Caliway Biopharmaceuticals’ Post

Aloe vera leaf is a plant used to treat multiple conditions associated with the skin. It has the ability to alleviate symptoms caused by eczema, various dermatitis conditions (radiation, atopic, contact, etc.), sunburn, and first- and second-degree burns. The polysaccharides contained in aloe have the ability to inhibit the formation of free radicals, protect cell membranes from peroxidative damage, decrease the breakdown of collagen in the early stages of cutaneous wound repair, promote bone formation, and inhibit apoptosis of cells in damaged skin. These polysaccharides are capable of downregulating anti-apoptotic factors, and upregulating pro-apoptotic factors. They are also capable of reacting with oxygen which prevents the formation of free radicals produced in Fenton reaction systems (Drugbank Online, 2017). References Drugbank Online. (2017). Aloe vera leaf. Go.drugbank.com. https://lnkd.in/eHiqmpdf

📢Game-Changing FDA Fast Track for Breakthrough Septic Shock Treatment! 🎯 German biotech Adrenomed AG has received fast track designation from the FDA for its septic shock therapy enibarcimab. 🩸 The treatment restores the integrity of the endothelium, leading to a reduction in mortality rates. 🚀 Adrenomed plans to begin a pivotal Phase IIb study to further validate the therapy's effectiveness. 💊 Enibarcimab acts like a hoover for the vasoactive peptide adrenomedullin, fixing it to the intravascular compartment and restoring endothelial function. 💡The therapy has the potential to become the first effective and targeted treatment for septic shock. #BioprocessUpdates #AdrenomedAG #FDA #fasttrackdesignation #septicshocktherapy #enibarcimab #endothelium #mortalityrates #PhaseIIbstudy #vasoactivepeptide #adrenomedullin #endothelialfunction #targetedtreatment #biotech #Germanbiotech #septicshock ▷ Read the full article here: 📎 https://lnkd.in/de3GnuMg

Older GLP-1 drug from Novo Nordisk may slow Alzheimer's disease progression by protecting the brain, study says A box of the drug Victoza, made by Novo Nordisk Pharmaceutical, sits on a counter at a pharmacy in Provo, Utah, January 9, 2020.George Frey | ReutersAn older, once-daily drug for diabetes and obesity from Novo Nordisk called liraglutide may slow the progression of Alzheimer's disease by protecting patients' brains, according to data from a mid-stage trial released on Tuesday. Novo Nordisk sells liraglutide as a diabetes and obesity drug under the brand names Victoza and Saxenda, respectively. ... Read more here: https://lnkd.in/dGuCcP3n . . Like 💝 Comment below ⏬ Share ✅ For More Such Updates Follow Us @qnewshub @qnewscrunch . . #qnewshub #qnewscrunch #Business

In this short case review, Dr. Ilana Gurevich dives into bile acid diarrhea and how the GI‑MAP® can uncover the root causes for personalized treatment plans. Discover the roles of primary and secondary bile acids, GI‑MAP markers like steatocrit, and how targeted treatments—both natural and pharmaceutical—can improve patient outcomes. Learn how to manage bile acid malabsorption effectively. . #GIMAP #guthealth #functionalmedicinedoctor #rootcausemedicine

Absorption, disposition, metabolic fate and elimination of the anti-epileptic drug lacosamide in humans: mass balance following intravenous and oral administration https://t.co/ki9n7vgT1C #EurekaMag

How Long Until Liver Enzymes Normalize After Stopping Lipitor? Introduction Lipitor, a popular cholesterol-lowering medication, has been linked to liver enzyme elevations in some patients. If you've experienced liver enzyme elevations while taking Lipitor, you may be wondering how long it takes for your liver enzymes to normalize after stopping the medication. In this article, we'll explore the answer... https://lnkd.in/e4gviRkF

#BeckleyPsytech announced that the #firstpatient has been treated in the second part of its two-year Phase IIa study evaluating #BPL003 in patients with treatment-resistant depression (TRD). The intranasal, patent-protected, synthetic, fast-acting benzoate salt formulation known as BPL-003 is Beckley Psytech's hot property in the #psychedelicmarket. Chemically based on 5-MeO-DMT (also known as mebufotenin), BPL-003 is synthetically manufactured and patent-protected and is being evaluated in the open-label Phase IIa study (NCT05660642) in patients with moderate to severe TRD who are on certain defined selective serotonin reuptake inhibitors (SSRIs). Single doses of BPL-003, along with psychological support, will be administered at selected and qualified study sites to evaluate the safety, tolerability, efficacy and pharmacokinetics of BPL. A really interesting approach and we wish them luck and success! https://lnkd.in/eP_wa22a

How Long Until Liver Enzymes Normalize After Stopping Lipitor? Introduction Lipitor, a popular cholesterol-lowering medication, has been linked to liver enzyme elevations in some patients. If you've experienced liver enzyme elevations while taking Lipitor, you may be wondering how long it takes for your liver enzymes to normalize after stopping the medication. In this article, we'll explore the answer... https://lnkd.in/evjhqvnn

🌟 Fighting Superbugs With rising multidrug resistance in Candida auris, identifying effective treatments is more critical than ever. In our latest work published in RSC Advances, we demonstrate how Dermaseptin targets oxidative stress enzymes in C. auris, inducing oxidative damage and apoptosis. This study highlights the potential of Dermaseptin as a promising lead for antifungal drug development. ➡️ https://lnkd.in/daatUQWS #AntifungalDiscovery #DrugResistance #CandidaAuris #Dermaseptin #HealthcareInnovation

Tirbanibulin ointment is used for the topical treatment of actinic keratoses (pictured). It is a synthetic inhibitor of tubulin polymerisation and protein kinase signalling. Areas of up to 25cm2 of affected sun-damaged skin have been studied on the face, scalp, and forearms, so it is suitable as a field therapy. The short duration of treatment (once daily for 5 days) is a potential advantage over some other self-delivered topical therapies for actinic keratoses. Have you started using this in your clinical practice yet, and has this been successful? Find out more about this ointment on our DermNet page here: https://lnkd.in/gWstPRGJ