🌟 New Publication Alert! 🌟 We’re excited to officially announce our publication boosting cryo-EM workflow efficiency in the Journal of Structural Biology! 🚀 This study demonstrates how ice thickness can be easily controlled and measured within the VitroJet. 🎥 By assessing ice thickness during sample prep, we can save valuable microscope screening and data collection time. ⏰ The innovative approach has already shown to require 3.7x fewer particles for structure determination, speeding up workflows and enhancing productivity! 🔬 🔗 Read the full publication here: https://lnkd.in/dmG9-Q5Q 👏 A huge thanks to our collaborators and team for making this possible. 🌍 #CryoSolWorld #VitroJet #CryoEM #MicroscopeEfficiency #StructuralBiology #Innovation
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The University of Alberta and National Research Council Canada / Conseil national de recherches Canada authors Robert Peters, Luis Gutierrez-Rivera, Steven Dew, and Maria Stepanova in their paper "Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using #EBL Fabricated Nanostructured Substrates" fabricate and characterize conjugate nano-biological systems interfacing metallic nanostructures on solid supports with immobilized biomolecules. The fabrication of nanostructured substrates using #electron #beam #lithography, immobilization of biomolecules on the substrates, and their characterization utilizing surface-enhanced #Raman #spectroscopy (#SERS) are discussed. Three different designs of nano-biological systems are employed, including protein A, glucose binding protein, and a dopamine-binding #DNA aptamer. The binding of respective ligands, D-glucose and dopamine, is also included in the latter two cases. The three kinds of biomolecules are immobilized on nanostructured substrates by different methods, and the results of SERS imaging are reported. The capabilities of SERS to detect vibrational modes from surface-immobilized proteins, as well as to capture the protein-ligand and aptamer-ligand binding are demonstrated. The results also illustrate the influence of the surface nanostructure geometry, biomolecules immobilization strategy, the molecules' Raman activity, and the presence or absence of the ligand binding on the SERS spectra acquired. Read More: https://lnkd.in/eqXATeBz
Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
pmc.ncbi.nlm.nih.gov
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I'm thrilled to announce that our latest research has been published in the International Journal of Solids and Structures! 📄🔬 Title: A novel in-situ micro-mechanical testing of paper fracture and its stochastic network model Read the full article here: https://lnkd.in/d_fc6_dD In this study, we investigated the fracture mechanics of cellulose-based paper materials, which are crucial for eco-sustainable packaging solutions. Through a combination of in-situ tensile tests and confocal microscopy using the facilities available at the MUSAM lab at Scuola IMT Alti Studi Lucca, we analyzed the microstructural mechanisms that influence paper fracture. Our developed stochastic network model accurately predicts the anisotropic properties of paper materials and provides new insights into the mechanical behavior of paper. A huge thank you to the authors, specifically to my supervisor, Professor Marco Paggi, for his invaluable coaching and guidance, and to my colleague, Hamed Zarei, for his significant contributions to this work. This achievement would not have been possible without your support. #Research #SustainablePackaging #MaterialScience #PaperMechanics #Micromechanics #StatisticalModeling
A novel in-situ micro-mechanical testing of paper fracture and its stochastic network model
sciencedirect.com
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Achieve precision with cutting-edge grating technology. Are you working on advanced optical systems in industries like spectroscopy, telecommunications, or biotechnology? Selecting the right diffraction grating can make all the difference in achieving precision, efficiency, and durability. Our latest White Paper dives into the world of holographic diffraction gratings, exploring their role in modern optical systems and offering expert insights into their design, selection, and application. 💡 What You’ll Gain: ➡️A clear understanding of how diffraction gratings separate light for precise applications. ➡️Insights into the strengths of holographic gratings and how they compare to other types. ➡️Practical guidance for overcoming technical challenges when choosing gratings. ➡️Real-world examples showcasing Omega Optical’s innovation and expertise. Whether you're an engineer, scientist, or researcher looking to enhance your optical designs, this White Paper is your go-to guide for making informed decisions about diffraction gratings. 🛠️ Learn how Omega Optical can deliver customised, high-quality solutions tailored to your needs, with a proven track record of successful collaborations. 📥 Download the White Paper now and take your optical systems to the next level: https://lnkd.in/eUiuva_B Let’s transform the way you approach light dispersion. 🚀 #OpticalEngineering #Spectroscopy #DiffractionGratings #Telecommunications #Biotechnology #Innovation
