EquipmentTrader’s Post

UPTON Sealing Test | Pharmaceutical Packaging Sealing Integrity Solution [Testing object] There are many drugs that need to be tested for packaging sealing in the pharmaceutical industry. The common ones include the following three categories: Sealed containers: vials, ampoules, syringes, oral liquids, sterile bags, infusion bags/bottles, water injections, powder injections, BFS bottles, API bottles, BPC bottles, FFS bottles and other closed containers. Blister packaging: samples of powders, tablets, capsules, contact lenses, etc. that are packaged in blister packaging. Small headspace packaging: granules packaging, small-dose pharmaceutical powders and other packaging with extremely small headspace. [Testing plan] In order to solve customers' problems, Shangteng Technology provides mature pharmaceutical packaging sealing integrity solutions. Option 1: Use a new generation of M90 pharmaceutical packaging leak tester from UPTON Technology, which can be applied to various types of packaging. In addition, the instrument is simple and fast to operate, and the results are reliable. [Instrument features] 1. The M90 pharmaceutical packaging sealing tester conducts qualitative and quantitative analysis of the sealing integrity of the packaging by precisely measuring the pressure or flow of air molecules escaping from defects in pharmaceutical packaging. It is an advanced high-precision non-destructive testing method. 2. The M90 is based on the core scientific and technological achievements accumulated in the early stage and is specially optimized for high-precision inspection of pharmaceutical packaging. The M90 is made of a lightweight and strong aluminum alloy shell, reaching the IP63 protection level and has excellent anti-electromagnetic interference capabilities. 3. The high-performance embedded Linux system supports advanced command interaction and operates stably. M90 takes into account both desktop use and automation cabinet integration. The core components of M90 are all independently developed. The special control valve we invented uses pneumatic control energy, which greatly reduces the heat interference of traditional electric-driven valves. Option 2: Use S20 sealing leak detector of UPTON Technology, with a testing aperture of 2μm (micron). Air tightness test standard unit, screen and machine separation [Instrument features] 1. Air leak test standard unit, screen and machine separation 2. Modular appearance design, convenient for centralized installation 3. Pressure range covers -100kPa to 2000kPa (2MPa) 4. Suitable for standardized large-volume testing, and can control multiple instruments to work simultaneously through the host computer

Improving dispensing of a nanoparticulate formulation in manufacturing Biotech Fluidics reports on the successful development and implementation of a pioneering combined micro flowmeter and degasser set-up to improve dispensing of a nanoparticulate formulation for a leading medical technology company. To ensure the accuracy of spray coating of the pharmaceutical formulation onto a medical device the CMO turned to Biotech Fluidics because of their experience in creating turnkey fluidics systems and expertise in degassing. #NanoparticleDispensing #ManufacturingInnovation #NanotechManufacturing #PrecisionDispensing #NanoparticleFormulation Biotech Fluidics https://lnkd.in/e4ttQttd

🍓 至言去言，至为去为。——《庄子·知北游》 The most profound words are those left unsaid; the greatest deeds are those not done intentionally.🍓 ⟨381⟩ Elastomeric Closures for Injections, USP 40 page 326. The Packaging and Distribution Expert Committee is proposing the following revisions which will update and expand the scope of the current chapter. Listed below are the key changes being proposed: 1. Change the title to “Elastomeric Components Used in Injectable Pharmaceutical Packaging/Delivery Systems”. 2. Emphasize the baseline requirements for the selection of thermoset and thermoplastic elastomeric components. 3. Expand the scope to include all elastomeric components used in an injection packaging system. Elastomeric components include, but are not limited to, those used for vials, bottles, prefilled syringes (plungers, needle shields, and tip caps), cartridges (plungers and seal liners), injection ports for flexible bags and infusion sets, and plungers for single-use syringes. 4. Delete the Heavy Metals ⟨231⟩ testing and add a modern method for extractable element determination. 5. Omit functionality tests and assessment from the chapter and move them to new chapters appearing in this issue of PF. a. Functionality tests appear in Elastomeric Closure Functionality in Injectable Pharmaceutical Packaging/Delivery Systems ⟨382⟩. b. Baseline information for the assessment is provided in Assessment of Elastomeric Closure Functionality in Injectable Pharmaceutical Packaging/Delivery Systems ⟨1382⟩. 6. Develop a new informational chapter, Elastomeric Evaluation of Elastomeric Components Used in Pharmaceutical Packaging/Delivery Systems ⟨1381⟩, that is meant to support the current chapter revision by: a. Describing elastomeric components and their materials of construction for use in pharmaceutical packaging systems b. Providing a high-level introduction to elastomer chemistry, manufacturing technology, and the post processing of components c. Explaining basic functional characteristics of components d. Discussing identification testing Tejie is a leading manufacturer of bromobutyl rubber stoppers for the pharmaceutical industry in China.  With a steadfast commitment to quality and innovation, we have perfected our manufacturing processes to deliver superior products that meet the stringent requirements of pharmaceutical packaging. Main types:- 1. 13mm 20mm for injectable powder  2. 13mm 20mm for lyophilization/Freeze-drying  3. 13mm,20mm,24mm,26mm,28mm,32mm,34mm for liquid dosage or infusion bottle 4. 20mm,25mm Polyisoprene gasket for Eurocap of infusion bags. We would welcome the chance to provide more information about our products and explore how we can work together to achieve mutual success. Best regards, Ada Song (Mrs.) Regional sales manager Jiangyin Tejie Rubber & Plastic Co.,Ltd M:+86-18210278669 E:hope@jytejie.com

