Diptendu Sekhar Biswas’ Post

https://lnkd.in/egEPsGfE The start-up ecosystem in life sciences, Stakeholders in a start-up, Basic v/s translational research, and health systems 

#HighlyCitedPapers   📝 Drug-Targeted Genomes: Mutability of Ion Channels and GPCRs — Raines, et al.   In this paper, the authors aimed to provide an exciting new approach for the mapping of druggable genes and potential drug targets.   Full text is available 👇 https://lnkd.in/d-RGWG8P   #medicine #health #research #science

🌟 Another Successful Webinar Completed! 🌟 Yesterday, Heredity Biosciences hosted an insightful webinar on "Nanotoxicity: A Challenge for Future Medicines." A huge thank you to Dr. Piyush Kumar Gupta 🇮🇳 for delivering an exceptional talk and sharing valuable insights. We're also grateful to all our active participants for their enthusiastic engagement and contributions to the discussion. 🎥 If you missed the live session, don't worry! You can now watch the recording at your convenience. Click the link below to access the webinar recording: [https://lnkd.in/gSXssW3r) Don't miss out on this opportunity to learn and stay informed about the latest developments in nanotoxicity research. Watch the recording today and enhance your knowledge in this important field. #Nanotoxicity #FutureMedicine #HeredityBiosciences #WebinarRecording #Science #Research #LearningOpportunity #hereditybio

𝗗𝗮𝘆 𝟰𝟬, 𝗣𝗮𝘀𝘀𝗮𝗴𝗲 𝟯: 𝗪𝗶𝘁𝗻𝗲𝘀𝘀𝗶𝗻𝗴 𝘁𝗵𝗲 𝗚𝗿𝗼𝘄𝘁𝗵 𝗼𝗳 𝗧𝗶𝗻𝘆 𝗠𝗶𝗿𝗮𝗰𝗹𝗲𝘀 🌱 It's been a dedication and hard work journey, but the organoids growing at King Faisal Specialist Hospital and Research Center labs are thriving! Here's a closer look into the world of organoid cultivation: • Patience is Key: Growing organoids requires care, precise protocols, and patience. ⏳ • Learning from Mistakes: Not every experiment goes as planned. We've faced challenges, but each setback is a valuable learning opportunity, pushing us closer to success. 💡    • The Future is Bright: These tiny organ-like structures hold potential for disease modeling, drug testing, and understanding disease development.      We're excited to see what the future holds! 🚀 #organoids #medicalresearch #stemcells #biotechnology #researchlife #science #futureofmedicine # #Bioengineering #KFSHRC

#ParticularInterestPaper   📝 Zika M—A Potential Viroporin: Mutational Study and Drug Repurposing — Tomar, et al.   In this paper, the authors focussed on the characterization of matured #Zika virus M protein as a potential viroporin utilizing three different bacteria-based assays   Full text is available 👇 https://lnkd.in/dCKz-r2K   #medicine #health #research #science

https://lnkd.in/g6CQcWZF Abstract The #gut #microbiome harbors trillions of organisms that contribute to human health and disease. These #bacteria can also affect the properties of medical #drugs used to treat these diseases, and drugs, in turn, can reshape the microbiome. Research addressing interdependent microbiome-host-drug interactions thus has broad impact. In this Review, we discuss these interactions from the perspective of drug bioavailability, absorption, metabolism, excretion, toxicity, and drug-mediated microbiome modulation. We survey approaches that aim to uncover the mechanisms underlying these effects and opportunities to translate this knowledge into new strategies to improve the development, administration, and monitoring of medical drugs.

I am looking forward to this panel discussion on cross-country collaboration and how we can support innovation!

Think of drug repurposing like a Swiss Army knife. 💊 Just as these tools have multiple functions - like cutting, opening bottles, or even sawing - some medicines can be used to treat more than one illness! To showcase the latest advancements in drug repurposing research, highlight successful case studies, and address the challenges and opportunities in this field, Claudia Fuchs, our Drug Repurposing Projects Senior Manager, is guest-editing a Special Issue of the International Journal of Molecular Sciences (IJMS). Entitled “Drug Repurposing in Rare Diseases: From Molecular Insights to Patient Benefits.”, the aim of this project is to help illuminate new therapeutic pathways and foster collaboration in this vital area of research. Researchers, clinicians, and patient advocates are invited to submit their manuscripts today! Deadline: 30 November, 2024. Learn more 👉 https://lnkd.in/eKErqDSn #RareDiseases #DrugRepurposing #research #collaboration #publication

Eravacycline is a novel antibiotic of the tetracycline class with activity against a broad spectrum of clinically significant bacteria, including multi-drug-resistant organisms. In this paper, the authors aimed to assess the in vitro effectiveness of eravacycline to carbapenemase-producing Gram-negative bacilli clinical isolates identified in hospitals in Łódź, Poland. 📝 In Vitro Activity of Eravacycline against Carbapenemase-Producing Gram-Negative Bacilli Clinical Isolates in Central Poland — Brauncajs, et al. Full text is available 👇 https://lnkd.in/dR3ENj2n #medicine #health #research #science