European Foundation for the Study of Chronic Liver Failure (EF CLIF)’s Post

Last week, a delegation of EU-LIFE attended the #EUResearchArea Conference and the 26th #ERA Forum meeting. Marta Agostinho, EU-LIFE Executive Director, advocated for a constructive policy to #AnimalResearch and the development of new approach methodologies (#NAMs) following the active role of EU-LIFE in the co-creation of the ERA action on this topic. Her main points were: • 𝗔𝘀 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗶𝗻𝘀𝘁𝗶𝘁𝘂𝘁𝗲𝘀 𝘄𝗲 𝗮𝗿𝗲 𝗳𝘂𝗹𝗹𝘆 𝗰𝗼𝗺𝗺𝗶𝘁𝗺𝗲𝗻𝘁 𝘁𝗼 𝘁𝗵𝗲 𝗱𝗲𝘃𝗲𝗹𝗼𝗽𝗺𝗲𝗻𝘁 𝗮𝗻𝗱 𝘂𝘀𝗲 𝗼𝗳 𝗡𝗔𝗠𝘀 that help to reduce the use of animals in research and regulatory testing. Likewise, we are fully committed to the Three Rs principle (Replacement, Reduction and Refinement). • Researchers are the ones developing NAMs, so 𝘁𝗵𝗲 𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝗳𝗶𝗰 𝗰𝗼𝗺𝗺𝘂𝗻𝗶𝘁𝘆 𝗶𝘀 𝗮 𝗸𝗲𝘆 𝗽𝗹𝗮𝘆𝗲𝗿 for the success of any policy on NAMs and must be part of it at all stages. • The main value of this ERA action is the capacity to 𝗽𝗿𝗼𝗺𝗼𝘁𝗲 𝗰𝗼𝗼𝗿𝗱𝗶𝗻𝗮𝘁𝗶𝗼𝗻 𝗮𝗺𝗼𝗻𝗴 𝗠𝗲𝗺𝗯𝗲𝗿 𝗦𝘁𝗮𝘁𝗲𝘀, most specially at the regulatory stage; global coordination beyond the EU is also critical. • This action will only contribute to EU competitiveness if it allows the advancement of biomedical research and helps move science forward, 𝗯𝗮𝘀𝗲𝗱 𝗼𝗻 𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝗳𝗶𝗰 𝗰𝗿𝗶𝘁𝗲𝗿𝗶𝗮 and not on political timelines. • The 𝘁𝗿𝗮𝗶𝗻𝗶𝗻𝗴 𝗮𝗻𝗱 𝗲𝗱𝘂𝗰𝗮𝘁𝗶𝗼𝗻 component of the action towards all actors - researchers, regulators, policy makers and citizens - is paramount. Informed policies must be based on broader understanding of the complexity of the biology behind biomedical research and on the potential risks, gains and impacts of the policies. Find out more here 🔗 https://bit.ly/3XUYnI0 #EuropeanResearch #ExcellentResearch

🔬👩🏼🔬 Call for the scientific community to research on #AlternativesToAnimalTesting🔬👩🏼🔬 The European Chemicals Agency has identified areas where more scientific research is needed to shift away from animal testing: read-across and NAMs, In vitro/in silico ADME, Physiologically-Based Kinetic models, fish toxicity, and carcinogenicity. 📘 Check out the report on these critical research needs and many other areas where you can contribute. 🔗https://lnkd.in/dVfniKhq Get inspired, get involved - #ECHAscience

🔬👩🏼🔬 Call for the scientific community to research on #AlternativesToAnimalTesting🔬👩🏼🔬 The European Chemicals Agency has identified areas where more scientific research is needed to shift away from animal testing: read-across and NAMs, In vitro/in silico ADME, Physiologically-Based Kinetic models, fish toxicity, and carcinogenicity. 📘 Check out the report on these critical research needs and many other areas where you can contribute. 🔗https://lnkd.in/dVfniKhq Get inspired, get involved - #ECHAscience

🔬👩🏼🔬 Call for the scientific community to research on #AlternativesToAnimalTesting🔬👩🏼🔬 The European Chemicals Agency has identified areas where more scientific research is needed to shift away from animal testing: read-across and NAMs, In vitro/in silico ADME, Physiologically-Based Kinetic models, fish toxicity, and carcinogenicity. 📘 Check out the report on these critical research needs and many other areas where you can contribute. 🔗https://lnkd.in/dVfniKhq Get inspired, get involved - hashtag#ECHAscience

🔬👩🏼🔬 Call for the scientific community to research on #AlternativesToAnimalTesting🔬👩🏼🔬 The European Chemicals Agency has identified areas where more scientific research is needed to shift away from animal testing: read-across and NAMs, In vitro/in silico ADME, Physiologically-Based Kinetic models, fish toxicity, and carcinogenicity. 📘 Check out the report on these critical research needs and many other areas where you can contribute. 🔗https://lnkd.in/dVfniKhq Get inspired, get involved - hashtag#ECHAscience

🔬👩🏼🔬 Call for the scientific community to research on #AlternativesToAnimalTesting🔬👩🏼🔬 The European Chemicals Agency has identified areas where more scientific research is needed to shift away from animal testing: read-across and NAMs, In vitro/in silico ADME, Physiologically-Based Kinetic models, fish toxicity, and carcinogenicity. 📘 Check out the report on these critical research needs and many other areas where you can contribute. 🔗https://lnkd.in/dVfniKhq Get inspired, get involved - #ECHAscience

Having started my career with scientific research in toxicology (more than 10 years ago) my biggest challenge was facing the animal test. At the time I discovered loads of software capable to perform this kind of analysis. Can you imagine today with the exponential AI development? But the software still need human inputs, so please if you are a researcher don't miss the opportunity to make the world better. #sustainability #sustainableresearch

Not easy to stay up to date all the time, but have a loock to this ECHA report from June which ECHA's expectations for new methods, preferably non-animal. "Key Areas of Regulatory Challenge, June 2024" https://lnkd.in/e6tTaeM6 #ECHA , #toxicology #neurotoxicology

🔎🔎#ECHA and Alternatives to #Animaltesting: A call for your contribution‼️📌⬇️👇🏼 “🔬👩🏼🔬 Call for the scientific community to research on #AlternativesToAnimalTesting🔬👩🏼🔬 The European Chemicals Agency has identified areas where more scientific research is needed to shift away from animal testing: #readacross and #NAMs, #Invitro/#insilico #ADME, #PhysiologicallyBasedKinetic #models, #fishtoxicity, and #carcinogenicity. 📘 Check out the report on these critical #research needs and many other areas where you can contribute. 🔗https://lnkd.in/dVfniKhq Get inspired, get involved - #ECHAscience”

🔬👩🏼🔬 Call for the scientific community to research on #AlternativesToAnimalTesting🔬👩🏼🔬 The European Chemicals Agency has identified areas where more scientific research is needed to shift away from animal testing: read-across and NAMs, In vitro/in silico ADME, Physiologically-Based Kinetic models, fish toxicity, and carcinogenicity. 📘 Check out the report on these critical research needs and many other areas where you can contribute. 🔗https://lnkd.in/dVfniKhq Get inspired, get involved - #ECHAscience