We are delighted to introduce our comprehensive range of leading-edge pharmaceutical machines, specifically designed to increase productivity, improve accuracy, and streamline operations in the pharmaceutical industry. Capsule Filling Machine: Revolutionize your capsule production with this innovative machine designed for optimal performance, accuracy, and reliability. This machinery can seamlessly handle a vast variety of capsules, ensuring high-speed filling without compromising on quality. Automatic Capsule & Tablet Counting Machine: Say goodbye to manual counting errors with our automatic capsule and tablet counting machine. Filled with unparalleled technology, this machine provides precise, rapid counting that's essential for effective packaging and distribution. Blister Packing Machine: Enhance the safety and longevity of your products with our high-performance blister packing machine. Skilled at creating robust, airtight packaging, this machine ensures your products are protected while presenting them in a user-friendly manner. Mixer and Granulator: Achieve exceptional consistency and quality in your capsule and tablet formulations with our advanced mixer and granulator. This machine guarantees uniform mixing and granulation for optimal product quality. Powder Filling Machine: Meet your powder packaging needs with efficiency and precision using our powder filling machine. Regardless of the powder's texture or flowability, this machine offers speedy, error-free filling operations. Liquid Filling Machine: Cater to your liquid product demands with our state-of-art liquid filling machine. It provides accurate and speedy filling of various liquid products, reducing wastage and increasing operational efficiency. Our goal is to offer you reliable and efficient solutions for your pharmaceutical production needs. Together, these machines stand ready to elevate your production capabilities and set your business on a path towards greater profitability and success.

Serialization in the pharmaceutical industry involves assigning a unique serial number to each saleable unit, allowing for tracking throughout the supply chain from production to distribution. Check how RNJet H1+ TIJ can help to print batch number, LOT number or dynamic QR codes on pharmaceutical products. Learn more:- https://lnkd.in/e9hZazqY #Pharmaceutical #Serialization #BatchCoding #PharmaTech #TIJPrinter #TrackAndTrace #PharmaCompliance #PharmaPackaging #PatientSafety #PharmaManufacturing

We are delighted to introduce our comprehensive range of leading-edge pharmaceutical machines, specifically designed to increase productivity, improve accuracy, and streamline operations in the pharmaceutical industry. Capsule Filling Machine: Revolutionize your capsule production with this innovative machine designed for optimal performance, accuracy, and reliability. This machinery can seamlessly handle a vast variety of capsules, ensuring high-speed filling without compromising on quality. Automatic Capsule & Tablet Counting Machine: Say goodbye to manual counting errors with our automatic capsule and tablet counting machine. Filled with unparalleled technology, this machine provides precise, rapid counting that's essential for effective packaging and distribution. Blister Packing Machine: Enhance the safety and longevity of your products with our high-performance blister packing machine. Skilled at creating robust, airtight packaging, this machine ensures your products are protected while presenting them in a user-friendly manner. Mixer and Granulator: Achieve exceptional consistency and quality in your capsule and tablet formulations with our advanced mixer and granulator. This machine guarantees uniform mixing and granulation for optimal product quality. Powder Filling Machine: Meet your powder packaging needs with efficiency and precision using our powder filling machine. Regardless of the powder's texture or flowability, this machine offers speedy, error-free filling operations. Liquid Filling Machine: Cater to your liquid product demands with our state-of-art liquid filling machine. It provides accurate and speedy filling of various liquid products, reducing wastage and increasing operational efficiency. Our goal is to offer you reliable and efficient solutions for your pharmaceutical production needs. Together, these machines stand ready to elevate your production capabilities and set your business on a path towards greater profitability and success.

