Caleva’s Post

Thermal melt is a powerful tool in the biochemistry and pharmaceutical industries. Get in touch with me or my colleagues Maninder Singh Karir Clement Elliott Ralph Vokes if you would like to know more about how we can help you.

Process for Reducing Subvisible Particles in a Pharmaceutical Formulation A U.S. Patent for a "Process for Reducing Subvisible Particles in a Pharmaceutical Formulation" was awarded to Regeneron on August 27th, 2024. The present invention provides a stable protein composition containing a surfactant and having less than 400 subvisible particles of 10 microns or greater diameter per container, or less than 10,000 subvisible particles of 2 microns or greater per container. A method of manufacturing such a stable protein composition is disclosed, which includes a unit of operation that removes or decreases an esterase activity that degrades the surfactant. https://lnkd.in/gxXnYsee #aspenalert #biotech #bioprocess

Are you trying to improve the solubility of APIs? Then you should have a look at this interesting publication! #dendrimers #nanotechnology #biomedicalapplication

Apex® Biological Indicator (BI) products are designed specifically to meet the unique needs of the pharmaceutical, food, and medical device industries utilizing vaporized hydrogen peroxide (VH2O2) decontamination. The Apex® product line offers: The most resistant strain to VH202 process to assure the manufacturing area is decontaminated Greatly reduced false positives because products match the decontamination process A highly flexible portfolio of BI’s to match the resistance of process parameters Whether it be stainless steel discs/ribbons or a spore suspension, Apex® BI products offer the ideal solution to monitoring hydrogen peroxide decontamination, utilizing vaporized hydrogen peroxide (VH202) decontamination. Mesa Laboratories, Inc., Pharmaceutical Online #vaporhydrogenperoxide #sterilization #pharma #decontamination #pharma #qualityassurance Dan Johnson, Crystal Sgrignoli Hostler, Megan Wood

👉 HIGH-FLOW DUST COLLECTOR   SECTOR: pharmaceutical MATERIAL: pharmaceutical powders CUSTOMER: pharmaceutical company GOAL Suction of suspended dust from an open screen.   BENEFITS Confinement and containment of dust that may be dispersed into the environment during the screening process. The high-efficiency fan allows the capture of suspended dust with low energy consumption. The hood with containment strips confines the suction area without dispersion. The cartridges with continuous cleaning allow high filtering efficiency to be maintained, preventing clogging. The Longopac® packaging system allows the suctioned dust to be packaged while keeping it confined.

📕📊 Particle Size Analysis for the Pharmaceutical Industry ➡️ Download the free application report now: https://loom.ly/5GrXbAw When it comes to the shelf life of products in the pharmaceutical industry, particle size plays a huge role. It strongly relates to flowability, content uniformity, bioavailability, dissolution and absorption behavior, all of which are crucial parameters. Therefore, particle size distribution (PSD) is one of the most important parameters to check when evaluating new drugs. We put this to the test by measuring the PSD of different samples of lactose. Rick Vosloo, Preshnie Naidoo, Serena Christil Govender, Dr. Silindile (PhD Chemistry) (Pr.Sci.Nat.) (PDBA), Tjaart Willemse, Asiphe B Sobuwa #antonpaar #pharmaceuticalindustry #psd #particlesize #bioavailability #dissolution #absorption #applicationreport

Dimethicone, also known as polydimethylsiloxane (PDMS), is a silicone-based polymer that is extensively used in personal care products, pharmaceutical formulations, medical devices, foods and beverages, and many other industrial applications. In this application note, we demonstrate a quantitative analysis by #FTIR streamlined by an OMNIC Paradigm Workflow, using dimethicone as an example. Explore the full application note now. https://lnkd.in/gw6g3rMT #TFSCAD

Dimethicone, also known as polydimethylsiloxane (PDMS), is a silicone-based polymer that is extensively used in personal care products, pharmaceutical formulations, medical devices, foods and beverages, and many other industrial applications. In this application note, we demonstrate a quantitative analysis by #FTIR streamlined by an OMNIC Paradigm Workflow, using dimethicone as an example. Explore the full application note now. https://lnkd.in/gw6g3rMT #TFSCAD

From solvents to acids, Fluid Metering pumps help advance a broad spectrum of pharmaceutical applications. Their accuracy and precision have proved to be reliable in chemical mixing, dissolution dispensing, pulseless metering for tissue preparation, fermentation chemical feeds, and other types of research tests. Get a sample dose of our pharmaceutical system knowledge at https://hubs.la/Q02-dMpx0. #PharamaceuticalResearch #PharamaceuticalTesting #DissolutionTesting #PharamaceuticalManufacturing #DrugResearch #DrugAnalysis #DrugDiscovery #PharmaceuticalScience #PharmaInnovation #PharmaceuticalIndustry #PharmaIndustry

Expert Guide | USP <1660> Analytical Strategies: Pharmaceutical Glass Delamination Studies Glass remains the preferred option for parenteral or injectable drugs, yet its interaction with drug products necessitates thorough evaluation due to potential issues such as leaching, ion exchange, and delamination. In this guide, in accordance with USP <1660>, we discuss various test methods typically applied to evaluate the interaction of the DP (drug product) or a simulant solution with the glass container after normal or accelerated storage conditions at different time points. We will also cover DIC Microscopy and SEM investigation of the inner vial glass surface (SEM, DIC); Monitoring of elemental composition by ICP; Particle screening (PS), and more. Get your guide now and stay informed: https://lnkd.in/eha6yFKC #PharmaPackaging #USP1660 #DrugProduct #GlassDelamination #AnalyticalStrategies