Holographic diffraction gratings for advanced optical systems | Electro Optics
electrooptics.com
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Finally! After a long and rigorous review process, I am pleased to announce that our latest paper, "Molecular Strong Coupling and Cavity Finesse," has been published in JPCL. Our research demonstrates that the effectiveness of molecular strong coupling critically depends on cavity finesse. Previous reports on open cavities have noted changes in molecular absorption but have not conclusively shown effective chemical control. Our study explores photoluminescence in open, half, and full cavities to gain deeper insights into cavity-free strong coupling. This research identifies an additional requirement for effective molecular strong coupling, underscoring the essential role of cavity finesse in controlling chemistry. Dive into our groundbreaking work and discover more! #Research #Physics #CavityFinesse #Photoluminescence #StrongCoupling #MolecularScience #JPCL
Molecular Strong Coupling and Cavity Finesse
pubs.acs.org
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🔋 New Research results on Polymer-Based Batteries! 🔋 Did you know that the performance of next-gen polymer-based batteries hinges on the complex 3D structure of their electrodes? Our latest study dives deep into this relationship, using focused ion beam scanning electron microscopy (FIB-SEM) to analyze and compare three different polymer-based electrode materials. Through advanced 3D imaging and simulations, we've developed analytical formulas to predict how electrode morphology impacts ion and electron transport—a groundbreaking first at the nanometer scale! Discover how this work could help shape the future of high-density, eco-friendly batteries. Authors: Benedikt Prifling, Lukas Fuchs, Aigerim Yessim, Markus Osenberg, Melanie Paulisch-Rinke, Philip Zimmer, Martin Hager, Ulrich S. Schubert, Ingo Manke, Thomas Carraro, Volker Schmidt https://lnkd.in/e-dR3Jvy #polymer #polymerbatteries #battery #article #3DMorphology #batteryelectrodes #chemistry #chemistryresearch
Correlating the 3D Morphology of Polymer-Based Battery Electrodes with Effective Transport Properties
pubs.acs.org
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Exciting new review about the innovative use of laser techniques in developing and functionalizing biomimetic surfaces! 🐞 🌿 📜 Advanced Laser Techniques for the Development of Nature-Inspired Biomimetic Surfaces Applied in the Medical Field 🔑 #biomimetic #materials; #surface #functionalization; #lasertechniques Read and download for FREE 👉 https://lnkd.in/ddTfuSD8 🎓 By Anita Ioana Visan and Gianina Florentina Popescu-Pelin 🏛 National Institute for Lasers, Plasma and Radiation This review focuses on the innovative use of laser techniques in developing and functionalizing biomimetic surfaces, emphasizing their potential applications in the medical and biological fields. Drawing inspiration from the remarkable properties of various natural systems, such as the water-repellent lotus leaf, the adhesive gecko foot, the strong yet lightweight spider silk, and the unique optical structures of insect wings, we explore the potential for replicating these features through advanced laser surface modifications. Depending on the nature and architecture of the surface, particular techniques have been designed and developed. We present an in-depth analysis of various methodologies, including laser ablation/evaporation techniques, such as Pulsed Laser Deposition and Matrix-Assisted Pulsed Laser Evaporation, and approaches for laser surface structuring, including two-photon lithography, direct laser interference patterning, laser-induced periodic surface structures, direct laser writing, laser-induced forward transfer, and femtosecond laser ablation of metals in organic solvents. Additionally, specific applications are highlighted with the aim of synthesizing this knowledge and outlining future directions for research that further explore the intersection of laser techniques and biomimetic surfaces, paving the way for advancements in biomedical applications. #review #peerreviewed #openaccess #callforreading #scientificpublishing #mdpi #mdpicoatings
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🌟 Excited to share the Title Story, Volume 10, Issue 4: Fabrication of Hydrogel-Based Composite Fibers and Computer Simulation of the Filler Dynamics in the Composite Flow. 🥼 This paper is authored by Thomas Gruhn, Camilo Ortiz Monsalve, Claudia Müller, Susanne Heid, Aldo R. Boccaccini and Sahar Salehi. 💡 Fibrous structures with anisotropic fillers as composites have found increasing interest in the field of biofabrication since they can mimic the extracellular matrix of anisotropic tissues such as skeletal muscle or nerve tissue. In the present work, the inclusion of anisotropic fillers in hydrogel-based filaments with an interpenetrating polymeric network (IPN) was evaluated and the dynamics of such fillers in the composite flow were analyzed using computational simulations. Welcome to view this paper here👉 : https://lnkd.in/gMJdihYH. #composite_filaments #anisotropy #microrods #wet_spinning #computational_simulation
