🧠 Alzheimer’s Diagnosis, Simplified 🩸 Blood tests for biomarkers like amyloid beta and p-Tau are set to revolutionize Alzheimer’s diagnosis—less invasive, faster, and more accessible. 💡 Labs, get ready: 1️⃣ Assess your biomarker testing capabilities. 2️⃣ Optimize workflows for scalability. 3️⃣ Stay updated on emerging research. 🚀 The future of Alzheimer’s diagnostics is here—will your lab keep up? 👉 Learn more:https://buff.ly/3VEJ05c #Alzheimers #BloodTesting #LabInnovation #HealthcareAdvances #BeckmanCoulter
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Alzheimer’s disease has been traditionally difficult to diagnose. But the advent of blood-based testing for the disease has been a game changer. In this article,Arindam Ghosh explains how to get your lab ready for blood-based Alzheimer’s testing. Check it out!
🧠 Alzheimer’s Diagnosis, Simplified 🩸 Blood tests for biomarkers like amyloid beta and p-Tau are set to revolutionize Alzheimer’s diagnosis—less invasive, faster, and more accessible. 💡 Labs, get ready: 1️⃣ Assess your biomarker testing capabilities. 2️⃣ Optimize workflows for scalability. 3️⃣ Stay updated on emerging research. 🚀 The future of Alzheimer’s diagnostics is here—will your lab keep up? 👉 Learn more:https://buff.ly/3VEJ05c #Alzheimers #BloodTesting #LabInnovation #HealthcareAdvances #BeckmanCoulter
Preparing Your Lab for Blood-Based Alzheimer’s Disease Testing
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BE PIONEERING: The benefits of unlocking the value of diagnostic innovation in Alzheimer’s [Promoted content]: There is an urgent need to improve access to new innovations in the diagnosis and treatment of Alzheimer's disease. Embracing breakthroughs such as blood-based biomarker testing, has the potential to transform timely, accurate diagnosis for the benefit of patients and healthcare systems.
BE PIONEERING: The benefits of unlocking the value of diagnostic innovation in Alzheimer’s
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Phase 2A Proof-of-Concept Double-Blind, Randomized, Placebo-Controlled Trial of Nicotinamide in Early Alzheimer Disease Phase 2A Trial of Nicotinamide for Early Alzheimer Disease Study Overview This study tested nicotinamide, a coenzyme that may help reduce tau phosphorylation in early Alzheimer Disease (AD). Trial Details Type: Double-blind, randomized, placebo-controlled Duration: 48 weeks Dose: 1,500 mg of nicotinamide, taken twice daily Participants 47 participants were enrolled, aged around 74 years, with mild cognitive impairment or mild dementia confirmed by CSF biomarkers. Primary Outcome The main goal was to measure changes in tau levels in cerebrospinal fluid (CSF) after 48 weeks. Results showed: No significant difference in tau levels between the nicotinamide and placebo groups. Some improvements in tau levels were observed in the nicotinamide group, but not statistically significant. Secondary Outcomes Other measures included various CSF biomarkers and clinical assessments. Key findings included: No significant changes in secondary biomarkers. Participants on nicotinamide showed less decline in clinical assessments. Safety Nicotinamide was generally safe, with few adverse events reported. Common issues included infections and nervous system disorders. Conclusion This study indicates that while nicotinamide is safe, it does not effectively reduce tau levels in patients with early Alzheimer Disease. Practical Solutions and Value Clinical trials are essential for developing effective treatments. Our AI-driven platform, DocSym, aids clinicians by: Consolidating clinical standards and research into one accessible resource. Streamlining operations with mobile apps for scheduling and telemedicine. Improving workflows and patient outcomes while reducing paperwork. Learn more about our solutions at aidevmd.com. https://lnkd.in/g9YWUK6W #ClinicalTrials #AIinHealthcare #MedicalAI #HealthTech #DigitalHealth #PatientCareAI #AIResearch #MedicalInnovation #BioTech #AIforGood #HealthcareData #AIinMedicine #PharmaAI #ClinicalData #HealthAI #AIHealthSolutions #PrecisionMedicine #AIandHealth #ClinicalAnalytics #AIDiagnostics
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Reflecting on the enlightening discussions at #ADPD24 in #Lisbon, we're reminded of the vital importance of detecting Alzheimer's biomarkers for early intervention and tailored treatment plans. At our lab, we're dedicated to providing accurate and timely diagnostic tests. Proudly, we offer an extended analysis approach to detect Alzheimer's biomarkers comprehensively. Our panel includes pTau-181, Neurogranin and ApoE4 genotyping. Learn more about our new panel: https://hubs.ly/Q02pBY6d0. In our commitment to support Alzheimer's diagnosis, we strive to be a crucial puzzle piece, reach out to discuss your testing needs today! #AlzheimersDisease #Biomarkers #WieslabDiagnostics #Healthcare #BrainAwarenessWeek
Alzheimer's Disease Biomarkers – Extended Analysis
svarlifescience.com
