Cannabinoid Translational Science’s Post

🚨 Exciting news on this #FacultyFriday! We’re thrilled to welcome Dr. Arun Maji as the newest assistant professor in the Department of Pharmaceutical Sciences. With a strong background in organic synthesis, chemical biology, and drug discovery, Dr. Maji is set to drive groundbreaking research in antifungal therapies and translational science. 🌍💊 Dr. Maji’s work focuses on developing next-generation antifungal therapies to combat drug-resistant pathogens—an urgent global challenge. Invasive fungal infections pose a serious threat, especially to immunocompromised patients, and current treatments are often limited by toxicity or resistance. His innovative approach aims to create safer, more effective therapies that can offer rapid and long-lasting protection. This research could have a transformative impact on healthcare, addressing a critical need for better treatment options. We can’t wait to see the incredible advancements he'll bring to our community! 🔬🍄 READ: https://bit.ly/4dNPpCb #DrugDiscovery #HealthcareInnovation

🔬 Exciting news from Bio-Techne We've developed a new application note on optimizing organoid culture. Discover how the activity and consistency of growth and differentiation factors influence experimental outcomes. 🧬💡 Whether you're studying disease mechanisms, drug screening, or personalized medicine, our insights can help propel your research forward. 🚀 Dive into the world of organoid culture with Bio-Techne and unlock new possibilities in biomedical research! 🌟 #Biotechne #Organoids #Research #Innovation

🧫 Curious about organoids? 🧬 Our app note delves deep into the world of these tiny yet mighty structures, mimicking real organs in the lab. Uncover the importance of growth factors and reagent consistency in cultivating these mini marvels. Embark on a journey through human organ development, disease modeling, and beyond! Check it out: #MiniOrgans #Organoids #LabScience

We would like to congratulate Mrs. Kruti Naik, Prof. Lisa du Toit, Dr. Naseer Ally and Prof. Yahya Choonara from the Wits Advanced Drug Delivery Platform Research Unit at the University of the Witwatersrand (Johannesburg, #SouthAfrica) for their new article published in the journal of Drug Delivery and Translational Research. The group developed a thermoresponsive, nano-enabled hydrogel for retinal disease treatment, made from hyaluronic acid, poloxamer, and TA-encapsulating nanoparticles. The hydrogel, confirming physicochemical stability and efficient nanoparticle integration, gelled within 9-10 minutes and showed similar viscoelasticity to natural vitreous. It enabled sustained drug release over nine weeks, demonstrated minimal swelling, biodegradation, and biocompatibility. Preliminary in vivo studies suggested low toxicity and effective, localized drug delivery, indicating potential for post-vitrectomy applications. Access the full article here: https://lnkd.in/eAZx3FYn Discover the wide range of applications of the the #ElastoSensBio here: https://lnkd.in/ewCyicsA #RetinalDisease #NanoEnabledHydrogel #DrugDeliverySystems #SustainedRelease #ThermoresponsiveHydrogel #InnovativeHealthcare #BiomedicalEngineering #VitrectomyRecovery #EyeCareSolutions #MedicalResearch #NanotechnologyInMedicine #Hydrogels

#callforpapers 🎯 We are happy to inform you that Targets MDPI has announced a new #specialissue ! ✨ "Comprehending Molecular Targets: Mechanisms and Actions in Drug Development" 💻 Website: https://lnkd.in/dpWD_KzF ⏰ Submission Deadline: 31 December 2024 🤼 Guest Editors: Dr. Cristina Manuela Drăgoi Dr. Ion-Bogdan Dumitrescu 📑 Submission link: https://lnkd.in/dWwXJ4G6 In this Special Issue, we aim to explore the diverse landscape of #drug #targets across different #therapeutic areas. We invite researchers, scientists, and clinicians to contribute original research articles, reviews, and perspectives that will advance our understanding of drugs’ targets. Looking forward to receiving your valuable work! Carol Davila University of Medicine and Pharmacy #openaccess #therapeutictargets #drugdesign #targetdiscovery #noveltherapeutics #chronobiology #medicinalchemistry #personalizedmedicine #biomoleculartargets #molecularpharmacology #targetidentification