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Friction is essential in our daily lives by enabling motion and providing traction, but it also results in enormous material and energy losses. Biological species such as snakes display unusual frictional anisotropy via microscopic patterned surfaces, which helps their locomotion. Bioinspired nano/micro texturing with frictional anisotropy can find fascinating applications by designing mobile and immobile surfaces for MEMS/NEMS devices, nano/microrobots, medical devices, etc., as well as controlling the tribological properties and minimizing energy loss in existing industrial components. Our new research article provides insights into controlling the anisotropic frictional behavior using titania nanorod patterning developed through the glancing angle deposition (GLAD) technique. The directional stick-slip friction of the nanopatterned surface can be systematically controlled via rotation of the textured surface with respect to the sliding direction. Our recent work, led by PhD scholar DEBOTTAM DATTA, is now published in ACS Applied Materials and Interfaces (https://lnkd.in/gCAtX_2X). #friction #StickSlip, #Nanotribology, #NanotexturedSurface, #NanoMission, #DST, #IITDelhi, #Nanosurf, #AtomicForceMicroscopy
Anisotropic Stick–Slip Frictional Surfaces via Titania Nanorod Patterning
pubs.acs.org
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Absolute configuration determination by Electron Diffraction. Are you aware that #ElectronDiffraction (#3D ED, #MicroED) can also determine the #absoluteconfiguration of your molecule? Yes, it can! With #dynamicalrefinement. This is a refinement procedure that goes beyond traditional kinematical approximations in electron diffraction analysis. It takes into account the effect of multiple diffraction events contributing to each reflection. This advanced method allows not only for a more precise and reliable structure refinement, but also for determination of the #absolutestructure. #ELDICOScientific has the equipment, skills, software, and knowledge to perform this analysis on your samples. https://lnkd.in/e2utSqcx ELDICO Scientific AG provides service as a measurement so you can see the benefits of using Electron Diffraction on your nanocrystals! Book a demo or send your sample. Our skilled application team will be happy to work with you and find the best solution. Save time, resource and material since you do not need to grow large single crystals anymore. Just send your powder sample to us. For more information contact us! https://lnkd.in/eFJyQ9vz Or watch our past seminar with invited speakers Lukas Palatinus and Paul Klar. https://lnkd.in/eFixCYJR #electrondiffraction #electrondiffractometer #electroncrystallography #nanocrystallography #amorphicity #MaterialScience #ScienceEducation #microED #amorphous #crystalstructure #crystallography
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Excited to announce the publication of our paper in the Q1 journal Polymers MDPI, which is Open Access for all to read! Five years after completion, it is rewarding to see my master's work still making significant contributions to its field and being recognized in a leading journal! In this paper, we present elasto-static analysis of dental restorations under various loading conditions, namely occlusal forces and bruxism. We compared the structural responses of three commercial dental composite materials to that of an "intact" molar tooth. Among these, Z100™ by 3M stood out for its superior performance under stress. A significant aspect of our study was the use of computational methods, including the finite element method (FEM) and meshless techniques such as RPIM and NNRPIM. The meshless methods demonstrated excellent accuracy, particularly, near complex curves, compared to conventional FEM. For instance, hereunder, you can see the schematic representation of left-oriented bruxism loading condition modelled in the absence of an adjacent tooth to the left. Also, three contour plots illustrate stress analysis conducted using FEM and meshless methods (RPIM and NNRPIM) on restored molar tooth by Z100™. A special thank you to my master's thesis advisor Jorge Belinha and my dear colleague Behzad Vasheghani Farahani for their invaluable support and contribution to this research. I encourage those with an interest in dental material sciences and computational analysis to explore our paper: https://lnkd.in/eeA7SVcb Your insights and discussions are most welcome! #DentalMaterials #ComputationalAnalysis #FiniteElementMethod #MeshlessMethods #FEA #ElastoStaticAnalysis #StressAnalysis #DentalRestorations
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