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Are you investigating APOE4 in your Alzheimer's Disease projects? We can help! APOE4 has emerged as a high-risk allele for sporadic AD (sAD) which makes up the majority of AD cases. In this article, we explore the link between APOE4 and sAD and look at the role of APOE4 in advanced in vitro AD models powered by human iPSCs. We also discuss how we're helping researchers to unlock iPSC technology for APOE4 AD models with patient-derived iPSCs (including an APOE4 homozygous donor) and ‘made-to-order’ production runs using iPSCs from our axoLines™ range or your lines. Click here to read the article: https://hubs.la/Q02zDjt60 Get in touch with us at operations@axolbio.com to discuss your research needs. #iPSCs #AlzheimersDisease #APOE4 #StemCells #biopharma
Exploring APOE4 in iPSC-based Alzheimer's Disease models
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Today marks a significant milestone, after a long journey from high throughput biomarker screening, assay development, clinical evaluations with COPD users we are proud to share with you the outcomes from our study published in ERJ open access. Our product in development – Headstart has shown to be able to predict an exacerbation 1 week in advance. We used an artificial neural network to look for changes in the levels of five biomarkers in urine to predict when a patient might experience a flare up in COPD symptoms. Further trials are required to validate the test and demonstrate cost-effectiveness and improved health outcomes. Learn more: https://lnkd.in/dRiwSYEf Link to press release: https://lnkd.in/e_sW63cP Link to paper: https://lnkd.in/eAah8PWS #worldcopdday #GADx #HealthcareInnovation #diagnostics #COPD
World COPD Day: Introducing Headstart, a diagnostic test in development that can predict a COPD exacerbation 1 week in advance
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Don't miss our next webinar! Clario's experts will explore the critical aspects of conducting clinical trials in Alzheimer’s disease (AD). Topics will focus on: - The role of imaging biomarkers in characterizing patient eligibility, ensuring safety and evaluating therapeutic efficacy - Challenges associated with collecting endpoints for clinical outcome assessments in a changing patient population - Leveraging gait and balance measures for detection and diagnosis of cognitive impairment and dementia and their significance in early intervention -The complexities of running trials in populations at high risk for cardiovascular (CV) disease, emphasizing the importance of baseline testing regardless of the drug being investigated Register now to gain invaluable insights into Alzheimer's disease research: https://lnkd.in/e9FZwuGs #AlzheimersResearch #EndpointDataCollection #Webinar
Advancing Alzheimer’s Clinical Trial Endpoints: Imaging Biomarkers, COA Challenges, Movement Measures, and CV Risk | Clario
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Alzheimer's researchers, mark the diary for June 13th Webinar covering Imaging endpoints/eligibility; eCOA assessments; Wearables for gait/movement; CV risk management: agenda and registration below 👇 #alzheimers #clinicaltrials #neuroscience #dementia #biomarkers
Don't miss our next webinar! Clario's experts will explore the critical aspects of conducting clinical trials in Alzheimer’s disease (AD). Topics will focus on: - The role of imaging biomarkers in characterizing patient eligibility, ensuring safety and evaluating therapeutic efficacy - Challenges associated with collecting endpoints for clinical outcome assessments in a changing patient population - Leveraging gait and balance measures for detection and diagnosis of cognitive impairment and dementia and their significance in early intervention -The complexities of running trials in populations at high risk for cardiovascular (CV) disease, emphasizing the importance of baseline testing regardless of the drug being investigated Register now to gain invaluable insights into Alzheimer's disease research: https://lnkd.in/e9FZwuGs #AlzheimersResearch #EndpointDataCollection #Webinar
Advancing Alzheimer’s Clinical Trial Endpoints: Imaging Biomarkers, COA Challenges, Movement Measures, and CV Risk | Clario
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🩸Discover how blood-based biomarkers are set to change Alzheimer's diagnosis and treatment forever!🧠 📰Stay informed and follow for more amazing breakthroughs!✨ 📖Read more: https://bit.ly/45rLqHO 🔮Imagine a future where early detection is possible!💡 #Alzheimers #MedicalBreakthrough #AlzheimersBreakthrough #MedicalEducation #HealthcareProfessionals #eMednews
Blood Biomarkers: Revolutionizing Alzheimer's Diagnosis - eMedNews
https://emed.news
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Phosphorylated-tau 217 (p-Tau 217) has emerged as a potentially crucial biomarker for diagnosing Alzheimer's disease in individuals presenting with cognitive impairment. However, precise measurement is needed to ensure accurate results. Quanterix's proprietary, ultrasensitive Simoa technology enables the measurement of p-tau 217 at very low levels in plasma samples obtained through a simple blood draw. To increase access to p-Tau 217 testing, Lucent Diagnostics, a Quanterix brand, recently introduced LucentAD, a semi-quantitative in vitro diagnostic tool designed to aid in the early diagnosis of Alzheimer's disease. Healio recently interviewed Masoud Toloue, CEO of Quanterix, about p-Tau 217, Lucent Diagnostics, and the forthcoming changes in Alzheimer's disease diagnostics. Explore the full interview: https://bit.ly/3URH6wJ #Alzheimers #Biomarkers #Diagnostics #AlzheimersTreatment
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