Georgia Hughes’ Post

Check out our white paper that highlights the challenges of obtaining needed long-term safety data after CAR T-cell therapy and potential ways to address them from patients' perspectives.

🗣️ New White Paper: Long-Term Follow-Up Studies from the Patient Lens Patient perspectives are crucial for sponsors and regulators to consider when designing each aspect of a clinical trial, including long-term follow-up (LTFU) requirements. In a recent survey conducted in collaboration with #EmilyWhiteheadFoundation, we gathered feedback from nearly 100 CAR T therapy recipients and caregivers. Findings revealed that participation in LTFU declines over time, with respondents highlighting challenges like travel barriers and insufficient understanding of certain LTFU processes and purposes. These challenges may prevent participation in LTFU studies for the required 15 years and warrant the need for more patient-friendly expectations, collaborative conversations, and creative modifications to the existing LTFU framework for CAR-T therapies. #CART #CellTherapy #PatientFirst #PatientVoice #ClinicalTrials Read the full report on our website: https://lnkd.in/ecmPmBTE

Clinical trials can be pivotal in a patient's care. When patients know they can receive free treatments, they're more willing to participate in important clinical trials. Hear more from Johnson & Johnson Innovative Medicine's Matthew L. Boyd, at the #BlackHealthMatters Summit as he shares why diversity in clinical trials is vital to healthcare and patients. Watch the full session now: https://bit.ly/3KaQOpb Session sponsored by Research Includes Me | Johnson & Johnson Innovative Medicine #ClinicalTrialDiversity #ClinicalTrials #BHMSpringSummitRewind24

If clinical trial procedures are not clear and confidently presented, patient trust can be undermined and lead to participant drop-outs. According to Director of Strategic Partnerships Will Ewart, training clinical research staff in how to interact with patients is key to participant retention. Read how simulation can support those efforts. More: https://lnkd.in/gpkkdDbZ

Building patient trust is crucial for clinical trial enrollment and retention. At Pro-ficiency, a Simulations Plus, Inc. company, our simulation-based training enables clinical researchers to hone their skills in realistic, risk-free environments, leading to smoother trial procedures and increased patient confidence. Traditional training methods fall short, while our simulation training provides continuous feedback and practice, reducing errors and enhancing performance. Real-time performance analytics ensure that research teams are well-prepared, fostering a transparent and trustworthy trial process that boosts patient comfort and participation.

Patient need is a compass, and it is incumbent upon us to follow where it leads. For Johnson & Johnson Innovative Medicine, it led us to develop a first-of-its-kind Guide to Expanded Access back in 2021. Now, three years later, and after positive feedback from patients and advocates alike, I’m proud to announce the release of a new 2024 edition, available here: http://bit.ly/3zBVnXs A resource requested by and co-created with patients, this guide provides patients, their caregivers, and their physicians much-needed clarity around expanded access – a potential pathway to investigational treatment outside of clinical trials for patients who are ineligible to participate in a trial, and whose disease has exhausted all available treatment options. With program requirements and details that vary country by country, expanded access can be challenging to understand and navigate. Now including 32 countries, the 2024 edition builds upon the original Guide and features updates directed by patient feedback and input. From the easy-to-navigate table of contents at the beginning to the glossary of key terms at the end, the patient voice is reflected across each page of the guide. It’s only by listening to patients and working with them that we can deliver the resources and information they need – something I learned firsthand as a nurse and continue to believe to this day. Being at the bedside of patients and working with families early in my career, I saw the sheer power of information. Illness is never easy to cope with but having access to the right resources can make all the difference. I may have retired my scrubs, but these experiences stick with me to this day and inspire me to deliver resources that are not only created for patients but with them. Guided by our bioethical principles, the Guide to Expanded Access brings to life J&J’s commitment to patient health and safety while enhancing transparency and clarity. A huge thank you to everyone who contributed to this effort – my Patient Strategies & Solutions team, our colleagues at Bionical Emas, and, of course, the patients we are privileged to serve. #MyCompany#ExpandedAccess#EAEducation

Just published 📖 𝗖𝗮𝗻𝗮𝗱𝗶𝗮𝗻 𝗖𝗼𝗻𝘀𝗲𝗻𝘀𝘂𝘀 𝗦𝘁𝗮𝘁𝗲𝗺𝗲𝗻𝘁 𝗼𝗻 𝘁𝗵𝗲 𝗠𝗮𝗻𝗮𝗴𝗲𝗺𝗲𝗻𝘁 𝗼𝗳 𝗩𝗲𝗻𝗼𝘂𝘀 𝗟𝗲𝗴 𝗨𝗹𝗰𝗲𝗿𝘀 (𝗩𝗟𝗨𝘀) Recently published in Wound Care Canada and developed by a diverse panel of experts, the Consensus Statement is an up-to-date practical guide for health-care providers managing patients with VLUs. The guide incorporates the latest clinical research, including the use of muscle pump activators (MPAs,) such as The geko® device, which significantly improve healing rates and patient outcomes. Key highlights include diagnosis and assessment of VLU’s, VLU treatment strategies, effective wound care recommendations and emphasis on patient education and prevention of recurrence. Click here for the Consensus Statement: https://lnkd.in/eG5hducz And here to learn more about the geko device: https://lnkd.in/e-6tnSp2

Say hello to Marylou, a 4-time clinical trial participant👋 When Marylou's cardiologist suggested she get involved with clinical trials she didn't know how wonderful the experience would be, and the impact it would have❣️ The Mended Hearts, Inc. and WomenHeart understand the barriers to participating in clinical trials. That's why we're talking with participants like Marylou to design resources to help individuals get enrolled📑 To learn more about if the clinical trial process is right for you and to access our Clinical Trial Discussion Guide visit the link below⬇️ https://bit.ly/4hQcWVx

Have you ever wondered what happens when you take part in a clinical trial? From signing up to follow up, our dedicated researchers and clinicians from Mater Clinical Trials partner with you through your healthcare journey, providing you with information, opportunity and choices. Watch to learn more about what happens if you choose to participate in a clinical trial, or click the link to search our current clinical trials: https://lnkd.in/gmHHCdJX

From HIT Consultant Media: "While cost savings are significant, the study emphasizes the profound impact VSOs can have on patient well-being. Frank McGillin, CEO of The Clinic by Cleveland Clinic, underscores this point: 'Imagine discovering an alternative treatment that is less invasive and has better outcomes… The difference The Clinic can make in the cost of care matters, but the impact of getting care right is even more powerful.'" Read the article: https://lnkd.in/eFu_HGVy