📍 Study reveals clearer picture of hypertension’s impact on brain health Excerpt: A Centre for Healthy Brain Ageing (CHeBA) study provides compelling evidence for clinical practice to direct efforts toward preventing white matter damage in individuals with hypertension, to protect against cognitive decline and dementia. High blood pressure has a negative effect on many aspects of health and is also known to affect both the grey and white matter in the brain during the ageing process. Grey matter is where the brain cells exist, whereas white matter constitutes the network of nerve fibres that provides the communication connection between different areas of grey matter. The study, led by Dr Jing Du and Associate Professor Wei Wen and published March 11, 2024 in Hypertension (https://lnkd.in/ea9ZSXpN), found that compared with grey matter, white matter is more vulnerable to raised blood pressure. Because grey matter has a greater amount of small blood vessels, and therefore a greater supply of blood compared to white matter, we wanted to see if white matter is more susceptible to damage from reduced blood flow caused by high blood pressure, Dr Jing Du. Because grey matter has a greater amount of small blood vessels, and therefore a greater supply of blood compared to white matter, we wanted to see if white matter is more susceptible to damage from reduced blood flow caused by high blood pressure. We applied advanced technology known as the 3D-CNN deep learning model to measure the grey matter and white matter brain ages separately said Dr Jing Du. The researchers looked at brain scans from nearly 40,000 people with varying levels of blood pressure, ranging from normal to high. They found that as blood pressure increased, both grey and white matter showed signs of ageing, with white matter appearing to age faster. The findings suggest that memory and thinking problems are more likely to occur as a result of high blood pressure’s impact on white matter, rather than grey matter. The researchers also investigated how different aspects of blood pressure affect brain ageing. They found that systolic blood pressure had a linear relationship with both grey and white matter ageing – meaning as blood pressure increases, so does brain ageing. On the other hand, diastolic blood pressure had a U-shaped relationship, suggesting an optimal range for maintaining brain health. The study suggests that white matter in the brain is particularly vulnerable to high blood pressure. To preserve brain health, it is crucial to keep blood pressure within an optimal range. Managing blood pressure effectively could help protect against cognitive decline and future efforts should focus on monitoring and managing white matter health in people with high blood pressure. Dr Jing Du Read more ➡ https://lnkd.in/eX66tESw #hightbloodpressure #hypertension #brainhealth #dementia #mriscan #neuroimaging #radiology #publichealth #saltintake #diet
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Recent findings published in Nature Portfolio spotlight how vascular issues in the brain may affect cognitive health in type 1 diabetes. The research showed blocking certain inflammatory signals could reduce capillary blockages and improve cognitive outcomes. This research emphasizes the importance of studying brain health in diabetes to uncover new ways to safeguard cognitive function. Read about the findings here: https://lnkd.in/eEmH97fa #DiabetesAwarenessMonth #BrainHealth #DiabetesResearch
A pathogenic role for IL-10 signalling in capillary stalling and cognitive impairment in type 1 diabetes - Nature Metabolism
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"A new study published in Scientific Reports sheds light on long-term neurological consequences of #Covid19. Researchers found that individuals who had anosmia (the loss of smell) during COVID-19 showed alterations in brain functionality and even physical structure during recovery. This study is among the first to link COVID-19-related loss of smell to significant brain changes." #santé #Gesundheit #Corona #health https://lnkd.in/dziWfin8
Scientists discover troubling brain changes in COVID-19 patients who lost sense of smell
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Long COVID is a persistent and complex condition affecting many worldwide. With symptoms like fatigue, depression, and brain fog, it poses significant challenges to treat. Emerging evidence now suggests that non-invasive brain stimulation might be a promising solution. 🔗 We've summarized the latest research on non-invasive brain stimulation for treating long COVID symptoms. Link in comments below 👇 Transcranial Magnetic Stimulation (#TMS) is a non-invasive treatment that has already proven effective for persistent conditions like depression and chronic pain. Recent studies have shown improvements in cognitive function, reductions in fatigue, anxiety, and depression, and even increases in IQ for long COVID patients treated with TMS. Transcranial Direct Current Stimulation (#tDCS) is another non-invasive treatment used for chronic neurological conditions. Early research shows that tDCS can improve symptoms including fatigue, attention, memory, and executive function in long COVID. Learn more about non-invasive brain stimulation treatments on our website. #LongCOVID #TMS #BrainHealth #Neuromodulation #MentalHealth #NonInvasiveTherapy #COVID19Recovery #LongCOVID
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Non-US IMG | NMU | Clinical Researcher | USMLE Aspirant | Looking for Research & Observership Opportunities |ECFMG Certified| Research Fellow at TGRF Michigan State University, MI, USA| MATCH 2024 applicant.
🚨 New Publication Alert: The Impact of COVID-19 on Neurological Health – A Case of Post-COVID-19 Rasmussen Encephalitis 🚨 In my latest publication, I explore a rare but severe case of Rasmussen encephalitis (RE) triggered by COVID-19, emphasizing the importance of early recognition and intervention in post-COVID neurological complications. 🧠 Key Highlights: A 30-year-old woman, recently diagnosed with COVID-19, developed recurrent seizures and progressive neurological decline. Despite treatment, she was ultimately diagnosed with post-COVID-19 RE, and her condition worsened, resulting in fatal outcomes. This case raises crucial concerns about the autoimmune effects of COVID-19 on the brain, calling for increased awareness and research into its long-term neurological impact. 🔍 Takeaway: Early detection and intervention are crucial in managing rare neurological complications like RE. Further studies are needed to understand and improve the management of COVID-19’s neurological aftermath. Read the full study to learn more about this pressing issue and its implications for future neurological health management.