📢 A new Special Issue "Bioengineering Platforms for Drug Delivery" is now open for submissions! 🥼 This Special Issue is guest-edited by Dr. Anam Ahsan. 💡 Drug delivery is a progressive field in contemporary medicine that has improved clinical relevance and brought new hope for the treatment of intractable diseases. Recent advances in nanotechnology and bioengineering are dedicated to overcoming current limitations, such as key challenges of systemic toxicity and physiological barriers, providing the ability to precisely target, regulate drug release, and achieve synergistic drug co-loading. 🔗 Click the link to access more details about the Special Issue: https://lnkd.in/gf8ViUxC. 🕑 The deadline for manuscript submissions is 25 March 2025. 🎉 Welcome to join us as authors and reviewers! 👏 And welcome to follow our LinkedIn account: https://lnkd.in/grPNkBrg. #biomaterials #drug_delivery #nanotechnology #nanobiotechnology #bioengineering #chemotherapy #bioconjugation #disease_management #therapeutic #agents

https://lnkd.in/g6CQcWZF Abstract The #gut #microbiome harbors trillions of organisms that contribute to human health and disease. These #bacteria can also affect the properties of medical #drugs used to treat these diseases, and drugs, in turn, can reshape the microbiome. Research addressing interdependent microbiome-host-drug interactions thus has broad impact. In this Review, we discuss these interactions from the perspective of drug bioavailability, absorption, metabolism, excretion, toxicity, and drug-mediated microbiome modulation. We survey approaches that aim to uncover the mechanisms underlying these effects and opportunities to translate this knowledge into new strategies to improve the development, administration, and monitoring of medical drugs.

🧬 Unlocking the Potential of Small Molecules in Medicine 🧬 Why are small molecules a cornerstone in therapeutic development? Join Dr. Kishore V Renduchintala, Executive VP and Head of Discovery Sciences at LAXAI Life Sciences, at our Drug Discovery & Development Workshop as he unpacks the power and potential of small molecules to treat complex diseases. From design to synthesis, learn how advances in medicinal chemistry are leading to more effective and safer drug therapies. Kishore's session will cover: - Latest techniques in lead optimization - Challenges in drug design for targeted therapies - Case studies on breakthrough small molecule drugs 🌐 Dr. Renduchintala brings over two decades of experience and will share insights into how small molecules are designed, optimized, and developed into life-saving treatments. 📅 Event Date: 3-16 August, 2024 👉 Register Here: https://lnkd.in/ekGgYQkZ #MedicinalChemistry #DrugDesign #DDD2024

#Health | 𝗖𝗮𝘂𝘀𝗲 𝗼𝗳 𝗖𝗹𝗼𝗴𝗴𝗲𝗱 𝗛𝘆𝗽𝗼𝗱𝗲𝗿𝗺𝗶𝗰 𝗡𝗲𝗲𝗱𝗹𝗲𝘀 𝗗𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝗲𝗱 | The team of researchers led by Dr. Vladimir Novak has put forward new techniques to understand and prevent blockages in prefilled syringes. This study was also made possible by the PSI Paul Scherrer Institut and ANAXAM - Technology transfer center for advanced manufacturing, in collaboration with MSD, Dr. Margie Olbinado, Dr. David Mannes, and Dr. Christian Grünzweig. The research took an in-depth look at needles using neutron and synchrotron imaging. They deciphered potential blockage causes and set conditions to prevent future occurrences. This work is crucial considering the possible serious implications of blocked syringes for patients - impeded medication entry or insufficient dosages. The insights this study offers can enhance pre-filled syringes' safety and reliability for pharmaceutical companies and healthcare professionals. 👉 Learn more >> https://lnkd.in/gDXky7XB 👉 Original publication >> https://lnkd.in/geZU6q8b 🇨🇭 Follow #ScienceSwitzerland for the latest news and emerging trends on Swiss science, technology, education, and innovation >> www.swissinnovation.org Follow us >> Science-Switzerland #Science | #Education | #Research | #Innovation

#Journal_Club Session 6 The Journal Club will be held on Tuesday February 8, 2022, from 7:00 PM to 8:00 PM. In this session, we will discuss the article titled: "An Updated Review of Computer-Aided Drug Design and Its Application to COVID-19" Lecturer: Dr. Elaheh Kashani-Amin (https://lnkd.in/gH_tXDf7) PhD, Molecular Medicine, Protein Molecular Modeling and Computer-aided Drug Design These are the highlights of this review article: 1) Structure-Based Drug Design:  - Molecular docking tools for protein-ligand interaction studies - A summary of commonly used molecular dynamic (MD) simulation software 2) Ligand-Based Drug Design - A list of pharmacophore modelling tools - List of programs available for calculating molecular descriptors for building QSAR models 3) Case Study of COVID-19 4) Strengths and Challenges of CADD in COVID-19 Research The sessions are free of charge. To register and receive the group link, please contact us via email: Email: elahehkashaniamin@gmail.com Social Media Links: - Telegram: @molecular_modeling - Instagram: @go_molecular_modeling #drugdesign #computationaldesign #molecularmodeling #computationaldesign #drugdiscovery #drugdevelopment #pharmacophore #covid19 #CADD