Pharmaceutical bottle-filling machinery all type of bottle filling machine, Blog, bottle filling machine, cane filling machine, glass jar filling machine, Manufacturing of pharmaceutical machinery, pharma machine, pharma machine, pharmaceutical companies, pharmaceutical industry / By deepenggworks Bottle-filling machines are required for pieces of equipment in various industries. Automating the process of filling bottles with liquids or powders well and exactly Manufacturing of pharmaceutical machinery: It is necessary to know how these devices work and the items they provide to choose the ideal one for your production needs. 1. Types of Bottle Filling Machines: Gravity Filling Machines: These machines pour liquids into bottles using gravity, and they work best for thin liquids. Pressure Filling Machines: These machines push liquids into bottles using pressure. They’re great for fizzy drinks and liquids that need exact fil-precisef Piston Filling Machines: These machines use pistons to carefully fill bottles with liquids or thick products. Overflow Filling Machines: These machines fill bottles to the same level by letting extra liquid spill over. Auger Filling Machines: These machines fill bottles with powders or small grains using an aspin screw. They’re excellent for precise filling. 2. Key Specifications to Consider: Filling Speed: Choose a machine with a filling speed works well with with the production rate required for your operation Fill Volume Range: Ensure the machine can hold the range of fill volumes required for your products, from small bottles to large bottle. Product Compatibility: Manufacturing of pharmaceutical machinery Verify that the machine is proper Accuracy: It’s important to understand how these gadgets work and what they can do so you can pick the right one for what you need to make. Adjustability: Look for machines with settings you can change to fit what you need to contain different bottle sizes, fill volumes, and product types. Cleaning and Sanitization: Consider ease of cleaning and sanitization features to maintain hygiene standards and prevent cross-contamination. Integration with the Production Line: pharmaceutical machinery Compatibility with conveyor systems and other production equipment ensure seamless integration into the production line. Footprint and Space Requirements: Consider the available space in your facility and choose a machine that fits within your layout. For more information read my blog on my website : https://lnkd.in/efugw9qF

The Tablet Manufacturing Process. The tablet manufacturing process is a critical step in the pharmaceutical industry. Tablets are a popular form of medication because they are easy to take and easy to store. However, making tablets is not as simple as just putting powder into a mold and pressing it into shape. There are several steps involved in the tablet manufacturing process, and each step must be carefully controlled to ensure that the final product meets all safety and quality standards. manufacturing process The first step in the tablet manufacturing process is pre-formulation. During this phase, the active ingredients and excipients (inactive ingredients) that will be used in the tablet are mixed together in the correct proportions. The mixture is then tested to ensure that it has the proper physical and chemical properties. The next step is the formulation, which is when the actual tablet is created. The mixture from pre-formulation is placed into a tablet press, which forms it into the desired shape and size. Once the tablets are formed, they are usually coated with a film to make them easier to swallow or to prevent them from disintegrating too quickly in the body. After coating, the tablets undergo final testing to ensure that they meet all quality standards. Once they have passed all quality testing, the tablets are packaged and shipped to pharmacies and other customers.

#PharmaceuticalRollerCompactor the CP 200 is a fully PLC and sensor controlled lab compactor, which is ideally suited for the development of pharmaceutical products and small production. https://bit.ly/30q6aTj #pharmaceuticals #pharma #pharmacist #pharmacy #medicine #health #medical #pharmacystudent #pharmacyschool #niper #pharmd #biotech #doctor #pharmaceutical #pharmacists #pharmacytechnician #pharmacylife #farmacia #biotechnology #pharmacognosy #research

Granulation is a critical process in the pharmaceutical industry, primarily used to improve the properties of powders in the production of tablets and capsules. There are several granulation techniques, each with its advantages and specific applications. The main granulation methods include: 1. **Wet Granulation**: - **High Shear Granulation**: Uses high-shear mixers to blend powders with a granulating fluid, forming dense granules. It's fast and effective for producing uniform granules. - **Fluid Bed Granulation**: Involves suspending the powder in a fluidized bed and spraying it with a granulating solution. It ensures good mixing and uniform granule formation. - **Spray Drying**: Converts a liquid feed into dry granules by spraying it into a hot drying chamber. It’s suitable for heat-sensitive materials. 2. **Dry Granulation**: - **Slugging**: Involves compressing the powder into large tablets (slugs), which are then broken down into granules. It's suitable for moisture-sensitive materials. - **Roller Compaction**: Compacts powder between two rollers to form sheets, which are then milled into granules. It's efficient and used for materials that cannot be processed with wet granulation. 3. **Melt Granulation**: - Uses a meltable binder to agglomerate the powder. The binder is melted, mixed with the powder, and then cooled to form granules. It’s beneficial for improving the dissolution rate of poorly soluble drugs. 4. **Spray Congealing**: - Involves spraying a molten mixture of drug and excipients into a cooling chamber, where it solidifies into granules. This method is suitable for creating sustained-release formulations. 5. **Hot Melt Extrusion**: - Combines powder with a polymer and passes it through an extruder, where heat and pressure create a homogeneous mixture that solidifies into granules. It’s used for modifying drug release profiles. Each of these granulation techniques has specific advantages and is chosen based on the properties of the active pharmaceutical ingredients (APIs) and the desired characteristics of the final product.