Circular Genomics’ Post

🔬 The Power of Biomarker Testing in Advancing Health 🔬 As we navigate the complexities of modern healthcare, biomarker testing is a pivotal tool in our mission to improve patient outcomes and advance personalized medicine. At the Cholangiocarcinoma Foundation, we believe in this technology's transformative potential. Biomarker testing enables tailored treatment plans, leading to better health outcomes for our community. It's not just about identifying diseases—it's about understanding them at a molecular level to provide the most effective care possible. #Cholangiocarcinoma survivor Matt Reidy shares his story about how biomarker testing changed his course of treatment after he found out he had the MLH1 mutation. There is hope in research. Matt's story: https://lnkd.in/gAPm9k8f #HealthcareInnovation #BiomarkerTesting #PrecisionMedicine #BiomarkersMatter #CureCCA #CCAHope

Blood biomarkers are changing the way physicians diagnose, manage and monitor multiple sclerosis (MS). The new Multiple Sclerosis Monitoring Profile combines two powerful biomarkers, NfL and GFAP, to help providers develop precise management strategies for MS, paving the way for more impactful care. This profile adds to our extensive MS portfolio, which spans the patient journey. Read more: http://spr.ly/6041QecMV #MultipleSclerosis #Biomarkers

A call for precision and objectivity in clinical care, particularly in biomarker discovery and recovery for active and aging patient populations. Too often, we capture patient-specific data only after significant functional deterioration. Without prior baseline measures or benchmark data, this information lacks the necessary impact. Every clinical setting, both traditional and digital, should prioritize objective measures and have the tools to consistently collect stable biomarkers, such as grip strength and gait, to improve patient outcomes. #ClinicalCare #Biomarkers #PatientOutcomes #DigitalHealth #ObjectiveData #HealthcareInnovation #AgingPopulation #PrecisionMedicine

#NewVideo🎥 Diving into the world of medical research, this video explores the crucial role of biomarkers in clinical trials. Biomarkers, or biological markers, are measurable indicators of a biological condition, providing signposts within our body that can help diagnose diseases, predict disease progression, and gauge treatment efficacy. From aiding in the discovery of new treatments to paving the way for personalized medicine, biomarkers stand at the forefront of innovative healthcare solutions. Watch the complete video here: https://zurl.co/bHXg #BiomarkersInClinical Trials #ClinicalResearch #HealthInnovation #MedicalResearch #ClinicalTrials

Combining multi-omics data with individualized clinical patient data allows for a more comprehensive understanding of disease mechanisms and personalized treatment strategies. This integrative approach can lead to more precise diagnoses and targeted therapies tailored to each patient's unique biological profile. #molecularmedicine #moleculardiagnostics #moleculartesting #multiomics #omics #personalizedmedicine #precisionmedicine

A recent study by AbbVie released in conjunction with the 2024 ASCO Annual Meeting used ConcertAI Patient360™ US dataset to assess biomarker testing disparities and their impact on overall survival. Results revealed disparities in testing rates and outcomes, particularly among different racial groups and treatment settings. Normalizing testing across race and treatment setting could potentially improve patient outcomes. More research is needed to confirm the impact of lack of biomarker testing on patient outcomes. Read the full study: https://hubs.ly/Q02BpfYV0 #LungCancerResearch #BiomarkerTesting #PatientOutcomes #HealthDisparities

Granger Genetics’ Asparaginase Panel Assay helps physicians make informed decisions about treatment by detecting antibodies that may impact therapy. This valuable tool supports clinicians in evaluating the presence of antibodies and determining the best path forward for their patients. #AsparaginaseTesting #BloodCancerAwareness #GrangerGenetics

The shift from a "one-size-fits-all" approach to Personalized Medicine is transforming patient care. Our latest article from AnaMaria-Corina Afuza, Account Executive explores how genetic profiles and biomarkers guide prevention, diagnosis, and treatment. Key insights include: 🔬 The role of biomarkers in health. 🌍 Applications across various therapeutic areas. ⚖️ Challenges we face in this journey. 📈 Advances in clinical trial design. Read the full article here: https://lnkd.in/gfUX2445. #PersonalizedMedicine #Biomarkers #HealthcareInnovation #PrecisionMedicine #ClinicalTrials

Just Released: The EANO Guideline on molecular testing of meningiomas for targeted therapy selection! Evidence-based guidance for patient care & clinical trials, and show of areas for which additional research is warranted. Learn more: https://lnkd.in/e7NgkWM2 #EANO #EANOguideline #Meningioma #TargetedTherapy #ICOM

📑 EANO European Association of Neuro-Oncology Guideline on molecular testing for Meningiomas for targeted therapy selection. 🧬 Meningiomas can express a wide range of molecular alterations and markers including  NF2, AKT1, SMO, SMARCE1, PIK3CA, CDKN2A/B, CDK4/6, TERT, TRAF7, BAP1, KLF4, ARID1/2, SUFU, PD-L1, SSTR2A, PR/ER, mTOR, VEGFR, PDGFR, as well as homologous recombination deficiency (HRD), genomic copy number variations, DNA methylation classes and combined gene expression profiles. 🎯 Based on the established ESMO ESCAT (European Society for Medical Oncology Scale for Clinical Actionability of molecular Targets) evidence level criteria, unfortunately, no molecular target reached ESCAT I (“ready for clinical use”) classification and only mTOR pathway activation and NF2 alterations reached ESCAT II (“investigational”) classification, respectively. 💡 This highlights the need for future research and innovative trial design that incorporates molecular profiling that allows for the evaluation of targeted therapy in these tumors. #neuronc #medonc #meningiomas #eano #targeted #therapy #molecular #profiling #personalized #medicine