I will talk about this and other single carbon substrates for biotechnology at the International Congress on Yeasts in Cape Town (29 Sept - 3 Oct). Yeast people, if you are not registered yet, there is still the opportunity. Also for poster abstract submission: www.icy2024.com #yeast #biotechnology
Happy to share the latest paper of our lab at Universität für Bodenkultur Wien . Simone Bachleitner Manja Mølgaard Severinsen and Gregor Lutz demonstrate how to engineer the yeast Komagataella phaffii to produce lactic acid from methanol. Trickier than thought, as lactic acid turned out to inhibit methanol utilization, creating a negative feedback loop. The work is part of the VIVALDI H2020 project https://lnkd.in/dgDHWqEE