Camila Pazos Maidana, Ph. D.’s Post

🎉 Exciting news! The 2024 Nobel Prize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for their pioneering discovery of microRNA (miRNA). This tiny but mighty molecule regulates gene expression by binding to specific mRNA sequences, affecting protein production and influencing cell development and disease mechanisms. This will transform our understanding of gene regulation and holds significant implications for cancer, genetic disorders, and more. 🌟🔬 #NobelPrize2024 #GeneRegulation #microRNA #ScienceNews

The 2024 Nobel Prize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation. By ensuring that only certain genes are activated in each cell type, miRNA regulate cellular differentiation, a process that is fundamental for the development and function of organisms. On the other hand, abnormal regulation by miRNA can lead to cancer or other diseases. More info in the article #NobelPrize #Medicine #Innovation #MedicalResearch #microRNA #Healthcare

Our PNAS paper is now out - CRISPR gene editing for C9orf72 FTD/ALS in patient iPSC-derived neurons. One step closer to CRISPR therapy for fatal genetic dementia and ALS. https://lnkd.in/gqVDERfM

🎉 Congratulations to Victor Ambros and Gary Ruvkun on their groundbreaking discovery of microRNA and its pivotal role in post-transcriptional gene regulation! and receiving the 2024 Nobel Prize in Physiology or Medicine🎉 This year's Nobel Prize honors their remarkable contribution to our understanding of how gene activity is controlled within cells. Their discovery of microRNAs—a class of tiny RNA molecules—has uncovered a completely new dimension of gene regulation, one that is essential for the development and function of multicellular organisms, including humans. MicroRNAs act as key regulators, ensuring that the right genes are active at the right time and in the right cell types. From muscle to nerve cells, this precise regulation is crucial for cellular function, adaptation, and health. Their work has paved the way for countless advancements in biology and medicine, revealing new insights into how diseases such as cancer, diabetes, and autoimmunity can arise when gene regulation goes awry. #NobelPrize2024 #gene #genes #genetic #rna #genetherapy #DNA #drugdiscovery #innovation #nobel

Remember the ice bucket challenge from 10 years ago? Day 8 of celebrating good news in cell and gene therapies: Broken String Biosciences announced a new research collaboration with The Francis Crick Institute to develop novel applications for ALS therapies. Leveraging Broken String's whole genome cell-based assay that can be used for measuring and quantifying DNA double-strand breaks, researchers will be conducting research to understand the role of genome stability in the underlying mechanisms of ALS disease progression, hopefully translating into new diagnostics and treatment approaches for ALS patients. Great to see collaborations in the field to advance research for unmet medical needs! https://lnkd.in/eVRMCN3J #CGT #celltherapies #genetherapies #geneediting #celebrate #monthofCGTcelebrations #ALS #collaboration

Explore the Power of miRNAs in Modern Science!🧬 MicroRNAs are key players in gene regulation and are driving cutting-edge research. MicroRNAs are key players in gene regulation and are driving cutting-edge research. In this blog, our Senior Scientist, Dr. Arivusudar Everad John, dives into 5 impactful applications of miRNA.  Click here for a technical deep dive!  🔗 https://bit.ly/4d4U15m #miRNA #GeneRegulation #Diagnostics #TranslationalMedicine #AutoimmuneDiseases #PlantGenomics #ResearchBlogs #Blogposts #ResearchInnovation #StrandLifeSciences

📢 New Insight in Gene Therapy Researchers at the RCCS San Raffaele Scientific Institute in Milan have discovered that hematopoietic stem cells (HSCs) adapt their lineage commitment in response to the specific genetic disease they’re treating. This means that during gene therapy, HSCs shift their development to better address disease-specific needs. This discovery offers promising directions for refining HSC-GT protocols and improving long-term patient outcomes. Exciting times ahead for #GeneTherapy and personalized medicine! #GeneTherapy #StemCells #Hematology #Biotechnology #MedicalResearch #HealthcareInnovation

Gene regulation: Controlling cells to improve medical treatments: Scientists revealed how gene regulation and chromatin control cells, improving disease treatments, including cancer and tissue regeneration. #Genes #GeneRegulation #MedicalTreatments #Chromatin #ChromatinControlCells #Cancer #TissueRegeneration #CancerTreatment #Genetics #EarthDotCom #EarthSnap #Earth

https://lnkd.in/dhs748nW 🎉 Exciting news for the medical community! This year's Nobel Prize in Medicine is awarded to Victor Ambros and Gary Ruvkum for the discovery of microRNA and its role in post-transcriptional gene regulation. 🔬Their discovery of microRNA has transformed our understanding of gene regulation, revealing how these small molecules control essential cellular processes. As someone with a background in researching the role of microRNAs in cancer and autoimmunity, I've seen firsthand how microRNAs dysregulation can drive disease progression by disrupting immune response and cellular balance. This Nobel prize underscores the potential of RNA therapies, that could restore balance in gene regulation offering hope for better treatments. 🌏 A huge leap forward in both basic science and clinical medicine!!