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Long COVID is a persistent and complex condition affecting many worldwide. With symptoms like fatigue, depression, and brain fog, it poses significant challenges to treat. Emerging evidence now suggests that non-invasive brain stimulation might be a promising solution. 🔗 We've summarized the latest research on non-invasive brain stimulation for treating long COVID symptoms. Link in comments below 👇 Transcranial Magnetic Stimulation (#TMS) is a non-invasive treatment that has already proven effective for persistent conditions like depression and chronic pain. Recent studies have shown improvements in cognitive function, reductions in fatigue, anxiety, and depression, and even increases in IQ for long COVID patients treated with TMS. Transcranial Direct Current Stimulation (#tDCS) is another non-invasive treatment used for chronic neurological conditions. Early research shows that tDCS can improve symptoms including fatigue, attention, memory, and executive function in long COVID. Learn more about non-invasive brain stimulation treatments on our website. #LongCOVID #TMS #BrainHealth #Neuromodulation #MentalHealth #NonInvasiveTherapy #COVID19Recovery #LongCOVID
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I help people obtain their weight loss and wellness goals using GLP1-RAs, compounded Semaglutide & Tirzepatide, diet and exercise planning. Find transformative medicine at omnihealth.live. Founder & CEO of Òmni Health NP
Begging questions... Should we have GLP-1 on the Brain? GLP-1 is mostly known for its effect on the gut; slowing gastric emptying, and decreasing hunger, thereby promoting weight loss. But GLP-1 is also produced in the brain. It plays a crucial role in neuroprotection by activating GLP-1 receptor pathways which enhances learning and memory in the hippocampus, promotes neurogenesis (brain cell building), reduces inflammation and apoptosis (brain cell death), modulates reward behavior (less cravings), and also decreases food intake. Conversely, obesity has been shown to hasten dementia and cognitive decline especially in mid-life. This phenomenon begs the question as to whether the inflammation caused by weight-related diseases (i.e. obesity) perpetuates poor eating habits due to a subsequent decline in executive brain functioning. Interestingly, studies have not shown that simply losing weight will improve brain health in patients with diabetes. So what can we do? How can we use this information to move the needle of longevity (emphasis on long) in the right direction? Could we use GLP1-RAs or GIP/GLP1-RAs like semaglutide or tirzepatide to activate the GLP1 pathway, induce fat loss, and prevent the pro-inflammatory conditions that lead to neurological disease? Not just as a function of the weight loss, which is one benefit, but also through the action of the drug? We don't have many options for the treatment of neurodegenerative diseases like dementia. But neuroplasticity (brain remodeling) is a thing. Access yours. omnihealth.live
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AccendoWave - A Pain #Data Company Researchers in China and the U.S. have found that chronic musculoskeletal pain (CMP) could be linked to a higher risk of brain aging and dementia. People with knee osteoarthritis were found to have more rapid brain aging than people without it. A genetic link between inflammation and brain function may point toward a way to predict cognitive decline, but further study is needed, experts say. A Top 4 Global Health Equity Solution and Top 15 Global Remote Monitoring Company, AccendoWave, benchmarks objective brain wave pain data (specialty, gender, age) and has nine #pain databases: Emergency Department, Maternal Health, Oncology, MSK, Medical Surgical, ICU, Women, Adults, Seniors to eliminate bias, improve outcomes and reduce health care costs. If desired, AccendoWave can also create customized pain databases for partners that can be accessed on the Datavant platform. https://lnkd.in/g6QiwxSR?
Dementia: Chronic musculoskeletal pain may speed up brain aging
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AccendoWave - A Pain #Data Company In a study published in Nature Mental Health, scientists from China and the United States have found that individuals suffering from chronic musculoskeletal pain (CMP) may face a higher high risk of brain aging. CMP is a leading cause of disability, affecting more than 40% of the world's population and impacting patients' cognitive function. Although the exact mechanism is not fully understood, thus hampering prevention and treatment efforts, research indicates that inflammatory markers associated with brain aging are higher in CMP patients, suggesting a link between brain aging and CMP. A Top 4 Global Health Equity Solution and Top 15 Global Remote Monitoring Company, AccendoWave, benchmarks objective brain wave pain data (specialty, gender, age) and has nine #pain databases: Emergency Department, Maternal Health, Oncology, MSK, Medical Surgical, ICU, Women, Adults, Seniors to eliminate bias, improve outcomes and reduce health care costs. If desired, AccendoWave can also create customized pain databases for partners that can be accessed on the Datavant platform.
Chronic musculoskeletal pain may accelerate brain aging
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Study challenges traditional risk factors for brain health in the oldest-old A study led by the University of California, Irvine has found cardiovascular conditions such as high blood pressure and diabetes, which are known to contribute to brain blood vessel damage in younger populations, not to be associated with an increased risk of such harm in individuals 90 and older. https://lnkd.in/d7R9yZNu
UC Irvine-led study challenges traditional risk factors for brain health in the oldest-old
https://news.uci.edu
CEO | A Healthier Democracy | Physician
10moAmazing insights into the impact of hypertension on brain health! Emma P. 👏🏽 This study sheds light on the importance of preventing white matter damage to safeguard against cognitive decline and dementia. 🙌🏽