Christine Curcio’s Post

✨ 8th Publication in 2024! ✨ Proud to have contributed as an author to the paper titled "High-Resolution Optical Imaging Incorporated Non-Destructive Morphological Boundary Detection of Fruit Disorders: Pilot Study," which was presented at ICAC 2024! #Research #Publication #GoldenYear

Ever wondered how #cardiac tissue behaves at the myofibrillar level? With the #AuroraScientific 1700A Myofibril Test System researchers are able to investigate and measure the nano Newton forces present following activation of a single #myofibril. Learn more about the Myofibril Test System: https://ow.ly/s3Bg50SEeba Dilson Rassier’s group published a paper, where they were able to observe a potential compensatory mechanism by the diaphragm in a chronic heart failure mouse model. Read the paper: https://ow.ly/mSlw50SEeb9

Multi-center study on all MICCAI and ISBI 2021 (n = 80) challenges investigating winning solution characteristics and common participation strategies! Eisenmann et al. (2023). Why is the winner the best? CVPR 2023. [url]  Eisenmann et al. (2022). Biomedical image analysis competitions: The state of current participation practice. arXiv:2212.08568.

🎵 The 12 Days of LabAnimal 🎵 Day 4: On the fourth day of research, a new need came to be, An in vivo modeling of postpartum hemorrhage, urgently. Issue 👇 https://lnkd.in/egddmEkd Full study link 👇 https://lnkd.in/eGzGxErA

Check out this recently published methods article from Dietmar W. Hutmacher from Max Planck Queensland Centre (MPQC) on the line between in vitro and ex vivo investigations! In tissue engineering research, the terms in vitro, ex vivo, and in vivo are essential but often misunderstood. In vitro means "in glass," referring to lab experiments in test tubes, while in vivo involves living organisms, and ex vivo pertains to living tissue outside its host but in controlled conditions. As experimental models become more complex, the distinction between in vitro and ex vivo can blur, leading to confusion. This discussion aims to clarify these terms and establish criteria for ex vivo experiments, helping the tissue engineering and regenerative medicine community enhance their understanding and communication. Read more here: https://lnkd.in/erPpNatT

It's #ACS_NCW, and this year's theme, "Picture Perfect Chemistry," inspires us to showcase the beauty and precision of scientific discovery. Using the Promega Lumit® Immunoassay and the GloMax® Galaxy Bioluminescence Imager, we captured these stunning images of HeLa cells treated with SJ6986, a GSPT1 degrader. By combining advanced cellular assays with powerful imaging, we’re helping researchers reveal new insights with clarity and confidence. Explore how these tools are accelerating breakthroughs in biochemistry: GloMax® Galaxy Bioluminescence Imager https://bit.ly/3NAHXP1 Lumit® Cellular Systems Immunoassay https://bit.ly/48hdChY #PicturePerfectChemistry #ScientificDiscovery #Promega

🌟Dive into the heart of #EIBIR with our Scientific Director, Prof. Regina Beets-Tan, MD, PhD! 🎬 Watch as she shares our mission, goals, and vision for the future in this insightful video. Discover how we're shaping the future of biomedical imaging together 🤝

🔬 Excited to share the new publication "Microfluidic-Based Novel Optical Quantification of Red Blood Cell Concentration in Blood Flow". 🥼 Authored by Yudong Wang, Bharath Babu Nunna, Niladri Talukder, and Eon Soo Lee. 🚀 The optical quantification of hematocrit (volumetric percentage of red blood cells) in blood flow in microfluidic systems provides enormous help in designing microfluidic biosensing platforms with enhanced sensitivity. By measuring the average grayscale of the images of blood flow at different luminous exposures, a relationship between hematocrit and grayscale has been developed. The experimental results obtained strongly supported the proposed optical technique of hematocrit measurement in microfluidic systems. Welcome to access the full article freely here 👉 https://lnkd.in/gD47fFNC. And welcome to follow our LinkedIn account: https://lnkd.in/grPNkBrg. 👏 #microfluidics #biosensing #hematocrit #optical #grayscale

Our new paper entitled 3D atlas of the human fetal chondrocranium in the middle trimester and published in Scientific Data (by Springer Nature Group) is finally online. In this work advanced microCT scanning was used that includes contrast enhancement to generate the first 3D atlas of the human fetal chondrocranium during the middle trimester (13 to 19 weeks). In addition, since cartilage and bone are both visible with the techniques used, the endochondral ossification of cranial base was mapped since this region is so critical for brain and jaw growth. Thanks for all our partners from a wide international team: Joy Richman and Siddharth Vora from The University of British Columbia, Brian Metscher from Universität Wien | University of Vienna and Igor Adameyko from Karolinska Institutet for pursuing this work. Big thanks goes also to Markéta Tesařová, from CTLAB CEITEC of CEITEC - Central European Institute of Technology, who was responsible for microCT scanning, segmentation, creating Figures and writing of the original draft and to Tomas Zikmund for guidance in microCT methodology. The article is Open Access and it is available here: https://lnkd.in/evqZrNcj #CEITECScience #ctlab #3D #atlas #chondrocranium #CT #micro

Universal tool for tracking immune cell interactions in vivo A new paper in Nature describes uLIPSTIC, a tool capable of laying the groundwork for a dynamic map tracking the physical interactions between different cells—the elusive cellular interactome. The authors have been perfecting the technology since 2018 and the latest iteration can in principle allow researchers to directly observe any cell-to-cell interaction in vivo. "With uLIPSTIC we can ask how cells work together, how they communicate, and what messages they transfer," says the senior author. "That's where biology resides." LIPSTIC, an innovative approach from the lab that involved labeling cellular structures that touch when two cells make fleeting, "kiss-and-run" contact before parting ways. The labels ensured that, if one cell "kissed" another, it would leave a mark akin to a lipstick, enabling easy identification and quantification of physical interactions between cells. #ScienceMission #sciencenewshighlights https://lnkd.in/dMMaF5WP