Celiac Disease Foundation’s Post

🚨 Echinocytes in Cats: Causes and Diagnosis 🐾 Recently, I came across a case with echinocytes (burr cells) present in a cat’s blood smear. Echinocytes, which appear as red blood cells with spiky projections, can signal various underlying conditions. Here's a quick breakdown of the common causes and diagnostic approach: Common Causes: 1. Dehydrationor Electrolyte Imbalances (like low potassium) 2. Toxin Exposure (e.g., snake bites, drugs, or chemicals) 3. Chronic Kidney Disease (CKD) leading to uremia 4. Liver Disease 5. Blood Sample Artifacts from poor handling or prolonged EDTA exposure Diagnostic Approach: - Blood Smear Examination for burr cell identification - CBC & Electrolyte Panels to detect imbalances or dehydration - Kidney and Liver Function Tests to identify organ-related causes - Toxin Screening if ingestion or envenomation is suspected Early detection of echinocytes helps uncover serious underlying health issues, allowing for timely intervention. #VeterinaryMedicine #FelineHealth #Echinocytes #DiagnosticMedicine #ExoticAnimalCare #KidneyDiseaseInCats #CatCare

We are excited to announce our latest partnership with n-Lorem Foundation to develop personalized antisense oligonucleotide (ASO) treatments for patients with ultra-rare and nano-rare diseases. In many cases, nano-rare patients will succumb to their disease without ever having hope of a treatment that will halt their progressive diseases. But working with n-Lorem, we hope to change this. We will provide amidites, compounds essential to developing ASO medicines, to n-Lorem to help offset the costs of developing ASO medicines for up to 20 nano-rare patients. Learn more from Wei Jiang and Stanley Crooke about this exciting partnership below. 👇 https://loom.ly/zDaQhRk #RareDiseases #DrugDevelopment #Oligonucleotides

In this #article with The Medicine Maker, Dr. Asma Patel, VP of Integrated Development Services, discusses how accelerating first-in-human #clinicaltrials is crucial in #drugdevelopment, especially for orphan drugs treating rare diseases: https://lnkd.in/eqV3kKhm

Mark Kotter shares his insights on the translation gap in drug development and the importance of using human cells from the onset to overcome the challenges of treating human diseases 🚀💡 #TranslationGap #StemCellBiology #TheBiotechStartupsPodcast

Infectious Diseases Society of America issued guidelines for Management of multi-drug resistant gram negative organisms. Do give a read to it and rationalise the antimicrobials therapy. #antimicrobial #antibiotics #microorganism #infectiousdisease #resistance #antimicrobialresistance #antimicrobialstewardship #bacteria #pharmacist #clinicalpharmacist #doctors #physicians #Clinicians #pharmacy #drugs #therapy #mdr

A randomized trial of 2,760 critically ill adults with suspected sepsis found that a procalcitonin (PCT)- guided protocol reduced antibiotic duration and was non-inferior in mortality compared to standard care. A C-reactive protein (CRP)- guided protocol showed no benefit in antibiotic duration and inconclusive mortality results. #sepsis #antibiotics #procalcitonin #biomarker

500 million years of evolution... now helping us treat diseases? Worms might be the most surprising heroes in autoimmune treatment. Here's why... It sounds wild, but Andrea Choe, CEO of Holoclara Inc, shares the story that led her to work on worm-based medicine. She heard on a podcast about a man who walked barefoot in Africa to get worms to treat his illness... and it worked! Andrea also talks about the moment she first saw the dataset. It showed signs of how worms have been "talking" for millions of years. Today, Holoclara is the first biotechnology company to develop worm-based treatments. We're talking discovery of molecules derived from these worms. Which then could help with diseases like Crohn’s disease and allergies. Crazy, right? 🎥 Watch the full episode here: https://lnkd.in/ejsEEBcf

Great job Quinn Kolar! Her research on mastitis treatment and prevention can be read here: https://lnkd.in/edKVUY2g 2 takeaways for me: more than half of #mastitis cases spontaneously cure and primiparous cows have bacteriological cure more often than multiparous cows.

Our new multicentric paper on biological phenotyping in Inflammatory Bowel Diseases Sci Rep, 2025 vol. 15(1) p. 2135 Urinary prostaglandin metabolites evaluation for activity monitoring in inflammatory bowel disease https://lnkd.in/ed9SuMtY

Antimicrobial resistance is one of the biggest global health challenges of our time. Here is a powerful opportunity for us to take action! 🛡️Backbone of Modern Medicine: Antimicrobials enable us to perform surgery, give patients chemotherapy, and treat dangerous infectious diseases such as tuberculosis, sepsis, and meningitis. 🔬Antimicrobial Resistance (AMR): Over time, microbes develop resistance, rendering treatments ineffective, posing a grave threat to global health. AMR causes over 2.8 million infections, 35,000 deaths and 55 billion dollars in economic losses each year in the US alone. 💰Market Challenges: Current market incentives fail to stimulate new drug development, leaving us vulnerable to resistant infections. 🔑PASTEUR Act: A bipartisan solution gaining momentum in Congress, promising manufacturers a guaranteed revenues to incentivize antimicrobial R&D. An analysis from the Center for Global Development estimated that over a 30-year time horizon, this policy could save over 383,000 lives in the US alone and have an return on investment of almost 28:1. 📝 Take Action: Join the fight against AMR by encouraging your representative to sign a letter supporting the PASTEUR Act by using this online action alert provided by IDSA: https://lnkd.in/gftHj7Ea Together, let's tackle AMR and safeguard the effectiveness of antimicrobials for future generations! #AMR #PASTEURAct