Gaia Science (M) Sdn Bhd’s Post

I am pleased to share our latest publication on the mechanochemical synthesis of pharmaceutical co-crystals at a kilogram scale. Unlike traditional solution-based methods that typically require large amounts of solvents and energy, our approach uses a drum mill from RETSCH. This demonstrates the potential of repurposing common industrial milling equipment for sustainable large-scale chemical transformations, which aligns with the industry's shift toward greener processes. Key highlights from our findings: -The reaction was completed within 90 min, yielding 99% of pure Ibuprofen:nicotinamide co-crystals without the need for additional purification. -Minimal metal contamination from abrasion was observed, well within acceptable regulatory standards for daily intake. I invite you to read our open access paper for a deeper dive into the methodology and results: https://lnkd.in/eZJJfqPb

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Precise and accurate pumping

𝐔𝐧𝐥𝐨𝐜𝐤 𝐭𝐡𝐞 𝐒𝐞𝐜𝐫𝐞𝐭𝐬 𝐨𝐟 𝐏𝐨𝐰𝐝𝐞𝐫 𝐁𝐞𝐡𝐚𝐯𝐢𝐨𝐫 𝐰𝐢𝐭𝐡 𝐅𝐓𝟒 𝐏𝐨𝐰𝐝𝐞𝐫 𝐑𝐡𝐞𝐨𝐦𝐞𝐭𝐫𝐲 Powder behavior is critical in product development and manufacturing processes, especially in industries like pharmaceuticals, food, and chemicals. At Seven Star Pharmaceutical Services, we offer 𝐅𝐓𝟒 𝐏𝐨𝐰𝐝𝐞𝐫 𝐑𝐡𝐞𝐨𝐦𝐞𝐭𝐞𝐫 analyses to characterize and optimize powder performance effectively. Our services include: ✅ 𝐃𝐲𝐧𝐚𝐦𝐢𝐜 𝐅𝐥𝐨𝐰 𝐀𝐧𝐚𝐥𝐲𝐬𝐢𝐬 – Understanding flowability during processing. ✅ 𝐁𝐮𝐥𝐤 𝐏𝐫𝐨𝐩𝐞𝐫𝐭𝐲 𝐓𝐞𝐬𝐭𝐢𝐧𝐠 – Measuring parameters like bulk density, compressibility, and permeability. ✅ 𝐒𝐡𝐞𝐚𝐫 𝐂𝐞𝐥𝐥 𝐓𝐞𝐬𝐭𝐢𝐧𝐠 – Evaluating powder behavior under compaction. ✅ 𝐄𝐧𝐯𝐢𝐫𝐨𝐧𝐦𝐞𝐧𝐭𝐚𝐥 𝐈𝐦𝐩𝐚𝐜𝐭 𝐒𝐭𝐮𝐝𝐢𝐞𝐬 – Assessing how humidity and consolidation influence powder properties. With precise data from FT4 Powder Rheometry, we help you optimize formulations, refine manufacturing processes, and improve overall product quality. Discover how our capabilities can elevate your projects. Learn more: https://lnkd.in/eQujwezZ #PowderCharacterization #FT4PowderRheometer #MaterialCharacterization #SevenStarPharma #CrystalStructure #PharmaceuticalResearch #SolidStateChemistry #AnalyticalTesting #Chemistry #PharmaceuticalScience #Research #CMC #CRO #Biotech #DrugDevelopment #API #CDMO #SCXRD #SmallMoleculeStructure #Innovation

Treating pharmaceutical contaminants in wastewater. To see how catalysts are synthesized for the tailored degradation of pharmaceutical contaminations in wastewater, check out this publication: https://lnkd.in/dEGECmGJ The authors Soudabeh Saeid, Ph.D., Six Sigma Green belt certified, Matilda Kråkström, Pasi Tolvanen Narendra Kumar, Kari Eränen, Markus Peurla, Jyri-Pekka Mikkola, Laurent Maël, Leif Kronberg, Patrik Eklund, and Tapio Salmi even go beyond catalyst characterization and also provide insights into oxidative degradation products of ibuprofene and implemented the process in a 1000 mL vessel using the SpinChem rotating bed reactor. This valuable contribution highlights the importance of proper sewage treatment for a common good! #AdvancedOxidationProcess #zeolites #catalyst #preparation #characterization #wastewater #treatment

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Sterilization is crucial in scientific research, healthcare, and pharmaceutical manufacturing, ensuring safety and quality by eliminating all life forms, including bacteria and spores. Effective sterilization requires a robust monitoring system, primarily using chemical and biological indicators. Chemical indicators, or process indicators, confirm that sterilization parameters like temperature and time have been met, providing a quick visual confirmation. Biological indicators, containing resistant spores, directly measure sterilization effectiveness, confirming microbial elimination. While chemical indicators are ideal for routine checks, biological indicators offer a more definitive assessment, essential for high-risk items such as surgical tools and pharmaceutical products. 🌱 IT Tech 👉 Click the link to view: https://lnkd.in/g4Cg3Npk #sterilization #chemical #Biological #indicator #scientific #lab #consumable #monitoring #ITTech #ITtechnologies #singapore #malaysia

Structurally complex fine chemicals are crucial in the pharmaceutical and agrochemical industries. However, synthesizing them, especially those with chiral centers, poses enormous challenges due to the need for catalyst-supported steps and high product purity.   Controlling stereoselectivity during synthesis is vital to avoid costly stereoisomer separation. Current batch processes have long changeover times and complex controls.   As a consequence, Fraunhofer IMM and its partner institutes develop a new modular technology platform to address these challenges, focusing on continuous flow synthesis under mild and selective conditions. Initial targets include chiral alcohols with functional groups impacting active pharmaceutical ingredients (API) bioavailability or allowing further selective functionalization.   Would you like to find out more? Then visit us at ACHEMA 2024 in hall 9.0 booth E64.   More information concerning our participation at the #ACHEMA24 can be found here 👉 https://lnkd.in/e5-priF5   Make a note of the lecture at the #ACHEMA on this topic in your calendar 👉 https://lnkd.in/enbbtux9   More about cascade reactions in flow can be found here👉 https://lnkd.in/esV3aiia   #cascadereactions | #finechemistry | #Fraunhofer | #WeKnowHow | Fraunhofer-Allianz Chemie

Table top vacuum freeze dryer operating video showing. Suitable for freeze drying of conventional materials in bulk (liquid, paste, solid). Widely used in medicine, pharmaceutical, biological research, chemical and food. #lyophilizer #Freezedryers #freezedrying