Combat Medical Ltd’s Post

Combat Medical Ltd reposted this

View profile for Edward Bruce-White, graphic

CEO & Co-founder, Combat Medical | Transforming cancer treatments through world-leading hyperthermic technologies.

Following on from the last post – describing the first experience of the Combat PRS+ recirculation system with CO2 agitation in Latin America as presented at the 4th Latin American Congress on Peritoneal Neoplasms in Frutillar, Chile last week…   RESULTS   ▶️ CRS included modified radical hysterectomy, bilateral salpingo-oophorectomy, appendectomy, cholecystectomy, splenectomy, major and minor omentectomy, pelvic peritonectomy, bilateral diaphragmatic stripping, and resection of implants on mesenteric and intestinal surfaces. PCI: 20/39; CCS: 0   ▶️ After CRS, four multiperforated catheters were placed: 2 in the upper abdomen (infusion for chemotherapy) and 2 in the lower abdomen (aspiration of CO2 infusion), connected to the CO2 Recirculation System (Combat PRS+A®) with a cavity temperature probe   ▶️ Closed HIPEC performed with OVHIPEC-1 protocol using cisplatin (100 mg/m2) over 90 minutes at 43°C, without complications or alerts. Intervention included cavity fluid washing and closure with intra-abdominal drains   ▶️ The patient stayed in the ICU for 48 hours and was discharged on day 10   ▶️ Postoperative course showed no haematological, renal, or gastrointestinal complications. Histopathology confirmed high-grade serous carcinoma with positive markers (CK7, WT1, PAX8) and HRD positive (BRCA 1/2 not mutated). Treated with Niraparib as maintenance therapy   ▶️ Follow-up at 3 months: excellent response without recurrence   CONCLUSIONS   “The HIPEC technique with CO2 recirculation is safe and reproducible, representing the first experience in Latin America with favorable results. Its application may improve outcomes in patients with peritoneal carcinomatosis and offers an alternative for treatment in advanced peritoneal tumors.”   #medicalinnovation #peritonealcancer #HIPEC #CombatPRS #CombatMedical  

To view or add a comment, sign in

Explore topics