a collection showcasing the breadth of JEM's interests with recent authoritative reviews of different aspects of the immune system. We bring you scholarly overviews of the latest research on topics such as thymus and T cell development, B cell tolerance, tissue repair, nutrient signaling integration, granulocyte and ILC biology, and self vs. non-self recognition. https://hubs.la/Q02YPZT00

AFAR is pleased to announce a recipient of the second cohort of the Hevolution/AFAR New Investigator Awards in Aging Biology and Geroscience Research: Rebecca Voorhees, PhD. Dr. Voorhees of Caltech will research "Inhibition of MTCH2 as a novel modality for ageing therapy." Learn more about her AFAR-supported research here: https://lnkd.in/e6zDzxeq #protein #CellularSenescence #mitochondria

🌟 Join Our Spatial Expert Insights Webinar! 🌟 Discover how spatial profiling can revolutionize obesity research by detecting diverse mRNA markers and short targets at single-cell resolution. Gain cutting-edge insights into: 🔬 Advanced spatial profiling techniques 🧬 Detecting key markers linked to obesity 📊 Leveraging single-cell resolution for impactful results Don't miss this opportunity to learn from industry experts and elevate your research. 📅 Save the date and unlock the future of spatial biology. #SpatialBiology #ObesityResearch #Webinar #InnovationsInScienc https://lnkd.in/dtMmpvpD

Exciting News! Apollo Hospitals Educational and Research Foundation presents AHERF Connect Webinar 4 featuring an insightful talk by Dr. Adinarayana Marada, Research Scientist at Albert Ludwig The University of Freiburg, Germany! Topic: Regulation of Mitochondrial Biogenesis in Health and Disease Date: September 10, 2024 Time: 11:00 AM to 12:00 PM IST Joining Link: https://lnkd.in/eqKAGSm2 Dr. Marada, with over 13 years of research experience and a Ph.D. in Mitochondrial Biology from the University of Hyderabad, will delve into the latest advancements in mitochondrial science. His work has been featured in leading journals such as Nature Communications and PLoS Genetics. Key Takeaways: Regulatory Mechanisms: Insights into how mitochondrial protein biogenesis is regulated. Cellular Signaling: The interplay between mitochondrial function and cellular needs. Research Impact: How recent advancements influence our understanding of health and disease. Join us for an enlightening session that promises to enhance your knowledge of mitochondrial biology. Looking forward to your participation! #MitochondrialBiology #ResearchTalk #HealthAndDisease #CellBiology #AHERF #ScientificResearch #Webinar #Mitochondria

As we age, the intricate balance of protein homeostasis (proteostasis) — the system responsible for maintaining cellular health by ensuring proteins are correctly folded— begins to falter. This decline leads to the accumulation of toxic protein aggregates, a hallmark and an underlying cause of neurodegenerative diseases such as Alzheimer’s disease. A new study led by The Hebrew University of Jerusalem researchers Prof. Ehud Cohen and the student Huadong Zhu from the Department of Biochemistry and Molecular Biology at the Institute for Medical Research Israel–Canada (IMRIC) in collaboration with the lab of Dr. Yonatan Tzur of the Alexander Silberman institute of Life Science, sheds light on a promising new way to address this issue, with implications that extend far beyond basic research.

🌿 New Research Highlight in Current Issues in Molecular Biology! Discover the novel protective effects of Chrysanthemum coronarium L. (CC) extract on preventing premature senescence in human endothelial cells! Mi Jeong Sung and Ae Sin Lee's study reveals that CC extract reduces oxidative stress and boosts nitric oxide production, protecting against aging-related vascular dysfunction. The research identifies key roles of eNOS and SIRT1 in this protective mechanism. 🔍 Full paper: https://lnkd.in/eA7Z5aBz #EndothelialHealth #VascularAging #ChrysanthemumExtract #OxidativeStress #eNOS #SIRT1 #MolecularBiology

📢 The second edition of 'The ageing genome: from mechanisms to disease' has just opened for registrations 🙌 #EESAgeing will bring together an all-new, international line-up of speakers to continue the exchange on the basic/mechanistic aspects of chromosome biology with the applied and emerging field of ageing sciences 🕰️🧬 Session topics: 🟠 Endogenous and metabolic genotoxins 🟠 Aneuploidy 🟠 Loss of proteostasis 🟠 Telomere dysfunction 🟠 Age related disease 🟠 Model systems for ageing research 🟠 Senescence responses 🟠 Chromatin stability and epigenetics 🟠 Mitochondrial stability as a function of ageing 🟠 DNA repair during the ageing process Join us and submit your abstract today! 👉🏼 s.embl.org/ees25-05 📅 10 – 13 June 2025 📍 EMBL Heidelberg and Virtual 📜 Submit abstract by 18 March 2025

And also see our chapter in the same book, our chapter is "Evidence of mitochondrial dysfunction in ALS and methods for measuring in model systems" https://lnkd.in/gUJawyBc

Have five minutes to learn some groundbreaking science?⏲️ Dive into our latest summary of the phenomenal 2023 research by Loupy et al., published in The Lancet, on the early immune response after the first-ever pig-to-human kidney xenotransplantation. 🐖 See how molecular tools like the nCounter Analysis System and GeoMx DSP unveiled antibody-mediated rejection and the complex biological processes driving it. Explore our in-depth breakdown of this study here: https://bit.ly/3UFTv7H #OrganTransplantResearch #nCounter #SpatialBiology