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🔍 Are the Forced Swim Test (FST) and Tail Suspension Test (TST) Still Valid for Depression Research? 🐭 In a recent discussion on www.TheBehaviourForum.org, researchers debated the use of FST and TST for evaluating depression-like behaviors in mice. While these tests measure coping strategies, they fall short in capturing the complexity of depression. Here’s what experts recommend: 📌 Key Takeaways: • FST and TST might oversimplify depression, missing out on the multidimensional nature of mental health conditions. • Suggestions include testing multiple behavioral dimensions, leveraging AI/ML for deeper insights, and developing models that go beyond DSM-5 criteria. ▶️ Swipe through the images to read expert insights and potential solutions for improving preclinical models! 📈 join the discussion in the Forum ! #BehavioralResearch #Neuroscience #MentalHealthResearch #AnimalBehavior #AIinScience #LinkedInScience

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Benoit Petit-Demouliere

Responsable de Département - Citoyen actif - Impliqué dans le caritatif et l'éthique

3w

Great summary of this discussion !

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