CERA researchers have successfully used an innovative gene therapy technique that could one day replace the need for regular eye injections for conditions including ‘wet’ age-related macular degeneration and diabetic eye disease. Their technique edits a person's RNA, which changes the genetic instructions that influence the way cells behave without permanently altering DNA. "We envision that RNA editing could become a viable alternative to invasive and costly eye injections that have become a fact of life for many people," says Head of Genetic Engineering Research Associate Professor Guei-Sheung (Rick) Liu. Read more: https://ow.ly/7n6350U2O0q
Centre for Eye Research Australia (CERA)’s Post
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Large-volume transfection can be a relevant tool throughout the whole cell and gene therapy pipeline, be it during earlier research, pre-clinical phases or for the manufacture of an ATMP. In this white paper we aim to provide insights into our customers’ work and how the electroporation-based Nucleofector® Technology supports them in research or clinical phases. Download the white paper and read about the genetic engineering pathways used by your peers including: - Base editing - CRISPR-based knock-out - Virus production Download here: https://lnkd.in/efi84DuB #genetherapy #electroporation #nucleofection
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Looking for some summer learning? Check out Thermo Fisher's Basic Gene Therapy Education Series! Gene therapy provides a promising way to treat inherited and acquired diseases via transfer of genetic material. In this knowledge culture basic education series on lentiviral vectors, delve into principles of lentiviral transduction and challenges in suspension-based lentivirus production as well as lentiviral vector purification and associated analytics.
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Redefining Gene Therapy: CRISPR’s Genome Editing: This groundbreaking technique, which involves replacing entire coding sequences or exons while retaining critical regulatory elements, holds promise for treating various genetic disorders. https://lnkd.in/dQiazcsU
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Ever wondered about the powerhouse driving gene-editing breakthroughs? It's CRISPR-Cas9, a revolutionary technology that's transforming medicine. 🧬 CRISPR-Cas9 acts like molecular scissors, precisely snipping DNA to correct genetic defects or insert beneficial genes. This paves the way for potential cures to a myriad of genetic disorders. The recent study published in Scientific Reports demonstrates a leap in gene therapy using CRISPR-Cas9 and CRISPR-Cas12a, enabling safer and more precise in vivo gene targeting. Read here:https://lnkd.in/gt7CzZAS #Tsingke #TsingkeInsights #GeneEditing #CRISPRCas9
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Gene therapies are key to advancing innovative treatments for conditions with unmet needs. Dr. Marks and Dr. Miller discuss the various types of gene therapy currently in play and where AI could be at it’s best in this space in this episode of Science With a Twist.
[Video] Thermo Fisher Scientific on LinkedIn: Science With a Twist – It’s In Our Genes: The Potential of Gene Therapy…
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Unlocking gene regulation with sequence-to-function model https://lnkd.in/ds3nUwph
Unlocking gene regulation with sequence-to-function models - Nature Methods
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Mutations in Bestrophin gene cause a genetic blindness that can be reversed with gene therapy. Translation to human clinical trials is currently in planning stages by Opus Genetics. We used ultra-high resolution OCT imaging to re-evaluate a primary and unusual feature: formation of micro-detachment between photoreceptors and the RPE layers following light exposure. Thanks to first author Vivian Wu, and collaborators Malgorzata Swider, Alexander Sumaroka, Valerie Dufour, Joe Vance, Tomas Aleman, MD, Gustavo Aguirre, and William Beltran. https://lnkd.in/epW7Auqy
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On RNA Day, CoJourney spotlights the vital role RNA plays in gene therapy and the groundbreaking research at CoJourney. RNA isn’t just a molecule—it’s a key to unlocking new treatments and advancing personalized medicine. Today, we celebrate the science that propels us forward and the potential RNA holds for transforming lives. Here’s to the future of genetic innovation! #RNADay #GeneTherapy #ScientificBreakthroughs #PersonalizedMedicine #HealthInnovation #RNA #GeneticAdvancements #GeneticResearch #FutureOfMedicine #CoJourney
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Gene therapies are key to advancing innovative treatments for conditions with unmet needs. Dr. Marks and Dr. Miller discuss the various types of gene therapy currently in play and where AI could be at its best in this space in this episode of Science With a Twist.
[Video] Thermo Fisher Scientific on LinkedIn: Science With a Twist – It’s In Our Genes: The Potential of Gene Therapy…
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🚀🔬 Dive into the future of gene therapy with our latest blog post on viral vector gene therapy! Discover how viruses are transformed into powerful tools for genetic innovation. Learn about the cutting-edge techniques and solutions from Gibco that are revolutionizing the field. Don't miss out on this essential read! 🌟✨ #GeneTherapy #CellBiology #BiotechInnovation #ViralVectors #Gibco Read more: https://lnkd.in/ggscXy-j
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